Haloperidol forte

Haloperidol forte belongs to a group of drugs that are intended for the treatment of psychotic disorders. Today, people suffering from acute and chronic forms of this process are quite common. In the current situation, you can’t leave everything to chance; complex therapy and maintenance of the person’s condition are necessary.

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Indications Haloperidol forte

Indications for the use of Haloperidol forte are unambiguous, these are mental disorders. Moreover, they can take absolutely any form. These disorders include schizophrenia, epileptic, depressive and alcoholic psychosis.

The drug is taken in case of psychomotor agitation of various genesis. Hallucinations, depression and psychosomatic disorders are eliminated. Today, many people suffer from stuttering, this is caused by problems with the uneven system. It is necessary to take the drug in this case. It is possible to eliminate such consequences, in more complex situations the drug is used as a maintenance therapy.

Oligophrenia, disorders associated with childhood and old age are the main indications for use. Vomiting, hiccups, elimination of nausea and other unpleasant symptoms caused by chemotherapy. In all these cases, the drug is taken. Haloperidol forte is a universal remedy that can help solve many problems, but it is not recommended to take it on your own.

Release form

The drug is available in tablet form. It contains 5 mg of the active substance haloperidol. Additional components include silicon oxide, magnesium stearate, talc, starch and lactose.

The tablets are white, in some cases a similar shade. There is practically no smell, the medicine looks like a flat disk. This simplifies the process of swallowing.

There is no other form of release. Haloperidol forte is presented exclusively in tablets. This form allows you to take them with you and take them at any convenient time.

When purchasing a product at a pharmacy, pay attention to its appearance. The tablets should not have a shade other than white. The package comes with instructions. You should not take the product without them. The pharmacist should provide instructions if they are not available. You need to buy the product in a trusted place and in the amount you need. Haloperidol forte is a universal medicine that can alleviate a person's condition in a short time.

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Pharmacodynamics

Pharmacodynamics of the drug - an antipsychotic agent, which is a derivative of butyrophenone. The drug has a pronounced antipsychotic effect. This process is caused by the blockade of depolarization or a decrease in the degree of excitation of dopamine neurons.

The drug has a moderate sedative effect. This occurs due to the blockade of α-adrenoreceptors located in the brainstem. This allows the vomiting center to be properly affected and unpleasant symptoms to be relieved.

Long-term use of the drug may be accompanied by a change in endocrine status. This process occurs in the anterior pituitary gland. Here, prolactin production increases and gonadotropic hormone production decreases significantly.

The drug has virtually no anticholinergic effect. Haloperidol forte is able to eliminate persistent personality changes, mania, and increase a person's interest in the surrounding world. In addition, it has an activating effect. Children suffering from hyperactivity, after taking the drug become a little calmer, excessive motor activity is eliminated. Haloperidol has a prolonged effect.

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Pharmacokinetics

The pharmacokinetics of the drug is due to rapid absorption. Thus, the drug is absorbed from the gastrointestinal tract by almost 60%. The maximum concentration of active substances in the plasma is achieved 3-6 hours after a person has taken the drug. If it was an intramuscular injection, then after 10-20 minutes.

The "first pass" effect occurs in the liver. The product binds to proteins by 92%. With the participation of isoenzymes, the active substances are metabolized in the liver quite actively. There are no active metabolites.

When taken orally, the drug is absorbed by 60% from the gastrointestinal tract. It can easily penetrate histohematic barriers, including the BBB. The drug is excreted with breast milk after 24 hours when taken orally. If the drug entered the body intramuscularly, then after 21 hours. The drug is completely eliminated from the body after 3 weeks. 40% comes out through the kidneys, and 15% through the intestines with the help of bile. Haloperidol forte does not pose a high risk to the body.

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Dosing and administration

The method of administration and dosage of Haloperidol forte is determined by the attending physician. When taken orally, the initial dose is 0.5-5 mg of the drug up to 3 times a day. If we are talking about elderly patients, the dosage does not exceed 0.5-2 mg. In the future, everything depends on the treatment itself. In most cases, the dose is increased to 5-10 mg.

Increased doses in the form of 40 mg are taken extremely rarely. In periods of absence of concomitant diseases. For children, the dose should not exceed 25-75 mcg in 2-3 doses. If intramuscular administration is necessary, the initial dosage is 1-10 mg. The interval between such administrations should be 1-8 hours.

When administered intravenously, a single dose is 0.5-50 mg. The frequency of administration directly depends on the clinical situation. The maximum that can be administered is 100 mg of the drug per day. If the depot form is taken, then about 300 mg per month. In general, much depends on the person's condition and the disease he suffers from. Haloperidol forte should be taken in strict accordance with the doctor's recommendations.

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Use Haloperidol forte during pregnancy

The use of Haloperidol forte during pregnancy is contraindicated. A similar situation applies to the period of breastfeeding. Thanks to the conducted studies, it was found that in most cases the drug has a teratogenic and fetotoxic effect.

The drug can be excreted with the mother's breast milk. Moreover, its concentration is significant, which can negatively affect the baby's health. It is possible to have a sedative effect and impaired motor functions in the newborn.

If you need to take the product, you should consult a doctor. After all, the consequences of self-use can be serious. It is worth understanding that the child himself suffers to a greater extent.

During breastfeeding, the medicine is not taken; during this period, alternative ways to solve the problem are selected. If a woman becomes pregnant while undergoing an active phase of treatment, the attending physician informs about possible pathologies of the child. Children and pregnant women should never take Haloperidol Forte.

