The consequences of lymphopenia include the development of opportunistic infections and an increased risk of cancer and autoimmune diseases. If lymphopenia is detected when performing a general blood test, diagnostic tests should be performed for immunodeficient states and analysis of lymphocyte subpopulations. The treatment is aimed at the underlying disease.
Neutropenia (agranulocytosis, granulocytopenia) is a decrease in the number of blood neutrophils (granulocytes). In severe neutropenia, the risk and severity of bacterial and fungal infections increase.
Because of the high incidence of thalassemia HbS and beta-thalassemia in certain population groups, the congenital presence of both anomalies is quite frequent.
Symptoms and complaints are caused by the development of anemia, hemolysis, splenomegaly, bone marrow hyperplasia and multiple transfusions with iron overload. The diagnosis is based on a quantitative analysis of hemoglobin.
Hemoglobin E is the third most frequent occurrence of hemoglobinopathy (after HbA and HbS), it occurs mainly in Negroid and American people and people from Southeast Asia, while among Chinese it is rare.
Sickle-cell anemia (hemoglobinopathy) is a chronic hemolytic anemia, occurring predominantly in blacks in America and Africa, due to homozygous inheritance of HbS
Deficiency of glucose-6-phosphate dehydrogenase (G6PD) is X-linked fermentopathy, is more common in people of negroid race, hemolysis can occur after acute illness or intake of oxidants (including salicylates and sulfonamides).
