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Ibunorm Baby

Ibunorm baby for its dosage form is an oral white suspension that has a specific odor.

Indications Ibunorm Baby

Indications for use Ibunorm bebi can be justified when there is a need for symptomatic treatment of fever and pain that occurs due to a variety of factors, including fever after immunization.

The next case, when the drug can be justified and expedient, is the presence of acute respiratory viral infections. The use of Ibunorm baby for medicinal purposes is justified also in cases of flu, and in addition, at a time when the child's teeth are pricked. The drug is a good tool to help reduce the intensity of pain after tooth extraction.

Due to the pronounced analgesic and anti-inflammatory properties of this remedy, it can be useful in the presence of pains of various origins, including also those that cause them, inflammatory processes occurring in the body.   

Obviously, indications for the use of Ibunorm bebi occur when it is required to reduce the child's high temperature, which appears due to catarrhal diseases, inflammations, etc., and in addition, to reduce the intensity of the pain symptoms that appear in connection with this.     

Release form

Form of release Ibunorm baby is a suspension intended for oral ingestion. The suspension is white, it has a specific medical smell, it tastes sweet and sour, without fruit or any kind of candy flavor. It is offered in a vial of plastic, the volume of which can be 50 or 100 ml. In the cardboard packaging box, along with the vial of the drug and instructions for use, there is a dispensing device. It has the form of a special syringe, on which the measuring scale is applied. Since the suspension has a sufficiently thick consistency, the use of such a syringe provides convenience in obtaining the required dose of the drug and achieving great accuracy in the required amount of the drug for a single admission by the child inside.    

Proceeding from the fact that this drug is intended for children, this form of release of the drug in the form of a suspension is optimal, since it makes its application very simple and accessible for everyone. And due to the fact that the taste of Ibunorm bebi can be attractive enough for children, this is a positive factor in terms of the fact that the child is unlikely to resist and persist in refusing to take such a medicine.   

Pharmacodynamics

Pharmacodynamics Ibunorm baby is manifested primarily in the fact that its main component ibuprofen, which is a preparation of a non-steroidal group of anti-inflammatory effects, produces an analgesic effect and contributes to the normalization of body temperature. This is achieved due to the fact that there is an indiscriminate blockade of the enzyme cyclooxygenase (COX-1 and COX-2) in both its forms.

The action of Ibunorm baby is also that it acts as an inhibitor for the processes in which Pg-prostaglandins are synthesized. As a result of the effect of the drug, the activity of the main metabolic enzyme arachidonic acid responsible for inflammatory and painful pathogenesis decreases, as well as for the appearance of fever.       

The analgesic properties of this drug are activated by suppressing the production of prostaglandins, both at the periphery and inhibition of their synthesis in the central and peripheral nervous system. The effect of anelgizing is most pronounced when inflammatory genital pain occurs.     

Thus, the pharmacodynamics of Ibunorm baby has its own complex effects on the body, consisting on the one hand in helping to minimize the activity of the mechanisms of inflammation, and on the other - in reducing the intensity of pain symptoms arising in this regard.     

Pharmacokinetics

What happens with the drug after its intake and entry into the body, and what is the pharmacokinetics Ibunorm baby, consider below.

This drug is characterized by the property of good absorption from the gastrointestinal tract, which is almost completely realized. If you take Ibunorm baby at the same time as eating, there is a tendency to a slight slowdown in the rate of absorption. When the medicine is taken on an empty stomach, this causes TCmax 45 minutes, taking it after meals increases this time to one and a half to two and a half hours. In the synovial fluid, where a greater concentration is formed than in the blood plasma - from 2 to 3 hours.      

The main component of the drug - ibuprofen - binds to plasma proteins 90%.

After the absorption, the R form of the pharmacologically inactive ibuprofen in about 60 percent is converted to the active S-form.  

In the liver, the systemic and post-systemic metabolism occurs with the participation of the CYP2C9 enzyme. Elimination is characterized by two-phase kinetics, T1 / 2 2-2.5 h, with some retard forms it takes up to 12 hours.   

