Gripmax Nose

Gripmax Nos is a natural complex drug designed to relieve the symptoms of colds and flu, as well as to maintain the function of the respiratory system. This drug contains a wide range of plant extracts and other natural ingredients, each of which has specific medicinal properties:

1. Bromelain (from Ananas comosus) is an enzyme obtained from the stems and juice of pineapples. It has an anti-inflammatory and mucolytic effect, helps thin mucus and facilitates its discharge.
2. Creeping thyme herb extract (Thymus serpyllum) - known for its antiseptic and antimicrobial properties, helps with coughs and inflammation of the upper respiratory tract.
3. Common ivy leaf extract (Hedera helix L.) - used to treat cough and as a mucolytic agent, helps reduce the viscosity of sputum and ease breathing.
4. Malva sylvestris L. Flower extract - has enveloping and softening properties, helps with irritation of mucous membranes.
5. Purple coneflower herb extract (Echinacea purpurea L. Moench.) - stimulates the immune system, has anti-inflammatory properties, helps fight viral and bacterial infections.
6. Eucalyptus viminalis Labill. Leaf extract - contains eucalyptus oil, which helps cleanse the respiratory tract, has an antibacterial and antiseptic effect.
7. L-ascorbic acid (vitamin C) - supports the immune system, helps reduce the duration and severity of colds.

This medication is intended to be used for the first symptoms of colds and flu such as cough, runny nose, sore throat, and difficulty breathing. It helps reduce inflammation, ease breathing and speed up the healing process.

Indications Gripmax Nose

1. Runny Nose and Nasal Congestion: The herbal extracts of thyme, ivy, mallow and eucalyptus contained in Grippex Nose may help relieve nasal congestion and make breathing easier.
2. Cold and Flu: The product may be used to reduce cold and flu symptoms such as fever, headache, muscle aches and weakness.
3. Immune Booster: Echinacea purpurea (coneflower) herb extract and vitamin C may help strengthen the immune system and make the body more resistant to infections.
4. Cold and flu prevention: Gripaks Nose can also be used as a preventative to reduce the risk of contracting cold and flu viruses.

Release form

Gripmax Nose is usually available in tablet form.

Pharmacodynamics

1. Bromelain (from Ananas comosus): Bromelain is a proteolytic enzyme that has anti-inflammatory and mucolytic properties. It is able to break down mucopolysaccharides in mucus, which helps thin mucus and make expectoration easier.
2. Creeping thyme herb extract (Thymus serpyllum): Creeping thyme has anti-inflammatory, antiseptic and mucolytic properties. It helps reduce inflammation in the airways and ease expectoration.
3. Common ivy leaf extract (Hedera helix L.): Ivy has a mucolytic and expectorant effect, helping to thin and remove mucus from the respiratory tract.
4. Malva sylvestris L. Flower extract: Used as a mild enveloping agent to soothe throat irritation and relieve cough.
5. Purple coneflower herb extract (Echinacea purpurea L. Moench.): Echinacea has immunomodulatory properties and helps strengthen the body's immune system.
6. Eucalyptus viminalis Labill. Leaf Extract: Eucalyptus has anti-inflammatory and expectorant properties, helping to reduce inflammation and ease expectoration.
7. L-ascorbic acid (Vit. C): Vitamin C strengthens the immune system and helps the body fight viral infections such as colds and flu.

Pharmacokinetics

1. Bromelain: Bromelain is usually rapidly absorbed from the gastrointestinal tract. Its metabolism mainly occurs in the liver. It may increase the absorption of certain drugs by increasing their bioavailability.
2. Herbal extracts: Depending on the dosage form (eg drops, spray), herbal extracts can be absorbed through the mucous membrane of the nose and respiratory tract. Their pharmacokinetics may vary depending on the route of administration.
3. Vitamin C (L-ascorbic acid): Vitamin C is usually well absorbed from the gastrointestinal tract and is quickly metabolized in the body. Its elimination occurs mainly through the kidneys.

Dosing and administration

1. Method of application:

   • Shake the bottle well before use.
   • Tilt your head slightly forward and insert the end of the bottle into your nostril.
   • Press the bottle to spray the product into your nose.
   • Inhale with light, deep breaths through your nose as you spray.

2. Dosage:

   • Usually it is recommended to use 1-2 sprays in each nostril.
   • Frequency of use may vary depending on individual needs and your doctor's recommendations. Usually this is no more than 2-3 times a day.

3. Notes:

   • It is important not to exceed the recommended dosage and not to use the drug for longer than recommended.
   • If you have any questions or concerns about the use of Gripmax Nos, be sure to consult your doctor or pharmacist.

Use Gripmax Nose during pregnancy

Information about the safety of using Gripmax Nose during pregnancy may be limited. It is important to consult your doctor or obstetrician/gynecologist before using this drug during pregnancy. They will be able to assess the risks and benefits of using it in your case and make recommendations based on your health and pregnancy. Ingredients such as bromelain, thyme extract, ivy extract, mallow extract, echinacea extract, eucalyptus extract and L-ascorbic acid may have different effects on the body during pregnancy, so it is important to get advice from a qualified healthcare professional.

