Diseases of the blood (hematology)

Diseases of eosinophils: causes, symptoms, diagnosis, treatment

Eosinophils are granulocytes and are derived from the same precursor as monocyte-macrophages, non-atrophils and basophils. The exact function of eosinophils is unknown. As phagocytes, eosinophils are less effective than nontrophils in the destruction of intracellular bacteria.

Spleen rupture

Spleen rupture is usually the result of blunt abdominal trauma. The increase in the spleen as a result of fulminant infection caused by the Epstein-Barr virus (infectious mononucleosis or posttransplantation pseudolymphoma) predisposes to rupture from minimal trauma or even spontaneous rupture. A significant impact (for example, a car accident) can lead to the rupture of even a normal spleen.

Hyperplenism: causes, symptoms, diagnosis, treatment

Hypersplenism is a syndrome of cytopenia caused by splenomegaly. Hypersplenism is a secondary process that can be caused by splenomegaly caused by a variety of causes. Treatment is aimed at the underlying disease. However, if hypersplenism is the single most serious manifestation of the disease (eg, Gaucher's disease), ablation of the spleen can be indicated by splenectomy or radiotherapy.

Splenomegaly

Splenomegaly is almost always secondary to other diseases, which are very many, as well as possible ways to classify them. Myeloproliferative and lymphoproliferative diseases, accumulation diseases (eg, Gaucher's disease) and connective tissue diseases are the most common causes of splenomegaly in temperate countries, while infectious diseases (eg malaria, kala-azar) prevail in the tropics.

Diseases of the spleen and bleeding

In structure and function, the spleen resembles two different organs. White pulp, consisting of periarterial lymphatic membrane and germinal centers, functions as an immune organ. Red pulp, consisting of macrophages and granulocytes lining the vascular space (chords and sinusoids), functions as a phagocytic organ.

Senile purpura: causes, symptoms, diagnosis, treatment

Senile purpura leads to the appearance of ecchymoses and is the result of increased fragility of the vessels caused by damage to the connective tissue of the skin caused by chronic insolation and age.

Simple purpura: causes, symptoms, diagnosis, treatment

Simple purple - increased formation of hematomas, resulting from the fragility of the vessels. Simple purple is extremely common. The cause and mechanism of this pathology are unknown. It can manifest itself in various diseases.

Congenital hemorrhagic telangiectasia (Rundu-Osler-Weber Syndrome)

Congenital hemorrhagic telangiectasia (Randu-Osler-Weber Syndrome) is a hereditary disease with vascular disruption, which is inherited in an autosomal dominant type and is found in both men and women.

Rare diseases, accompanied by bleeding

Bleeding can be the result of platelet abnormality, coagulation factors and blood vessels. Diseases of the bleeding of the vessels are caused by the pathology of the vascular wall and are usually manifested by petechiae, purpura, but rarely cause serious bleeding.

Hemophilia: causes, symptoms, diagnosis, treatment

Hemophilia is usually a congenital disease caused by deficiency of factors VIII or IX. The severity of factor deficiency determines the likelihood of development and severity of bleeding. Bleeding in soft tissues or joints usually develops within a few hours of trauma.

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