Fervex

Fervex has analgesic, antihistamine and antipyretic effects.

Indications Fervex

It is used to eliminate the manifestations of ARVI, as well as the treatment of rhinopharyngitis.

Release form

The release is made in the form of powder, in bags of 13.1, and also 4.95 g. Inside the box there are 8 such bags.

In addition, it is sold in the dosage form for children - in bags of 3 g, in the amount of 8 pieces inside the package.

Pharmacodynamics

The drug acts due to the activity of its constituent elements.

Paracetamol has antipyretic and analgesic properties, affecting the central thermoregulation processes inside the hypothalamus. As a result, there is a decrease in temperature, as well as the elimination of headaches and other pains.

Vitamin C regulates the processes of oxidation-reduction, production of corticosteroids, tissue healing, blood coagulation, and in addition carbohydrate metabolism and the formation of collagen with procollagen. It also helps to stabilize the strength of capillaries. The use of this vitamin increases the protective function of the body (by stimulating immune reactions).

The pheniramine component blocks the activity of histamine H1-terminations. It helps relieve symptoms of rhinorrhea, nasal congestion, sneezing with lacrimation, and besides, itching and redness in the eye area.

Pharmacokinetics

Penetrating the inside, the medicine is fully and at high speed absorbed, reaching its Cmax indices after 0.5-1 hour from the moment of administration.

The drug is well distributed inside the physiological fluids and tissues, and in addition it passes through the BBB. Protein synthesis is extremely weak. Exchange processes occur in the liver; at the same time non-active metabolic products are formed.

Excretion of drug components occurs through the kidneys.

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Dosing and administration

The drug is administered orally. The powder contained in the bag must be completely dissolved in a glass of water, and then immediately drink the resulting liquid. It is recommended to take medicine in intervals between meals.

Apply Ferveks need in the amount of 1 sachet, a maximum of 2-3 times per day. There must be a 4-hour gap between receptions. In individuals with impaired hepatic function and the elderly, this gap is 8 hours.

The therapeutic cycle can last a maximum of 5 days.

Children also take the medicine orally - the powder is first dissolved in 0.2 l of plain water.

It is necessary to pick up a portion of drugs, given the age of the child. Thus, children in the age range of 6-10 years old should drink 1 sachet 2 times a day. Children 10-12 years old take 1 sachet of drugs 3 times a day, and 12-15-year-olds need to use the first sachet of the substance a maximum of 4 times a day.

The intervals between drug intake in children should be 4 hours. The duration of such treatment is a maximum of 3 days.

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Use Fervex during pregnancy

It is revealed that pregnant women can use the drug exclusively in the 2nd trimester. It is prohibited to use it during the 1st and 3rd trimesters.

Do not use Ferveks during breastfeeding.

Contraindications

Among the contraindications:

• the presence of intolerance against the drug;
• ulcers or erosion inside the digestive tract;
• renal failure;
• alcoholism;
• portal hypertension;
• lack of G6FD enzyme.

Children should not be prescribed in such cases:

• the presence of hypersensitivity to the drug;
• disorders of the kidney or liver in severe;
• lack of G6FD enzyme;
• blood pathology.

Extremely careful medication should be used for diabetics, as well as for people with hyperbilirubinemia of a benign nature.

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Side effects Fervex

The use of the drug rarely leads to the appearance of adverse symptoms (in the case of compliance with the required size dosages). But sometimes such reactions as abdominal pain, nausea and signs of allergy (itching, rash, angioedema and urticaria) may still occur.

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Overdose

Long-term use of Ferveksa in high dosages can cause the development of signs such as poor appetite, vomiting, pallor of the epidermis, nausea and hepatonecrosis. Occasionally, liver failure also appears.

To eliminate violations, standard procedures are performed — gastric lavage, the introduction of donators of the SH categories or precursors of glutathione-methionine production (after 8–9 hours from the moment of poisoning).

In situations where overdose lasts 12 hours, you need to use N-acetylcysteine. At the same time, other related procedures are performed, depending on the developed signs of violations.

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Interactions with other drugs

Combination with antipsychotics, antidepressants, and also antiparkinsonian drugs can lead to an increased likelihood of developing negative symptoms.

Combination with means that induces hepatic oxidation of microsomes (barbiturates, phenytoin, phenylbutazone with rifampicin, as well as tricyclics), can lead to an increase in the production of hydroxylated metabolic products, as a result of which severe poisoning may develop.

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Storage conditions

Fervex is required to be kept in a closed and dry place from children’s access.

Shelf life

Fervex can be used within 36 months from the date of manufacture of the pharmaceutical product.

Application for children

Standard Ferveks is forbidden to use to children up to 15 years of age, and children - to persons under the age of 6 years.

Analogs

Analogues of the medicament are Sinupret, Bioparox, and Coldrex with Theraflu.

Reviews

Fervex receives a large number of responses in various medical forums. Patients note that by using this medication immediately after the onset of the first symptoms of a cold, the progression of the disease can be quickly prevented. But at the same time, great importance is attached to other factors - good rest with bed rest, as well as abundant fluid intake. Compliance with these conditions allows the body to support and strengthen its immune defenses against the virus.

The children's form of a medicinal product that can be prescribed to a child over 6 years old is often discussed. At this age, children are more willing to use sweet syrups, suspensions and solutions than tablets, so parents respond positively to the drug. In this case, the drug effect also has the maximum severity in the case of its use in the development of the first manifestations of pathology.

In addition to positive reviews, there are also comments in which side effects of drugs are noted — the feeling of drowsiness is most often distinguished (although this effect is often observed in infections of viral genesis by itself).

At the same time, there are opinions of those people who claim that the drug had absolutely no effect. After several days of treatment, the symptoms of a cold not only did not become less pronounced, but, on the contrary, increased. Potentiation of inflammation inside the throat, headaches and aches in the muscle area were also observed.

It should be understood that quite a few people treat colds as something not very serious, and therefore do not bother with their treatment. Attempts are mainly made to stifle the manifestations that have arisen, but as a result, complications are often developed that require more serious therapy, sometimes with antibiotics.

In this regard, experts recommend in the absence of improvements after 2-3 days of taking the drug, immediately contact the doctor, who will conduct an additional examination and select the most appropriate medication and treatment regimen.