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Heparin ointment from edema
Last reviewed: 23.04.2024
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Heparin ointment belongs to the pharmacological group of direct acting anticoagulants (ATX - C05BA53), that is, this drug prevents blood clotting. However, the active substance of this drug - heparin sodium - has an effect on a wide range of other conditions, and this explains why Heparin ointment is used for swelling.
According to the instructions, the main indications for the use of Heparin Ointment include superficial thrombophlebitis and phlebitis of the extremities, varicose veins, hemorrhoids of the external nodes with hemorrhoids, bruises, subcutaneous hematomas. In addition, Heparin ointment is applied from leg edema and various local infiltrates.
[Pharmacodynamics
Heparin is a polyanionic, that is, negatively charged, heteropolysaccharide (glycosaminoglycan) with a direct chain of covalently bound sulfate and carboxyl subunits. The anticoagulant effect of heparin is related to its ability to increase the activity of antithrombin III (a specific protein of the blood coagulation system), resulting in the inhibition of most of the coagulation factors. And due to a significant negative charge, heparin also interacts electrostatically with thrombin (clotting factor II), which leads to inactivation of thrombin.
Since heparin is negatively charged, its molecules can bind large amounts of interstitial fluid containing various cations. Therefore, Heparin ointment from edema has an antiexudative effect, including when fluid retention in the tissues.
Pharmacokinetics Heparin ointment manufacturers of the drug in the instructions are not provided.
Dosing and Administration
Heparin ointment from swelling on the feet is applied to the skin with a very thin layer, followed by a gentle rubbing, no more than twice a day. In a similar way, Heparin ointment is applied from eye swelling: the drug should be applied to edematous areas under the eye sockets, but not to the eyelids (ointment should not fall into the eyes).
With an external application, an overdose of the ointment is unlikely.
Contraindications for use
Heparin ointment from edema is not used for any damage to the skin (abrasions, wounds, ulceration), the presence of skin rashes, with violations of blood clotting with a low level of platelets in the blood. The use of Heparin ointment from swelling during pregnancy is allowed only according to the doctor's prescription, taking into account the results of the blood test for platelets.
Side effects of Heparin ointment from edema
The main side effects that Heparin ointment can give from swelling are manifested in the form of redness of the skin at the site of application, hives and itching.
Interactions with other drugs
Heparin ointment from edema should not be used when taking antibiotics of the tetracycline group, non-steroidal anti-inflammatory drugs and anti-allergic antihistamines.
Storage conditions: at a temperature of + 12-15 ° C.
The expiration date is indicated on the package of the preparation.
Attention!
To simplify the perception of information, this instruction for use of the drug "Heparin ointment from edema" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.