Pharmacodynamics Maaloksa determined by the action of substances that are part of its composition - aluminum hydroxide and magnesium hydroxide (in equal amounts). Upon ingestion into the stomach, these substances react chemically with free hydrochloric acid of gastric juice and neutralize it with the formation of salts - aluminum and magnesium chlorides - and water.
Thanks to Maalox, the content of hydroxide ions (pH) in gastric juice increases, and this effect is maintained for several hours, blocking the effect of acid on the gastric mucosa. But the natural process of digestion is not violated, and no additional production of hydrochloric acid occurs.
Aluminum and magnesium oxides also bind the bile acids that enter the stomach, preventing destruction of the mucous membrane. In addition, after a certain time, magnesium chloride, trapped in the intestine, begins to act as a laxative - by increasing the pressure in the lumen of the intestine and increasing its contractions. However, the laxative effect is insignificant, since aluminum weakens the activity of magnesium.