Ibuprom sprint capsules

Ibuprom Sprint in capsules is a non-steroidal anti-inflammatory drug (NSAID) with elements of pain relief, which has the Latin name Ibuprom Sprint Caps, as well as the international name Ibuprofen. The main active ingredient of the drug is ibuprofen.

Indications Ibuprom sprint capsules

Possessing anti-inflammatory and analgesic properties, indications for use of Ibuprom Sprint in capsules have a fairly wide spectrum of action.

• Symptomatic relief of toothache and headache.
• Premenstrual and menstrual symptoms.
• Muscle pain caused by a cold.
• Fever associated with infectious and cold diseases.
• Pathology of the musculoskeletal system, the source of which is a focus of inflammation: neuralgia, arthritis, bursitis, tendovaginitis of various origins, and others.
• Osteochondrosis, radiculitis.
• Migraine.
• Myalgia is a muscle pain that develops due to hypertonicity of muscle cells, both at rest and under stress.
• Arthralgia is pain in the joints.
• Ossalgia – “bone pain”.
• Pain symptoms following injury or surgery, accompanied by inflammation.
• Algomenorrhea is an inflammatory process in the pelvic organs.
• Childbirth: Ibuprom Sprint capsules are used as a tocolytic and analgesic agent.

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Release form

The drug is available in oval capsules with a soft, transparent, blue shell. The "filling" is an oily, transparent or slightly bluish substance containing 0.2 g of the active ingredient ibuprofen. The drug has prolonged properties.

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Pharmacodynamics

The active component of the drug dictates the pharmacodynamics of Ibuprom Sprint in capsules. The analgesic effect of the non-steroidal anti-inflammatory drug (NSAID) is obtained by suppression, slowing down the formation of prostaglandins. Ibuprom dulls the intensity of pain, helps relieve swelling and reduce high body temperature of the patient. Due to its prolonged characteristics, there is a long-term effect of the drug. The active substance effectively inhibits platelet aggregation (the ability of platelets to connect - "stick together" blood platelets), caused by collagens and adenosine diphosphate (ADP). The antipyretic properties of Ibuprom Sprint in capsules (antipyretic characteristics) are manifested in the effect of the drug on the cells of the hypothalamus.

The analgesic property of the drug is due to the suppression of the inflammatory process, a decrease in the synthesis of bradykinin and a decrease in the algogenicity of this chemical compound.

The anti-inflammatory nature of the drug is achieved due to the reduction of vascular permeability, activation of blood microcirculation, and blocking of energy sources for ongoing inflammation.

When administered orally, Ibuprom Sprint in capsules penetrates the gastric mucosa in small amounts, while the main component of the drug is absorbed in the small intestine. In this case, the maximum concentration of the basic substance in the blood plasma is achieved after one to two hours. In the case of rheumatoid manifestations of the inflammatory process, ibuprofen reduces pain symptoms, stops swelling growth, and relieves joint stiffness.

By acting on the brain receptors responsible for thermal regulation of the body, the drug manages to cope with the high temperature of the patient's body, demonstrating antipyretic properties. The effectiveness of the drug and the duration of its action depend on the starting temperature and the administered dosage. If the drug is administered once, its effect can be observed for eight hours.

In case of menstrual pain in women caused by dysmenorrhea of non-organic origin (primary dysmenorrhea), Ibuprom Sprint in capsules reduces intrauterine pressure and the intensity of uterine muscle contractions, which helps relieve pain.

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Pharmacokinetics

Ibuprofen is metabolized almost entirely in the liver, with about 90% of the drug being utilized by the kidneys and excreted in the urine unchanged or in the form of metabolites, and partly excreted in the bile. In the case of oral administration of the drug, the maximum concentration of the active substance in the blood plasma (Cmax) is observed within one to two hours after administration.

The pharmacokinetics of Ibuprom Sprint in capsules, confirmed by test studies, showed that in healthy people the half-life of the drug (T½) is about one hour and forty minutes. In patients with a history of kidney and/or liver pathology, this indicator varies from 1.8 to 3.5 hours. High commutation of the active substance with blood plasma proteins is noted - this index approaches 100.