After 90% metabolism in the liver (T 1/2  is equal to 2-3 hours), it is exposed in the urine. In it, 70% has the form of metabolites and 10% leaves the body in an unchanged state. A 20-percent quantity is excreted through the intestines as metabolites.   

Use Ibunorm Baby during pregnancy

The drug Ibunorm baby can be used during pregnancy.

Contraindications

With all the absolute advantages and advantages of this anti-inflammatory and analgesic for children, there are also certain contraindications to the use of Ibunorm baby.

The first of them should be noted the following. Since this drug is characterized by a lower safety profile than paracetamol, whose action is limited only to the central level, its use for children younger than three months of age is allowed exclusively for medical purposes.  

This medicine is inadmissible for use if the child has chronic diseases, there is asthma, gastrointestinal ulcer, gastritis.   

A prohibitive factor in the use of Ibunorm baby may be the presence of hypersensitivity to ibuprofen, or to any other component contained in the preparation, as well as poor tolerability of other non-steroidal anti-inflammatory drugs.

Postponed diseases of bronchial asthma, rhinitis, urticaria, as the cause of which were the consequences of treatment with acetylsalicylic acid or other anti-inflammatory drugs of the nonsteroid group.

Abstain from use for the treatment of a child Ibunorm baby should be in cases where he has bleeding and there are differences in the normal coagulability of blood.

This drug is contraindicated when a child due to hereditary factors is allergic to fructose.

On the basis of all of the above, when deciding to start treatment using this drug, all existing contraindications to the use of Ibunorm baby should be taken into account in order to achieve effective healing and not cause harm to children's health.  

Side effects Ibunorm Baby

Side effects Ibunorm baby are characterized by a number of their specific manifestations, including: anaphylaxis, allergic reactions of a nonspecific type, the transition of bronchial asthma to the acute stage, the appearance of bronchospasm, various skin rashes.      

The gastrointestinal tract can manifest a reaction to the use of the drug in the form of attacks of nausea and vomiting, a feeling of discomfort and pain in the epigastric region, and also in the appearance of a laxative effect. There is a possibility of exacerbation of the gastric ulcer, bleeding may occur.    

The central nervous system signals a malfunction of the body due to the use of the drug headaches and dizziness.

In the organs of the cardiovascular and hematopoietic system, the negative consequences from the Ibunorm baby can manifest themselves as the development of anemia, the occurrence of agranulocytosis, leukopenia and thrombocytopenia.

 The urinary system, being exposed to possible adverse effects of this remedy, responds to this by the appearance of renal dysfunction.  

In the event that any side effects of Ibunorm beebi are detected, it causes the need for immediate discontinuation of the drug and the necessary symptomatic treatment.    

Dosing and administration

Ibunorm baby assumes an exclusively oral method of administration and its dose is calculated based on the ratio of the child's age and body weight.    

For the main indicator in determining the single dose should be taken from 5 to 10 mg per 1 kg.

The maximum allowable daily dose is 30 mg per kilogram of the child's body weight.  

For children under the age of six months, the norm is to take a suspension of 2 and a half milligrams three times a day with an 8-hour break. The maximum possible daily dose should not exceed 7.5 ml, which corresponds to 150 mg.    

In the period from six months to 1 year, the child should take 50 mg or 2.5 ml of medication every 6 hours. Within the norm is a dose of not more than 200 mg or 10 ml per day.

 A child from one year to three is given 100 mg (5 ml) of suspension with time intervals between doses of 8 hours. Daily dosage should be within 15 ml or 300 mg.       

At the age of 4-6 years, the maximum amount of suspension per day increases to 450 mg. Take medication is necessary for 150 mg three times throughout the day.    

Children from 7 years to 9 years of age should drink 200 mg (10 ml) of medication three times a day. The maximum total dose, therefore, is 600 mg.  