Contraindications

1. Bromelain (from Ananas comosus):

   • Not recommended for people with a known allergy to pineapple or other fruits of the bromeliad family.
   • There may be restrictions on use in people with gastric or duodenal ulcers.

2. Creeping thyme herb extract (Thymus serpyllum):

   • Thyme is generally considered safe, but people with allergies to plants in the Lamiaceae (mint) family may experience an allergic reaction.

3. Common ivy leaf extract (Hedera helix L.):

   • Ivy may cause an allergic reaction in some people.
   • Not recommended for use in pregnant or breastfeeding women without consulting a physician.

4. Malva sylvestris L. Flower extract:

   • Usually well tolerated, but some people may experience an allergic reaction.

5. Echinacea purpurea L. Moench. Herb extract:

   • May cause allergic reactions in people with allergies to plants in the asteraceae family.

6. Eucalyptus viminalis Labill. Leaf extract:

   • Eucalyptus may cause an allergic reaction in some people.
   • Not recommended for use in children under 6 years of age without medical advice.

7. L-ascorbic acid (vitamin C):

   • Contraindications are limited. However, taking large doses of vitamin C can cause stomach upset.

Side effects Gripmax Nose

1. Bromelain (from Ananas comosus):

   • May cause allergic reactions in those allergic to pineapple.
   • In rare cases, may cause gastrointestinal problems such as diarrhea or stomach discomfort.

2. Creeping thyme herb extract (Thymus serpyllum):

   • Due to its antiseptic properties, may cause irritation of mucous membranes in some people.

3. Common ivy leaf extract (Hedera helix L.):

   • May cause skin reactions or irritation upon contact with skin or mucous membranes.
   • In rare cases, may cause breathing problems, especially in people with asthma.

4. Malva sylvestris L. Flower extract:

   • Usually well tolerated, but may cause allergic reactions in sensitive people.

5. Echinacea purpurea L. Moench. Herb extract:

   • May cause allergic reactions, especially in persons allergic to other plants in the Asteraceae family.
   • Long-term use is not recommended as it may reduce the effectiveness of the immune system when taken over long periods of time.

6. Eucalyptus viminalis Labill. Leaf extract:

   • May cause throat or respiratory irritation, especially if oil is inhaled in large quantities.

7. L-ascorbic acid (vitamin C):

   • Well tolerated in normal doses, but in high doses may cause stomach upset, diarrhea, or kidney stones.

Overdose

1. Bromelain: An overdose of bromelain may cause diarrhea, nausea, vomiting, allergic reactions, or increased inflammation in the mouth.
2. Creeping thyme herb extract: Possible side effects, such as allergic reactions or diarrhea.
3. Common ivy leaf extract: Overdosing with ivy may result in rare adverse effects such as nausea, vomiting, diarrhea or allergic reactions.
4. Mallow flower extract: Overdose may cause drowsiness, dizziness, or gastrointestinal upset.
5. Echinacea purpurea herb extract: Possible allergic reactions or gastrointestinal disorders.
6. Eucalyptus rodentum leaf extract: Overdose may cause nausea, vomiting, diarrhea or allergic reactions.
7. L-ascorbic acid (Vit. C): An overdose of vitamin C can lead to diarrhea, gastrointestinal upset, vomiting, allergic reactions, or even kidney stones in those with high levels of oxalate in the urine.

Interactions with other drugs

1. Ascorbic acid (vitamin C):

   • Interaction with aspirin (acetylsalicylic acid): Vitamin C may increase the elimination of aspirin from the body and reduce its effectiveness.
   • Interaction with amphetamines: Vitamin C can increase the acidity of urine, which reduces the resorption of amphetamines and increases their excretion from the body.
   • Interaction with aluminum, iron and zinc: Vitamin C may increase their absorption in the gastrointestinal tract.

2. Echinacea purpurea herb extract:

   • Interaction with immunosuppressive drugs: Echinacea may enhance the immune response and reduce the effectiveness of immunosuppressive drugs.

3. Eucalyptus twig leaf extract:

   • Interaction with blood sugar medications: Eucalyptus may increase blood sugar levels and reduce the effectiveness of blood sugar medications.

4. Common ivy leaf extract:

   • Interaction with anticoagulants: Ivy may enhance the effect of anticoagulants and increase the risk of bleeding.

5. Creeping thyme herb extract:

   • Interaction with sedatives: Thyme may increase the sedative effects of some medications, such as benzodiazepines.

6. Mallow flower extract:

   • Interaction with antihypertensive drugs: The use of mallow can enhance the hypotensive effect of antihypertensive drugs, which can lead to an excessive decrease in blood pressure.

7. Bromelain (from Ananas comosus):

   • Interaction with anticoagulants: Bromelain may enhance the effect of anticoagulants and increase the risk of bleeding.