Instillagel

Instillagel demonstrates local anesthetic and disinfectant effects. The medication has a combined composition - its components are lidocaine and chlorhexidine.

Chlorhexidine has an effect on gram-negative and -positive microbes, yeast, treponemas with dermatophytes, ureaplasmas, chlamydia and trichomonads. It continues to act actively in the presence of secretions, pus and blood.

Lidocaine has a local anesthetic effect.

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Indications Instillagel

It is used for the following disorders and procedures:

• catheterization in the urethra;
• cystoscopy or urethroscopy;
• performing operations in the bladder and prostate area;
• therapy for cystalgia or urethritis;
• vaginal sanitation before childbirth;
• hysteroscopy;
• curettage procedure for diagnostic purposes;
• endometrial biopsy;
• polypectomy in the cervical area;
• therapy for colpitis with cervicitis or endometritis;
• performing proctological operations;
• performing endoscopic examinations in children.

Release form

The medicinal component is released in the form of a gel, inside single-use plastic syringes with a volume of 6 and 11 ml.

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Pharmacodynamics

The transparent gel allows for a high-quality optical view, which is why it is often used when performing endoscopy.

The antimicrobial effect and pain relief appear after 5-10 minutes from the moment of drug administration.

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Dosing and administration

Each syringe can only be used once.

In case of urological pathologies, it is necessary to apply a small amount of the substance in the urethra area, and then place the cannula inside its opening, after which 11 ml of the substance is introduced (in men). During cystoscopy, it is necessary to treat the entire urethra with the drug (11 ml of gel is applied, as well as another 6 ml, if necessary). Children and women are administered 6 ml syringes. During various endoscopic procedures, after applying the gel, it is necessary to wait about 10 minutes to get the anesthetic effect.

When performing gynecological procedures, it is necessary to use 6-11 ml of the drug. First, it is necessary to cover the area of the external os with the drug, and then advance the tip of the syringe into the area of the cervical canal and uterine cavity.

If it is necessary to use Instillagel during lactation, you must stop breastfeeding for 12 hours from the moment of administration of the drug.

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Use Instillagel during pregnancy

It should be prescribed with great caution in the 1st trimester.

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Contraindications

Main contraindications:

• severe intolerance to parabens;
• bradycardia, which is pronounced (because there is a possibility of suppression of the heart's work).

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Side effects Instillagel

Side effects include: rashes, dermatitis of an allergic nature, Quincke's edema and burning in the treatment area.

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Overdose

Overdose of the gel may occur in case of severe damage to the urethra - this leads to simplification of lidocaine absorption with its subsequent systemic effect, manifested in the form of convulsions, bradycardia and collapse. Incorrect use of the drug may provoke orthostatic collapse.

In case of bradycardia, it is necessary to use β-adrenergic stimulants, and during convulsions, muscle relaxants with a short-term type of effect or barbiturates; in case of collapse, dopamine is administered intravenously.

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Interactions with other drugs

It is prohibited to combine the medication with iodine-containing drugs.

Instillagel is not compatible with detergents containing sodium laurisulfate and saponins, as well as with soap.

MAOIs are capable of potentiating the medicinal activity of lidocaine.

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Storage conditions

Instillagel must be stored at a temperature not exceeding 25°C.

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Shelf life

Instillagel can be used within a 5-year period from the date of manufacture of the therapeutic substance.

Analogues

Analogues of the drug are the gels Lidochlor and Katejel (containing lidocaine), as well as the spray Lidocaine Asept.

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Reviews

Instillagel is often used for various diseases. Reviews note its high medicinal activity and good tolerability. In children, this medicine allows local anesthesia for any type of endoscopy (colonoscopy or esophagoduodenoscopy). The gel improves the sliding of the instrument used and quickly anesthetizes the treated areas.

Comments also report that the drug is also used in combination therapy for premature ejaculation.

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