From 10 years before the 12th anniversary, the daily dose of the suspension is 900 mg. This amount should be consumed in three 300 mg doses, respectively.    

The dose for postimmunizational fever is 2.5 ml at a time, and then, if necessary, another as much suspension after 6 hours. It should be remembered that the total amount of medication taken should be within 5 ml throughout the day.    

The way of administration and doses of Ibunorm baby are determined based on the individual characteristics of the child's body, in particular - the body weight, and in addition, its age, and the nature of the course of the disease should be taken into account. The course of treatment is usually equal to three days, but in some cases it may take longer to apply the drug. 

Overdose

Sometimes, due to an incorrect calculation of the dose of the child, which is optimal for a particular age, and also that which corresponds to the mass of his body, an overdose of Ibunorm baby may appear.

This unfavorable for children's health situation can occur when the amount of medication taken internally exceeds 400 mg per 1 kg of the child's body weight. Because of this, there is acute intoxication, which is accompanied by a number of the following negative phenomena.

There is nausea, vomiting, abdominal pain, headache and dizziness. The child falls into a drowsy state, he has a visual impairment, nystagmus arises. It can also begin ringing in the ears and a decrease in blood pressure. In certain circumstances, there are phenomena of acidosis, kidney failure develops, there is a loss of consciousness.             

When there is an overdose of this medication, a specific antidote in this case is not possible in the absence of such an antidote in principle. Therefore, the best way to resist this condition and prevent further development for its cause of all kinds of complications is the immediate cessation of the use of the drug and the appointment of therapy for symptomatic treatment.       

Interactions with other drugs

There are a number of fundamental principles that characterize the interaction of Ibunorm baby with other drugs.

So the expediency of combining within one treatment course and the effects produced by their interaction within the same treatment course, with respect to certain medicines, seems unjustified. First of all it concerns the joint use of Ibunorm baby and acetylsalicylic acid. In addition, recommendations often often do not combine the treatment with ibuprofen with other non-steroidal anti-inflammatory drugs and glucocorticosteroid-type drugs. The rationale for this statement may be the likelihood that this may be a risk factor for increasing the likelihood of side effects in the gastrointestinal tract.      

An adverse effect can also be caused by the use of anticoagulants, since this can provoke bleeding.  

It is necessary to show maximum caution and attention, using together with the drug diuretics - in order to avoid possible negative reactions affecting the kidneys.

It is necessary to weigh everything carefully before sharing with Ibunorm baby, both lithium preparations and methoxate, because there is evidence of an increase in their content in the blood.        

Increased nephrotoxicity in turn can provoke and cyclosporamine. 

Thus, the course of treatment should be designed taking into account the positive or undesirable consequences that may result from the interaction of Ibunorm baby with other drugs.

Storage conditions

Storage conditions Ibunorm baby requires that the product be packaged in its original packaging and kept out of reach of children at an ambient temperature not exceeding 25 degrees Celsius.

Special instructions

The drug belongs to the therapeutic means of the non-steroid group, antirheumatic and anti-inflammatory action.      

The effect produced by this suspension in the body is that it acts as an inhibitor for processes in which prostaglandins are produced that are mediators for inflammatory phenomena, fever and pain symptoms. 

The effect of the drug is the actualization of its analgesic, antipyretic and anti-inflammatory properties. In addition, ibuprofen, the main active ingredient that is part of this medication, leads to a decrease in platelet aggregation activity.

When taken orally, ibuprofen tends to be absorbed to the maximum extent for a short time. The greatest concentration in the blood is reached after a period of one to two hours. Ibuprofen is almost completely bound to the proteins contained in the blood plasma, and its presence appears in the synovial fluid. As a result of metabolization of ibuprofen, two inactive metabolites are formed in the liver. The kidneys take them out and in full for a short time. About one-tenth of the volume is exposed unscrewed.   

Shelf life

Shelf life of the drug is 3 years.

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Attention!

To simplify the perception of information, this instruction for use of the drug "Ibunorm Baby" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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