Hepacinar

Hepacinar demonstrates a choleretic effect. Its medicinal activity is due to the action of bioactive components that are contained in the composition of drugs.

The extract obtained from artichoke leaves helps the secretion and outflow of bile, and with this hepatic secretion of bile acids and excretion of fluid. [1]

The use of artichoke extract reduces serum values of cholesterol and triglycerides; at the same time, the most rapid development was the decrease in the indices of the LDL fraction.

Indications Hepacinar

It is used in case of dyspeptic disorders ( bloating, , belching , feeling of heaviness in the epigastric zone, as well as nausea) and having a hypotonic-hypokinetic form of  bile duct dyskinesia .

In addition, it is prescribed in the case of cholecystitis of a non-calculous variety (chronic stage) and hepatitis of a different nature (chronic).

Release form

The release of the medication is realized in capsules - 10 pieces inside the cell plate; the pack contains 2 such plates.

Pharmacodynamics

Choleretic effect.

By potentiating bile secretion, the severity of signs of digestive dysfunction is weakened, which helps to facilitate the process of fat digestion and protects the intestinal mucosa from the effects of acids. Bile acids entering the duodenum 12 stimulate intestinal peristalsis, helping to improve digestive activity.

It is believed that such effects are provided by cynarin with chlorogenic acid, caffeine and other acids, which stimulate the secreting activity of the liver, and in addition to bitterness with sesquiterpene lactones.

Impact on lipid metabolism.

Elements of artichoke extract are able to potentiate cholesterol elimination - by stimulating bile secretion, as well as inhibiting cholesterol binding.

Dosing and administration

The medicine is applied in 1 capsule 3 times a day. You need to consume the capsule 15-30 minutes before a meal.

The size of the portion and the duration of treatment are selected by the doctor personally - taking into account the intensity of the development of the pathology. Often this cycle lasts 14-21 days.

• Application for children

Hepacinar is not prescribed to persons under 12 years of age.

Use Hepacinar during pregnancy

The medication is not used in pregnant women and during breastfeeding.

Contraindications

The main contraindications:

• strong sensitivity associated with artichoke and other plants from the Asteraceae subspecies;
• blockage of the bile ducts;
• cholelithiasis;
• active phases of renal / hepatic disease;
• insufficiency of liver function.

Side effects Hepacinar

Prolonged use of large dosages of the medication can cause diarrhea, nausea, pain in the upper abdomen, heartburn, and signs of allergies.

Overdose

In case of poisoning, side effects can be potentiated.

In such cases, you need to discontinue the medication and perform a gastric lavage. Symptomatic actions are also carried out. Hepacinar has no antidote.

Interactions with other drugs

The drug is able to reduce the effect of coumarin anticoagulants (among them warfarin with phenprocoumon). Because of this, the dosage of the latter must be adjusted.

Combination with cholesterol-lowering and -azotemic substances can potentiate their therapeutic activity.

Storage conditions

The hepacinar must be kept in a place out of the reach of small children. Temperature indicators - no more than 25 ° С.

Shelf life

Hepacinar can be used for a 2.5-year term from the date of release of the pharmaceutical product.

Analogs

The analogs of the drug are the substances Allochol, Rafacholin, Tsinariks with Artichoke extract, Holyver and Gepar-pos with Tansy flowers. In addition, also Holagogum and Phytohepatol with Cholagogue collection.