Low-pressure tablets: pharmacotherapy for arterial hypotension

Blood pressure values, which are lower by 20% or more than the standard accepted in clinical medicine (120/80 mm Hg), are considered a sign of low blood pressure or arterial hypotension. That is, hypotensive men can consider themselves men with blood pressure below 100/65 mm Hg. Art. And women with an index of 95/60 mm Hg. Art. They need low-pressure tablets.

This disease is acute and chronic, primary (physiological and pathological) and secondary (symptomatic, accompanying some kind of disease). To pathologically low blood pressure, hypotension is considered neurocirculatory and idiopathic. So it is unlikely that you will be able to determine the right medicine yourself, without the advice of a doctor ...

Moreover, when a doctor prescribes tablets from low blood pressure to a particular patient, first of all he takes into account the etiology of the disease. And among the causes of low blood pressure there may be general neurosis or depression, stress or anemia, cervical osteochondrosis or stomach ulcer, pancreatitis or heart failure, circulatory disorders, allergies or a lack of vitamins.

[1], [2], [3], [4], [5], [6], [7], [8], [9]

What are the tablets to drink at low blood pressure?

Given the individual condition of the patient who complains of low blood pressure, it is necessary to objectively evaluate a variety of factors, in particular, arterial tone and hemodynamic parameters (blood flow through the vessels), central and peripheral. Proceeding from the principle of adequate therapy adopted in medicine, it is recommended to use low-pressure tablets with reduced vascular tone, which will improve hemodynamics, especially blood supply to the brain (preparations of the alpha-adrenomimetic group).

In addition, with low pressure, doctors can prescribe medications to increase overall peripheral vascular resistance (OPSS), as well as tonic or neuro-metabolic stimulants.

Here are some names of low-pressure tablets that are used in the complex treatment of this pathology: Gutron, Ecstysten, Rantarin, Heptamyl.

Gutron

In the last decade in the complex therapy of hypertension, a drug from the group of alpha-adrenomimetics Gutron (a synonym - Midodrin) is used. The active substance of this medication is midodrine. In indications for the use of tablets from low pressure Gutron appear: primary neurogenic idiopathic hypotension; secondary orthostatic hypotension, including those with diabetes and Parkinson's disease; as well as the removal of symptoms such as dizziness, fainting, nausea, headache, blurred vision, numbness and tingling.

Pharmacodynamics of tablets from low pressure Gutron is based on the fact that, when ingested, the splitting of midodrin occurs with the release of a more active metabolite of desglymidodrine (desglymidodrine). Desglymidodrin has a vasoconstrictive effect by selective stimulation of postsynaptic alpha-adrenergic receptors in the autonomic nervous system. As a result, cardiac output, vascular tone and pressure increase, which significantly reduces the symptoms of hypertension caused by a decrease in blood flow to the brain.

Pharmacokinetics of tablets from low pressure Gutron is well researched, and the manufacturer of this drug claims that it is well absorbed after ingestion and after 10 minutes is found in the plasma of the blood, partially binding to proteins. Absolute bioavailability is 93%, and its components do not penetrate the blood-brain barrier (GEB). The final stage of metabolism occurs in the liver, and within a day the metabolites are completely excreted by the kidneys.

Form of release Gutron - tablets containing 0.0025 g (2.5 mg) of midodrin, in a package of 20 or 50 pieces.

Dosage of the drug Gutron is set by the doctor individually - depending on the indications and severity of the disease. For long-term treatment, the usual dose is 0.5 tablets (1.25 mg) 2 times a day - before meals, with a glass of water.

Contraindications to the use of tablets from low pressure Gutron are arterial hypertension, pheochromocytoma (hormonal active tumor of chromaffin cells of the sympathetic adrenal system of the adrenal gland), arteriosclerosis and obliterating endarteritis, acute inflammation of the kidneys (nephritis) and expressed renal failure, angle-closure glaucoma, benign enlargement of the prostate (hyperplasia prostate gland), hyperthyroidism, increased sensitivity to midodrin. Use of these tablets from low pressure during pregnancy is not provided.

Possible side effects of tablets from low pressure Gutron are as follows: sweating, pilomotor reaction (goose-skin), paresthesia (tingling sensation, crawling crawling), itching, chills, face redness, decreased heart rate (bradycardia), headache , dizziness, sleep disturbances, heartburn, dry mouth, nausea, dyspepsia, violation of urination, flatulence.

Interaction of tablets from low pressure with other drugs: with simultaneous application of Gutron with cardiac glycosides, reflex bradycardia is possible. Simultaneous reception with atropine and cortisone leads to a significant increase in blood pressure, and reception with reserpine completely neutralizes the effect of midodrin.

Conditions for storing tablets from low pressure Gutron - in a dark place at a temperature of not more than + 25 ° C. The shelf life of the drug is indicated on the package.

Ecstenen

The main pharmacological substance of the drug Ecdisten are biologically active phytoecdysteroids obtained from a medicinal plant levzeya safflower, growing in the Altai and Siberia under the alternative name "maral root". In medicine, rhizomes and roots of this plant are widely used as a restorative and adaptogenic medicinal product. Indications for the use of low-pressure tablets Ekdisten - as part of the complex therapy of asthenia, hypotension, physical and mental fatigue, neurasthenia, neuroses, decreased potency, and also during recovery after illnesses.

