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Hepacinar
Last reviewed: 04.07.2025
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Hepacinar demonstrates a choleretic effect. Its medicinal activity is due to the action of bioactive components contained in the composition of the drug.
An extract obtained from artichoke leaves helps the secretion and flow of bile, and with it the hepatic secretion of bile acids and the excretion of fluid. [ 1 ]
Artichoke extract consumption reduced serum cholesterol and triglyceride levels, with the most rapid reduction in LDL fraction.
Indications Hepacinar
It is used in cases of dyspeptic disorders ( bloating, belching, a feeling of heaviness in the epigastric region, as well as nausea) and dyskinesia of the bile ducts in a hypotonic-hypokinetic form.
In addition, it is prescribed in cases of non-calculous cholecystitis (chronic stage) and hepatitis of various origins (chronic).
Release form
The drug is released in capsules - 10 pieces inside a cell plate; the pack contains 2 such plates.
Pharmacodynamics
Choleretic effect.
By potentiating bile secretion, the severity of signs of digestive dysfunction is weakened, which helps to facilitate the process of fat digestion and protects the intestinal mucosa from the effects of acids. Bile acids entering the duodenum stimulate intestinal peristalsis, helping to improve digestive activity.
It is believed that such effects are provided by cynarin with chlorogenic acid, caffeoylquinic and other acids that stimulate the secretory activity of the liver, and in addition to this, bitters with sesquiterpene lactones.
Effects on lipid metabolism.
Elements of artichoke extract are able to potentiate cholesterol elimination – stimulating bile secretion and also inhibiting cholesterol binding.
Dosing and administration
The medicine is used 1 capsule 3 times a day. The capsule should be taken 15-30 minutes before meals.
The portion size and duration of treatment are selected by the doctor individually, taking into account the intensity of the pathology. Often, such a cycle lasts 14-21 days.
- Application for children
Hepacinar is not prescribed to persons under 12 years of age.
Use Hepacinar during pregnancy
The medication is not used in pregnant or breastfeeding women.
Contraindications
Main contraindications:
- severe sensitivity to artichoke and other plants of the Asteraceae subspecies;
- bile duct obstruction;
- cholelithiasis;
- active phases of kidney/liver diseases;
- liver failure.
Side effects Hepacinar
Long-term use of high doses of the drug can cause diarrhea, nausea, pain in the upper abdomen, heartburn, and signs of allergy.
Overdose
In case of poisoning, side effects may be potentiated.
In such cases, the drug should be discontinued and gastric lavage should be performed. Symptomatic actions are also carried out. Hepacinar has no antidote.
Interactions with other drugs
The drug can reduce the effect of coumarin anticoagulants (including warfarin with phenprocoumon). Because of this, the dosage of the latter must be adjusted.
Combination with hypocholesterolemic and -azotemic substances can potentiate their therapeutic activity.
Storage conditions
Hepacinar should be stored in a place out of reach of small children. Temperature indicators – no more than 25°C.
Shelf life
Hepacinar can be used for a period of 2.5 years from the date of release of the pharmaceutical product.
Analogues
The analogs of the drug are Allochol, Raphacholine, Cynarix with Artichoke extract, Holiver and Gepar-pos with Tansy flowers. In addition, there are also Cholagogum and Fitogepatol with Choleretic collection.
Attention!
To simplify the perception of information, this instruction for use of the drug "Hepacinar" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.