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Ibuprex Soft
Ibuprex Soft refers to the non-steroidal anti-inflammatory and antirheumatic drugs of the propionic acid derivative group.
Indications Ibuprex Soft
Ibuprex Soft is used as an anti-inflammatory, analgesic and antipyretic for symptomatic therapy of headache, toothache, pain during menstruation, pain in joints and muscles, neuralgia, and also to remove signs of fever-fever and chills.
Pharmacodynamics
The active substance of the preparation Ibuprex Soft isobutylphenylpropionic acid blocks the enzyme cyclooxygenase, which reduces the intensity of lipid mediators production of prostaglandins, which are present in virtually all tissues and organs and are conductors of pain, inflammatory and temperature reaction of the body.
Pharmacokinetics
After ingestion Ibuprex Soft is absorbed from the digestive tract for a short period of time. After 1-2 hours after taking the drug, its maximum concentration in the blood plasma is reached, after 3 hours - in the synovial fluid. The drug is transformed in the liver, and metabolic products are evacuated from the body with urine.
Use Ibuprex Soft during pregnancy
The use of ibuprex soft during pregnancy - for up to six months - is contraindicated, since the use of inhibitors of prostaglandin synthesis may adversely affect pregnant women or embryo development: the risk of abortion and fetal heart disease increases.
In the third trimester of pregnancy, ibuprex Soft may lead to premature closure of the arterial duct in the fetus with a high likelihood of developing stable pulmonary hypertension; the onset of labor may be delayed, and the length of labor increases with the risk of bleeding.
Contraindications
Contraindications to the use of Ibuprex Soft are: hypersensitivity to the components of the drug; allergy to acetylsalicylic acid (aspirin); peptic ulcer of the stomach and duodenum in the stage of exacerbation; the presence in the anamnesis of bleeding from the upper sections of the gastrointestinal tract associated with the intake of NSAIDs; acute failure of the heart, kidneys or liver; children under 12 years old.
Side effects Ibuprex Soft
Among the side effects of Ibuprex Soft are: headache, nausea, abdominal pain, itchy skin rashes, palpitations, lowering of blood pressure.
In patients with allergies and bronchial asthma Ibuprex Soft can cause bronchospasm, and with increased blood pressure - puffiness of soft tissues. Long-term use of the drug, as well as the excess of a therapeutically justified dosage, increases the risk of arterial thrombosis in the form of myocardial infarction or stroke.
Overdose
An overdose of the drug is accompanied by nausea, vomiting, headache and abdominal pain, drowsiness, nystagmus, visual impairment, tinnitus, renal insufficiency, seizures, a sharp drop in blood pressure
To remove symptoms of an overdose, it is necessary to wash the stomach, taking activated charcoal. With frequent or prolonged convulsions, intravenous diazepam or lorazepam is indicated.
Interactions with other drugs
It is inadmissible simultaneous application of Ibuprex Soft with acetylsalicylic acid and preparations of the group of non-steroidal anti-inflammatory drugs (NSAIDs).
Ibuprex Soft reduces the therapeutic effect of diuretics and hypotensive drugs. In case of taking along with antiplatelet and selective inhibitors of serotonin, as well as with corticosteroids - the risk of gastrointestinal bleeding increases.
Interacting with cardiac glycosides, Ibuprex Soft neutralizes their therapeutic effect. In addition, Ibuprex Soft enhances the side effects of cyclosporine and certain antibiotics.
Medical expert editor
Portnov Alexey Alexandrovich
Education: Kiev National Medical University. A.A. Bogomolets, Specialty - "General Medicine"
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Attention!
To simplify the perception of information, this instruction for use of the drug "Ibuprex Soft" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.