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Helpex Breeze
Last reviewed: 23.04.2024
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With colds, patients often complain about a strong cough that does not allow them to breathe normally and significantly worsen the overall condition. Of course, coughing is not an independent disease, but only a symptom that you can easily get rid of using Helpex Breeze.
This drug is a combined agent with mucolytic action, which is often used in the treatment of colds.
Indications of the helpex Breeze
"Helpex Breeze" tablets are prescribed during treatment of catarrhal cough (acute and chronic type), as well as in other similar diseases, when the amount of secretion in the bronchi is disturbed and the secret itself disappears. It is recommended to drink the remedy during the treatment of obstructive lung diseases (chronic type), bronchitis (chronic type), pneumonia, asthma (bronchial type), bronchoectatic disease, laryngitis, cystic fibrosis and tracheitis.
If the patients showed a syndrome of so-called "shock lungs", you can use this drug for therapy or prevention. It is also sometimes used after carrying out operations on the airways.
Release form
The drug is manufactured by the Indian company Sava Helskea Ltd in the form of tablets, which are covered on the outside with a special coating for better resorption in the body. It has the appearance of round, slightly orange-tinted tabs on both sides. They have a pleasant smell of vanilla.
Pharmacodynamics
The drug contains the following active components: ambroxol hydrochloride and acetylcysteine.
Ambroxol Hydrochloride is an effective expectorant and mucolytic substance. It also has an antioxidant, immunomodulatory, insignificant antitussive effect, reduces signs of inflammation. Thanks to the stimulation of serous cells in the glands of bronchial mucosa, the amount of secreted secretion increases. This breaks the ratio of mucous and serous components.
Due to the action of this component, sputum is normalized, its adhesiveness decreases, it becomes less viscous. Also, the activity of the ciliated epithelium in the bronchi is stimulated, which prevents the phlegm from sticking together and helps it to go out faster. It increases the number of surfactants in the lungs without causing bronchial obstruction. In patients with asthma, during therapy with this drug, hyperreactivity of bronchial muscles decreases. After using Helpex Breeze, the surfactant layer is resumed in the patient.
Acetylcysteine is a mucolytic agent with an expectorant effect. Upon ingestion, the patient breaks the bisulfide bonds of the mucopolysaccharide, which is in sputum. This allows you to make the secret less viscous. It binds free radicals.
Pharmacokinetics
The pharmacokinetic properties of the Helpex Breeze preparation were not investigated.
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Dosing and administration
The drug can be used from the age of twelve. The dosage is prescribed by the attending physician, but it is usually the following: one Helplex Breeze tablet three times in 24 hours. Do not exceed the prescribed dose, as this can lead to an overdose and the appearance of unpleasant symptoms.
If you take the drug without first consulting a doctor, therapy can not last longer than seven days.
Use of the helpex Breeze during pregnancy
It is not recommended to use "Helpex Breeze" for the treatment of pregnant women in the first trimester of pregnancy. To date, there is no evidence of exactly how acetylcysteine and ambroxol hydrochloride affects the fetus. Therefore, it should not be used by pregnant women. The attending physician may prescribe this medication only if there is a possibility of a lethal outcome for the mother.
Ambroxol hydrochloride and acetylcysteine easily penetrate into breast milk, so during lactation, the drug is also not recommended. If the remedy has been prescribed, stop feeding the baby for the period of therapy.
Contraindications
Mucolytic preparation "Helpex Breeze" is forbidden for patients with gastric ulcer, intolerance to acetylcysteine or ambroxol hydrochloride, duodenal ulcer (acute phase), pulmonary hemorrhage or hemoptysis.
Side effects of the helpex Breeze
- Anaphylactic shock and other reactions.
- Hives and skin rashes.
- Angioedema and edema.
- Dyspnea.
- Itching of the skin.
- Fever.
- Eczema or erythema.
- Lyell's syndrome.
- Stephen-Johnson Syndrome.
- Increased salivation.
- Nausea with vomiting.
- Heartburn.
- Pain in the abdomen.
- Dyspepsia.
- Rhinorrhea.
- Dysuria.
- Noise in ears.
- Headache.
- Tachycardia.
- Anemia.
Overdose
Cases of drug overdose, in the composition of which is acetylcysteine, was not recorded. Sometimes there is an overdose of ambroxol hydrochloride, but there are no signs of severe intoxication in the patient. Sometimes diarrhea or hypersalivation may occur.
For the treatment of overdosage, gastric lavage is used (if there is vomiting). Symptomatic therapy is indicated for milder symptoms.
Interactions with other drugs
In the interaction of acetylcysteine with other bronchodilators, synergy occurs. With simultaneous application of Helpex Breeze and drugs with paracetamol, acetylcysteine can reduce the hepatotoxic effect of the latter. Increases the amount of glutathione in the body, which is responsible for the binding of free radicals.
When using ambroxol hydrochloride with some antibiotics (cefuroxime, amoxicillin, doxycycline and erythromycin), the drug increases their concentration in secretion and sputum.
If you simultaneously use "Helpex Breeze" and other antitussive drugs, it can lead to the accumulation of mucus and worsen cough. This combination can be used only after the recommendation of the attending physician.
Simultaneous application of Helpex Breeze with certain antibiotics (tetracycline, amphotericin B, ampicillin, aminoglycoside, cephalosporin) may result in a decrease in the effect of both drugs. It is very important to take these funds with an interval of two hours.
When interacting with activated carbon, the effectiveness of acetylcysteine decreases.
If you use acetylcysteine along with nitroglycerin, this can cause an increase in the vasodilating effect of the latter.
Long-term therapy with histamine and acetylcysteine is unacceptable, as this can cause unpleasant symptoms (itching, vasomotor rhinitis, headaches).
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Storage conditions
It is very important to keep the Helpex Breeze in a place that is inaccessible to young children. The air temperature should not exceed +25 degrees.
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Shelf life
Shelf life - no more than four years.
Attention!
To simplify the perception of information, this instruction for use of the drug "Helpex Breeze" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.