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Dosing and administration

The drug Ibuprom Sprint in capsules is prescribed to adult patients and children over 12 years old, as well as those weighing more than 40 kg. A single dose of the drug is one or two capsules, corresponding to 0.2 - 0.4 g of ibuprofen. The drug should be taken every four to six hours. During the day, do not exceed the total dose of the drug of 1.2 g, which is equal to six units. For patients of retirement age, dosage adjustment is not required, with the exception of cases when the patient has a history of renal or hepatic insufficiency. The capsule of the drug is swallowed whole: either with food (this is especially important for patients who have hypersensitivity of the stomach), or after a meal with a sufficient amount of water.

The method of administration and dosage of the drug for children whose weight is less than 40 kg is selected individually. The maximum daily amount of ibuprofen is calculated as 20-30 mg per kilogram of the body weight of a small patient. This figure is divided into three to four doses, the interval between them should be six to eight hours. It is not worth exceeding the permissible dose of the drug, as this is fraught with serious complications.

• For children whose body weight falls within the range of 30 to 39 kg, the recommended starting amount is 0.2 g (one capsule). The maximum dosage per day is 0.8 g of ibuprofen, which is equivalent to four capsules.
• For children whose body weight is between 20 and 29 kg, the recommended starting dosage is 0.2 g (one capsule). The maximum dosage per day is 0.6 g of ibuprofen, which is equivalent to three capsules.

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Use Ibuprom sprint capsules during pregnancy

Any medication should be used with special caution during the period when a woman is expecting the birth of her child. The use of Ibuprom Sprint capsules during pregnancy is permissible only in the last third trimester, when the fetus has already formed. During the first and second trimesters of pregnancy, the drug can be prescribed to a woman only if the real benefit that the mother's body will receive outweighs the probable negative consequences for the fetus.

The active substance of the drug gets into the mother's milk in small quantities, but it is still allowed to take it during lactation. But if there is a medical need for long-term treatment or administration of large doses of the drug, in this case it is worth raising the issue of stopping breastfeeding.

Contraindications

Even if the drug seems harmless enough at first glance, you should be very careful when taking it, and especially when taking dosages. Contraindications to the use of Ibuprom Sprint in capsules are also quite varied:

• Hypersensitivity to ibuprofen or other components of the drug.
• Bleeding occurring against the background of gastric ulcer, occurring directly at the time of the necessary therapy or which has occurred two or more times before. Period of exacerbation of the disease.
• Manifestations of symptoms of an allergic reaction to the drug:
  • Rhinitis.
  • Rashes.
  • Hemorrhagic diathesis.
  • Quincke's edema.
• Introduction of Ibuprom Sprint in capsules together with other NSAIDs. This also applies to specific COX-2 inhibitors.
• Perforation of the walls and mucous membranes of the upper gastrointestinal tract. Possibility of bleeding.
• Ischemic heart disease (IHD), as well as severe forms of liver, heart and/or kidney failure.
• Bleeding of a cerebrovascular nature, other active type, as well as of unknown etiology.
• Babies whose body weight has not reached twenty kilograms or whose age is under two years.
• In case of dehydration of the body, caused by vomiting, small volumes of fluid intake, as well as manifestations of diarrhea (watery diarrhea).
• Bronchial asthma.
• Pathological disorders of porphyrin metabolism, acquired genetically or in the womb (eg, severe intermittent porphyria).
• Recurrent polyposis of the paranasal sinuses and other nasal tissues.
• Pathological disturbances in the blood clotting process.
• The rehabilitation period after coronary artery bypass grafting.

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Side effects Ibuprom sprint capsules

It is also worth mentioning the side effects of Ibuprom Sprint in capsules that may occur while taking it:

• Confusion and hallucinations.
• Decreased appetite.
• Bronchospasms.
• Allergic reaction to a drug:
  • Hives.
  • Rhinitis.
  • Swelling of the tongue plate and larynx.
  • Rash on the skin.
  • Anaphylactoid manifestations: Quincke's edema, anaphylaxis, up to and including shock manifestations.
• Lowering blood pressure.
• Headaches.
• Increased activity of sweat glands.
• Increased heart rate.
• Disorders of vision and hearing.
• Pain in the epigastric region.
• Disruptions in the functioning of the hematopoietic system.
• Nausea, heartburn and vomiting.
• Stomatitis and dry mouth.
• Hepatitis.
• Exacerbation of diseases in the digestive tract.
• Internal bleeding, which can be fatal if immediate medical care is not provided. This is especially true for people of retirement age.
• Exacerbation of diseases of the genitourinary system.
• Dizziness.
• Flatulence and diarrhea.
• Bad dream.
• Increased irritability and depression.
• Myocardial infarction.
• Emotional instability.
• Cardiac insufficiency.
• Liver dysfunction, especially with long-term use of Ibuprom Sprint capsules.
• Increased levels of urea in plasma.
• Pancreatitis.
• Liver failure.
• Anemia of various etiologies.
• Dermatological lesions.
• Autoimmune disorders.
• May provoke an attack of bronchial asthma.

