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Health

Darcy

, medical expert
Last reviewed: 09.08.2022
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Darcil is a hepatoprotector that protects, promotes the treatment and recovery of the liver. 

Indications Darcy

Darsil is prescribed for liver damage by toxic substances, as well as inflammatory processes in the liver and cirrhosis as part of complex therapy. 

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Release form

Darsil is available in the form of tablets. 

Pharmacodynamics

Active component of Darsil is silymarin - a complex of flavonoids that fight in the liver with free radicals, do not allow to destroy cells, restore the hepatocyte membranes.

The drug promotes the synthesis of proteins in damaged hapatocytes, cell regeneration, prevents the loss of cellular elements.

In addition, Darsil inhibits the penetration of toxic substances for the liver (including poison pale toadstool). 

The drug improves the overall well-being of patients, eliminates (or significantly reduces) a sense of weakness, pain in the hypochondrium, normalizes the functional state of the body. 

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Pharmacokinetics

Darsil has a low absorption, binding to blood proteins does not occur. The drug undergoes biotransformation in the liver, takes part in connective reactions, in which sulfates and glucuronides are formed.

Removal of the drug from the body is mainly a gallbladder, in the small intestine is absorption into the systemic circulation. The half-life is about 6 hours. The preparation practically does not accumulate in the body. 

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Dosing and administration

The medication is taken after a meal, the tablets can not be chewed or broken, it is better to drink better with a small amount of water.  

Adults are usually given 1-2 tablets three times a day, children 5-12 years are prescribed 3 mg of silymarin per 1 kg of weight (the dose should be divided into several doses). Duration of admission is determined by the doctor, given the severity of the disease, on average, the drug is taken for three months. 

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Use Darcy during pregnancy

Darcil was not tested on pregnant and breastfeeding women. 

Contraindications

Darsil is contraindicated in case of increased susceptibility of the organism to the components of the drug, with exacerbation of chronic stomach diseases, acute poisoning, and also the drug is not prescribed for children under 5 years. 

Side effects Darcy

Darcil can cause headaches, indigestion, bloating, heartburn, nausea, upset of the stool.

In some cases, against the background of treatment with the drug, shortness of breath, joint pain, a decrease in the volume of urine, rashes on the skin, hair loss.

All adverse reactions after the drug cancellation pass by themselves. 

trusted-source[8], [9], [10], [11], [12]

Overdose

In the study of Darcil, there were no cases of overdose. In case of any symptoms of an overdose (nausea, vomiting, dizziness), symptomatic treatment (sorbent intake, gastric lavage) is required.


 

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Interactions with other drugs

Darsil has the ability to enhance the therapeutic effect of antiallergenic, antifungal, hypocholesterolemic drugs, anticoagulants, antipsychotics. 

Darsil with simultaneous intake reduces the effectiveness of oral contraceptives and the means used for hormone replacement therapy. 

trusted-source[19], [20], [21], [22], [23], [24]

Storage conditions

Darsil must be stored in a dry place, protected from sunlight, the storage temperature should not be above 25 ° C.

Shelf life

Darsil is 24 months from the date of manufacture, the medication is not used after the expiry date or when the storage conditions are violated.

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Attention!

To simplify the perception of information, this instruction for use of the drug "Darcy" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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