Desmistine

The external drug Desmistin is a dermatological antiseptic, which is actively used for the treatment and prevention of skin infectious diseases, including on wound and burn surfaces.

Desmistin is available in pharmacies without a prescription.

Indications Desmistine

• As a preventive measure against purulent infection in wounds.
• For the treatment of traumatic inflammatory and purulent reactions of the musculoskeletal system.
• As a therapy and prevention of infection of obstetric injuries, inflammatory processes of the genital organs.
• For the treatment of burns of the second and third A degrees.
• To prepare burn surfaces for plastic surgery.
• As a treatment and prevention of infectious, purulent and fungal lesions of the skin and mucous membranes.
• As a preventive measure to reduce the likelihood of contracting sexually transmitted infections (syphilis, chlamydia, thrush, trichomonas, etc.).
• For the treatment of inflammatory processes of the urethra and prostate.

Release form

Desmistin is produced as a solution for topical use and is a clear liquid, without a specific color or odor. It may foam when shaken.

Desmistin includes:

• active ingredient – miramistin (10 ml of liquid contains 10 mg of the active ingredient);
• additional component – purified water.

The drug is available in polymer bottles, 100 ml of solution per bottle.

Pharmacodynamics

The active component of the drug is known for its extensive bactericidal action, directed even against those microorganisms that do not respond to most antibiotics.

Desmistin has a destructive effect on bacteria:

• gram (+) – staphylococci and streptococci;
• gram (-) – Escherichia, Klebsiella, Pseudomonas, etc.;
• aerobes and anaerobes (monocultures and bacterial strains);
• fungal infection – ascomycetes, yeast and yeast-like fungi, dermatophytes and other pathogenic fungi, including those resistant to antifungal agents;
• viral infection – complex viruses (herpes pathogen, immunodeficiency, etc.);
• sexually transmitted infections – chlamydia, treponema, trichomonas, gonorrhea pathogens, etc.

Desmistin is an excellent preventative measure against infection of wound and burn surfaces, stimulates tissue regeneration. Increases local immunity by enhancing the activity and capabilities of the phagocytic system, activates the activity of macrocytes and macrophages. Refers to drugs that create high osmotic pressure in wounds, as a result of which the inflammatory process is eliminated, exudative fluid (pus) is removed from the wound, and a dry crust forms faster. Desmistin does not have a negative effect on granulation and healthy tissues, does not interfere with border epithelialization.

Does not cause allergies and does not irritate the skin and mucous membranes.

Pharmacokinetics

External use of Desmistin prevents the drug from penetrating through the skin and mucous membranes into the systemic circulation.

Dosing and administration

To disinfect hands, use up to 10 ml of liquid, applying it to clean and dry hands. The preparation is distributed over at least 5 minutes over all skin of the hands.

Irrigation of wound and burn surfaces with a 0.1% solution of Desmistin is used as a preventive and therapeutic measure. The solution can also be used for tampons and lotions. Such procedures are carried out up to 3 times a day. Duration of treatment is 4-5 days.

For purulent and fungal infectious lesions, infected wound surfaces, cutaneous candidiasis, mycosis of the feet and skin folds, the solution of the drug is used for washing and lotions.

In case of minor household injuries (cuts, abrasions and abrasions), the skin area at the site of injury is wiped with a solution of the preparation or a napkin soaked in the solution is applied. The procedures can be repeated up to 3 times a day for 4-5 days.

Use Desmistine during pregnancy

Desmistin is approved for use by pregnant women, as it does not have the ability to penetrate into the systemic circulation when applied externally, and, accordingly, cannot have any effect on either the development of the fetus or the course of pregnancy.

There is no information on the effects of Desmistin during breastfeeding, nor is there any data on whether the drug penetrates into breast milk. However, there were no negative reviews on the use of the external agent by nursing women.

Contraindications

Desmistin is a hypoallergenic drug, but the possibility of hypersensitivity to the active component miramistin cannot be ruled out.

If you are prone to allergic reactions to miramistin, the drug is not prescribed.

Side effects Desmistine

Side effects of Desmistin are extremely rare. A slight tingling or burning sensation may occur, which disappears on its own 20 seconds after applying the solution. This condition is not a reason to stop taking Desmistin.

In rare cases, allergic reactions to the drug may occur. Treatment is symptomatic.

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Overdose

There have been no cases of overdose with the external drug Desmistin.

Interactions with other drugs

When used in combination with other antimicrobial and antifungal drugs, Desmistin solution enhances their effectiveness.

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Storage conditions

Desmistin solution is stored at normal room temperature (on average 20-25°C), in places inaccessible to children.

Shelf life

Shelf life: up to 3 years.