Contraindications

Contraindications to the use of Haloperidol Forte mainly consist of allergic reactions to some components of the drug. This includes people suffering from diseases of the central nervous system. Especially those that are accompanied by extrapyramidal disorders, hysteria, depression and coma.

Severe toxic depression of the central nervous system is also one of the main contraindications. Especially if it is caused by drugs. Lactation and pregnancy do not provide for the use of this medication.

It is not recommended to use the product at the age of up to 3 years. Increased sensitivity to the active component haloperidol is a special risk group. People suffering from such a phenomenon should not take the product. The manifestation of an allergic reaction can be of an extremely complex form. That is why it is not recommended to take the drug on your own. Haloperidol forte can cause serious harm to the body.

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Side effects Haloperidol forte

Side effects of Haloperidol forte manifest themselves in different ways. Thus, from the side of the central nervous system, headache, constant feeling of anxiety or fear, euphoria, constant drowsiness, overexcitement and even an epileptic seizure can be observed.

The cardiovascular system reacts with tachycardia, ECG changes, arrhythmia and alternative hypotension. But this is only possible if too large doses are taken.

Digestive system: dry mouth, nausea, vomiting, constipation or, on the contrary, diarrhea, liver dysfunction. Moreover, the last symptom can lead to the development of jaundice.

In rare cases, leukocytosis, slight erythroenia or a tendency to monocytosis manifest themselves from the hematopoiesis side. The endocrine system reacts in the form of increased libido, menstrual irregularities, and pain in the mammary glands.

Metabolism: increased sweating, significant weight gain, edema and hyponatremia. Visual acuity and accommodation are impaired, cataracts and retinopathy appear.

Allergic reactions in the form of skin rash, hyperpyrexia, laryngospasm and bronchospasm are possible. Hyposalivation and maculopapular changes in the skin are possible. All this can be caused by Haloperidol Forte if used incorrectly.

Overdose

Overdose of Haloperidol forte is not excluded. Thus, this process can manifest itself in the form of acute neuroleptic reactions. In particular, an increase in temperature should be frightening. Often this indicates the presence of malignant neuroleptic syndrome. So to say, this is one of the most basic symptoms of its manifestation.

In severe cases, overdose may lead to impaired consciousness, and coma may occur. If negative reactions occur in the body, treatment should be sought immediately.

Therapy with neuroleptics is suspended, and intravenous administration of diazepam, nootropics, and vitamins B and C is performed. Symptomatic therapy is mandatory.

A person in a pre-fainting state needs to maintain the patency of the respiratory tract. It is imperative to monitor respiratory functions and blood circulation parameters. It is advisable to constantly monitor the condition in case of cardiovascular damage. It is recommended to take diazepam. All these actions will weaken the effect of Haloperidol forte on the body.

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Interactions with other drugs

Interactions with other drugs are not excluded, but in this case, special caution should be exercised. If this medication is taken simultaneously with others that depress the central nervous system, depression may develop. Respiratory depression and hypotensive effects are not excluded. All this requires a doctor's consultation.

During the use of medications that cause extrapyramidal reactions, an increase in the frequency and severity of extrapyramidal effects cannot be ruled out. Drugs with anticholinergic activity can enhance the manifestation of these effects.

The drug should not be taken together with anticonvulsants. In this case, the frequency of epileptiform seizures may change. Haloperidol forte can potentiate the effect of antihypertensive drugs. Together with beta-blockers, arterial hypotension may manifest itself.

Under the influence of the drug, a sharp decrease in the therapeutic effect of levodopa is possible. This occurs due to the blockade of dopain receptors. Simultaneous administration of fluvoxamine can cause an increase in the concentration of the drug in the blood plasma. This is accompanied by a serious toxic effect.

Taking with fluxetine can develop extrapyramidal symptoms and dystonia. An increase in the concentration of Haloperidol forte in the blood plasma is possible.

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Storage conditions

The storage conditions of Haloperidol forte must be observed without fail. The main role in this process is played by the temperature regime. It should not exceed 15-25 degrees. It is clearly not worth exposing the product to freezing. After such exposure, it loses its active properties and is unsuitable for use.

It is advisable to fence off access to the drug. Children are quite curious and they will definitely want to look into the box with pills. Ultimately, the drug can be tasted. For a child's body, such an impact is unacceptable. It is possible to develop pathologies that cannot be corrected.

It is important that the storage place is not exposed to direct sunlight. It is also recommended to exclude moisture. All this has a detrimental effect on the shelf life of the medicine. It is necessary to provide a dry, warm and, most importantly, dark place. Haloperidol forte requires certain storage conditions, because only in this way can its beneficial properties be preserved for a long time.

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Shelf life

The shelf life of the drug is long and is 5 years. Storing the product for such a long time will not be difficult if you follow some rules. So, it is advisable to immediately allocate a dry and warm place for the medicine, where sunlight does not penetrate.

A regular first aid kit will do just fine. The main thing is that it should not be openly accessible to children. Haloperidol forte can have a negative effect on the baby's body and lead to the development of serious problems.

In no case should the medicine be frozen. In this case, it is unacceptable. After cold treatment, the drug may lose all its positive properties. Ultimately, it will not be possible to take it.

Particular attention is paid to the appearance of the tablets. It is indicated that their color does not fluctuate in white and similar tones. If the medicine looks completely different, then most likely the storage conditions were not observed correctly. In this case, Haloperidol forte is not allowed for use and should be removed from the home medicine cabinet.

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