Dosing and Administration Ecdysten: tablets are taken entirely before meals - 1-2 tablets three times a day. The maximum single dose for adults is 0.025 g (25 mg), the maximum daily dose should not exceed 0.1 g. The duration of the course of treatment is 15-20 days, if necessary, a second course is conducted after a two-week break.

Among the side effects of low-pressure tablets Ecdysten indicated insomnia. Among the contraindications - nervous excitement, insomnia, hypertension, epilepsy, hyperkinesia (involuntary contraction of muscles).

The form of this medication is tablets of 0.005 g (5 mg). Conditions for storing tablets from low pressure Ecdisten - in a dry dark place.

[10], [11], [12]

Rantarine

The drug Rantarinum (Rantarinum) is an extract of the non-rooted antlers (antlers) of reindeer males. Has a tonic effect on the human central nervous system.

Among the indications for the use of tablets from low pressure Rantarin indicated lower blood pressure (arterial hypotension), reduced efficiency, increased fatigue, weakness, as well as suffered severe diseases.

This drug should be taken one tablet 2-3 times a day - 30 minutes before meals. The duration of treatment is 20-30 days. The repeated course of Rantarin can be done in a week.

Possible side effect of the drug is nausea. A contraindication to the use of tablets from low-pressure Rantarin include arterial hypertension, angina pectoris, cardiac arrhythmia, cardiac aneurysm, atherosclerosis, thrombophlebitis, thromboendocarditis, atherosclerosis of the aorta, nephritis and other kidney pathologies, and an acute stage of any infectious diseases.

Form release - coated tablets of 0.25 g (in a package of 50 pieces).

Conditions for storing tablets from low pressure Rantarin - in a place protected from light. Shelf life - 2 years from the date of production.

Heptamyl

Drug Heptamil (Geptamil) refers to neuroprotective drugs that improve cellular metabolism.

Pharmacodynamics tablets from low pressure Heptamyl: active ingredient of the preparation hydrochloride 2-amine-6-methyl-6-heptanol (heptaminol hydrochloride) is a synthetic metabolite, close to the natural metabolites of nerve cells, myocardium cells and striated muscles. Getting into the body, heptaminol hydrochloride acts on the centers of the hypothalamus and stimulates the physiological functions of the cerebral cortex and hypothalamus. As a result of this stimulation, the heart rate increases and the cardiac output increases, which activate the peripheral circulatory system and promote the return of venous blood to the arterial system. Due to this, the state of the vegetative-vascular system is improving.

As a rule, this drug (in the form of an injection solution in ampoules) is used to arrest a sharp drop in blood pressure in shock and myocardial infarction.

Heptamyl in the form of tablets (50 mg each) and a drop is recommended for acute and prolonged asthenic conditions, low blood pressure, acute and chronic heart failure.

Heptamil with low blood pressure and asthenia in adults is recommended to take one tablet (0.15 g) or 30 drops three times a day (the dosage of the drug for children depends on the age of 10-40 drops per day).

The storage conditions of the preparation are in a dry place protected from light.

The use of citramone to increase blood pressure

This drug is in any medicine cabinet, because it is considered one of the best medicines that relieve headaches. But how does the effect on the human body of Citramon: reduces or increases the pressure? There is an opinion that the drug contributes to lowering blood pressure, but it is mistaken, since the drug consists of three main components:

• paracetamol, which has antipyretic properties and blocks pain symptoms;
• aspirin, inhibiting cyclooxygenase (inflammatory process);
• Caffeine, which in this combination enhances the pharmacological properties of the two previous drugs. From its pharmacodynamics it follows that citramone, on the contrary, contributes to an increase in blood pressure.

Symptol

The drug Symptol can not be attributed to tablets from low pressure, since its release forms are 10% solution in vials and ampoules. But you can not pass over this medicine with silence, especially since the way to use it: drop 20-30 drops of solution on a piece of sugar and take it three times a day before eating.

Symptol helps narrow the peripheral blood vessels, which leads to increased blood pressure, increased heart rate and volume of circulating blood. Thus, this drug normalizes low blood pressure and improves the supply of cardiac muscle with blood.

Indications for its use are constitutional asthenia and low blood pressure associated with a decrease in vascular tone, including in the elderly, during pregnancy and childbirth, during surgery and in infectious diseases.

Symptol has the following contraindications: hypertensive disease, atherosclerosis and propensity to vasospasms. The drug with caution is prescribed for pathologies of the heart muscle and problems with the thyroid gland.

Among low-pressure tablets, there are drugs that doctors prescribe to patients quite rarely - with severe asthenia, a significant decrease in efficiency, depressive state and other psycho-vegetative disorders. These drugs are psychotropic series (antidepressants and tranquilizers), as well as nootropic drugs (neurometabolic stimulants).

People with low blood pressure should systematically - three times during the year - take vitamin complexes containing vitamins C, E, B, B5, B6, as well as phosphorus and calcium. The duration of one course of vitamin therapy should be 30-40 days (preferably in the fall and early spring). Particular attention to the intake of vitamins should be given to future mothers, since doctors categorically do not recommend the use of low-pressure tablets during pregnancy.

It should be stressed once again that all these medications should be prescribed by a doctor, since self-medication seldom relieves a person from illness, but can lead to undesirable, and sometimes irreversible, consequences.

By the way, in order not to worry about which pills to drink at low pressure, try brewing strong tea or making a cup of good (natural) coffee. And you can get a salty cucumber from the can ... Cookery salt (NaCl), as is well known, is contraindicated in hypertensive patients, but under the reduced pressure the sodium contained in it helps a lot.