Magnumum

Magnumum is a complex of vitamins and microelements (magnesium lactate dihydrate and pyridoxine hydrochloride) in one preparation.

Indications of the magnumum

Indications for the use of Magnum are the following conditions that appear in connection with the deficiency of the necessary magnesium body:

• Atherosclerosis, ischemic heart disease;
• stones in the kidneys;
• high blood pressure;
• chronic fatigue;
• depressive conditions;
• stress;
• psycho-physical overstrain;
• tearfulness;
• muscle pain;
• high loads;
• children in the period of increased growth.
• Magnumum is recommended for use in combination therapy in persons with the following diseases:
• hypertension;
• pathology of the heart (arrhythmia, myocardial infarction)
• diabetes;
• osteoporosis.

[1], [2], [3]

Release form

The form of the release of the magnetum is a tablet of ellipsoidal shape, convex on both sides, white in protective, dissolving intestinal film.

The tablets protected by a cover, in blister packing. Quantity - ten pieces in a blister. Packed in a cardboard box of five blisters.

[4]

Pharmacodynamics

Magnesium is a powerful catalyst for enzymes involved in the reduction of cardiac muscle and neuromuscular stimulation. Stabilizes platelets and fibrinogen. Magnum helps to increase the amount of this element and stabilize the exchange reactions.

Vitamin B6 (pyridoxine hydrochloride) - is one of the regulators of amino acid metabolism. Vitamin B6 corrects metabolic processes in the myocardium, being a cardioprotector, hepatoprotector, neuroprotective agent.

[5], [6], [7], [8], [9]

Pharmacokinetics

Two components - pyridoxine hydrochloride and magnesium combine well and mutually complement each other's properties. Vitamin B6 improves absorption of magnesium, and also accelerates its absorption by cells, increases its content in the blood and red blood cells, reducing its excretion in the urine.

[10], [11], [12]

Dosing and administration

Magnumum is taken orally (orally). Tablets should be swallowed whole, so as not to damage the tooth enamel components of the medicine. Active ingredients Magnumum is absorbed quickly enough in the digestive tract. When you accumulate the right amount of magnesium, you must stop using the medication. It should be taken with a sufficient amount of drinking water (1 glass). Duration of therapy and dose Magnikum appoints a doctor.

The usual reception scheme is as follows:

• adults - 1-2 tablets three times a day.
• children, whose age is more than 6 years - 1 tablet 3 times a day.

If the patient has calcium deficiency in addition to lack of magnesium, then therapy should begin with magnesium compensation, and then prescribe medication to normalize calcium.

[19], [20], [21], [22]

Use of the magnumum during pregnancy

It is not advisable to use Magnum during pregnancy. There is insufficient research showing the effect of the drug on fetal development. The question of the therapy for this drug, future mothers, decides the treating specialist, weighing the possible benefits and harm for the woman and the child. During breastfeeding, if it is necessary to prescribe the medication, you must stop breastfeeding, since magnesium with mother's milk is passed on to the baby.

Contraindications

Magnumum is contraindicated for use in the following conditions: intolerance of any substance included in the drug, renal failure, hypermagneemia, phenolketonuria, myasthenia gravis, patients younger than 6 years.

[13], [14], [15],

Side effects of the magnumum

Side effects of Magnum are as follows:

• immune system-allergic reactions (with intolerance of any component);
• gastrointestinal tract - vomiting, diarrhea, epigastric pain;

If side effects occur, you should immediately contact a doctor who corrects the therapeutic regimen for taking the drug.

[16], [17], [18]

Overdose

Overdose Magnum occurs in the event of exceeding the dose prescribed by the doctor, which can cause the following phenomena: vomiting, a sharp drop in blood pressure, tremor, pain in the extremities, difficulty breathing and cardiac arrhythmia. There is no specific antidote. If there was an overdose of Magnum, it is necessary to perform lavage of the stomach to appoint enterosorbent drugs (not earlier than 1 hour after the last dose). In case of an overdose, symptomatic treatment is performed. It is necessary to replenish the water-electrolyte balance and the degree of hydration.

Patients with severe renal insufficiency to eliminate hypermagnesemia undergo hemodialysis.

[23], [24]

Interactions with other drugs

The absorption of magnesium in the intestine is reduced when using drugs containing calcium and phosphate; decreases absorption of tetracycline (recommended to observe a 3 hour interval between taking drugs); worse absorbed iron preparations; weaken the effectiveness of levodopa; with simultaneous admission with thrombolytic agents, the effectiveness of the latter decreases.

[25], [26], [27], [28], [29]

Storage conditions

Magnikum is stored as well as other medicines in the form of tablets. It is necessary to protect the drug from direct sunlight, temperature - 15-25 ° C, and protect from children.

Shelf life

Shelf life Magnumum is indicated on the package. Under favorable conditions, 2 years are stored (24 months). The drug is not recommended to use after the expiry date.