Overdose

If a situation arises and the patient takes an excessive amount of ibuprofen, his body may respond with a response symptomatology, which depends on the dose of the drug administered and the period of time that has passed since taking the excessive dosage. An overdose of Ibuprom Sprint in capsules may manifest itself with the following symptoms:

• Pain in the epigastrium.
• Nausea, the high intensity of which can provoke vomiting.
• Painful manifestations in the head.
• An unpleasant background noise begins to accompany.
• Sleep and appetite disturbances.
• Dizziness.
• Diarrhea.
• Internal bleeding.
• Mood change.
• Spatial disorientation.
• Arterial hypotension.
• Exacerbation of bronchial asthma.
• Elevated body temperature.
• Cramps.
• Arrhythmia.
• Disruptions in the functioning of the respiratory system and kidneys.
• Increased prothrombin index.
• Hemolytic anemia is noted.
• Thrombocytopenia, granulocytopenia.

To stop the pathological symptoms, it is necessary to call an ambulance. Before its arrival, if less than an hour has passed since the overdose, it is necessary to provide the patient with first aid:

• Induce vomiting. This will allow the stomach to at least partially clear of excess drug.
• Using an enema, flush out the stomach.
• Give activated charcoal or any other sorbent to drink.

There are currently no single antidotes for the treatment of ibuprofen overdose.

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Interactions with other drugs

Above, a warning was already given about careful use of the drug, a measured dosage in each specific case. It is necessary to be even more vigilant during complex therapy. The interactions of Ibuprom Sprint in capsules with other drugs are quite ambiguous. In some cases, two drugs can enhance each other's action, and in others they can become antagonists.

Ibuprom Sprint in capsules is contraindicated for combined use with other drugs related to non-steroidal anti-inflammatory drugs (NSAIDs), as well as with acetylsalicylic acid, preventing the occurrence of side symptoms. Combined use of ibuprofen with glucocorticoids or painkillers can provoke gastrointestinal bleeding, and also increases the risk of eczema and ulcers on the mucous membrane of the digestive organs.

Ibuprofen reduces the effectiveness of antihypertensive drugs and drugs with diuretic properties. When used together with drugs that slow down the blood clotting process, mandatory monitoring of this indicator is necessary.

Methotrexate and Ibuprom sprint in capsules can provoke pronounced side effects. In case of using ibuprofen together with zidovudine, the probability of hemarthrosis and hemorrhage (hematomas) increases, especially in patients who are HIV-infected. Tandem with digoxin allows to obtain an increase in quantitative indicators of active substances of medicinal preparations in blood plasma.

Ibuprom sprint capsules and antithrombotic drugs provoke the occurrence of gastrointestinal bleeding. Tandem with quinoline antibiotics can provoke convulsive syndrome. Therapeutic therapy with ibuprofen and sulfonylurea requires constant monitoring of the quantitative indicator of glucose in the blood plasma. Complex treatment with the involvement of anticoagulants enhances the effect of the latter.

After the introduction of mifepristone, it is necessary to wait 8-12 hours before using any NSAIDs, including Ibuprom Sprint in capsules, since the combined use stops the effect of the first drug. It is strictly forbidden to take ibuprofen with cardiac glycosides. Such a combination negatively affects the human body, causing heart failure, an increase in the number of glycosides in the serum, inhibiting the intensity of glomerular filtration. Such drugs as colestyramine or antacids reduce the ability of ibuprofen to be absorbed. The analgesic properties of the drug in question can be enhanced by caffeine.

Storage conditions for Ibuprom sprint in capsules A cool place with a temperature not exceeding 25 ° C, protected from direct sunlight - these are the main storage conditions for Ibuprom sprint in capsules. The drug should not be accessible to children.

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Shelf life

Two years (or 24 months) is the expiration date of the drug, indicated on its packaging. It is recommended to carefully monitor the expiration date and after this date, do not take the expired medicine.

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