Digestal

Digestal is a complex enzyme medicine that compensates for the lack of biliary and pancreatic enzymes, as well as helps to improve digestive activity.

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Indications Digestals

Used for these disorders:

• insufficiency of exocrine pancreatic activity (diseases such as chronic pancreatitis or cystic fibrosis);
• intestinal or gastric pathologies and gallbladder diseases that are inflammatory and dystrophic in nature and occur chronically (conditions that develop in connection with the irradiation or resection of these organs, against which food digestion disorders, bloating and diarrhea appear ) - along with other medicines;
• during preparation for performing an ultrasound or x-ray in the area of the peritoneal organs;
• the presence of errors in the diet, and in addition to this disorder of chewing activity, prolonged forced immobility and a sedentary, inactive way of life (to improve the food digestion in people without disorders in the digestive tract).

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Release form

The release of the substance is made in the form of dragees, inside the cell plates, in the amount of 10 pieces. The box contains 3 such records.

In addition, it is sold in tablets, 10 or 20 pieces inside blisters. The pack contains 3 blisters.

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Pharmacodynamics

Active elements of the drug compensate for the failure of hepatic biliary activity, as well as pancreatic excretory activity. Enzymes (protease and amylase with lipase) contained in pancreatin help to facilitate the digestion of fats with carbohydrates and proteins, making them more fully absorbed inside the small intestine.

The hemicellulose enzyme helps to activate the breakdown of plant fiber, which also improves the digestive function and decreases intestinal gas formation.

Bile extract has choleretic activity. It helps the pancreas to secrete lipase and facilitates the process of digesting fat.

Dosing and administration

The drug must be swallowed whole, without chewing pill / dragee. It is recommended to use the substance with food or after it.

Digestal should be applied according to the following schemes:

• Adult pills need to be consumed 3 times a day, in the amount of 1-3 pieces (higher portions are required to be agreed with the doctor). Children's dosages are selected by the doctor, personally;
• pills consume an average of 1-2 pieces per day.

The duration of treatment depends on the prescribed indications and varies from several days (digestive disorders, associated with errors in the dietary regimen) to several months or years (use in the form of regular replacement treatment).

Use Digestals during pregnancy

It is not recommended to use Digestal when breastfeeding or pregnancy, because there is not enough clinical information about the use of drugs during these periods.

This category of patient medication is prescribed only in situations where the likely benefit is more expected than the risk of adverse effects.

Contraindications

Among the contraindications:

• acute stage of pancreatitis;
• holelitiaz;
• acute pancreatitis of a chronic nature;
• hepatitis;
• liver failure;
• the mechanical form of jaundice;
• the presence of hypersensitivity with respect to drug substances.

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Side effects Digestals

Drug administration can cause the following side effects:

• digestive disorders: weakening of the endogenous binding of bile acids. Prolonged use in large portions leads to hyperuricuria or an increase in plasma indicators of uric acid;
• other disorders: allergy symptoms.

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Interactions with other drugs

Combined administration with iron medications can lead to a weakening of their absorption.

The combination with calcium or magnesium-containing antacids may be the reason for the reduction of the therapeutic activity of Digestal.

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Storage conditions

The digestal is required to be kept in a dry and dark place closed from small children. Temperature marks - up to 15 ° C (for tablets) and 25 ° C (for pills).

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Shelf life

Digestal can be used within a 24-month period since the release of the tablets. Shelf life dragee is 36 months.

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Analogs

Analogues of the drug are the substances Digestin, Penzital, Pepzym, Forestal with Enzibene, and in addition Panzinorm, Agizim, Ipental with Panenzyme and Pangrol with Festal. The list also includes Micrasim, Enzistal, Mezim forte, Pancreatin, Creon and Pancreasim with Hermital and Panzitrat, as well as Unianzyme, Forte enzyme and so on.

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Reviews

Digestal is considered to be a rather effective medicine that deals with the disorders it is intended to treat. The reviews also note the rarity of the onset of negative symptoms and the relatively low cost of the drug (compared to others from this therapeutic group).