Medical expert of the article
New publications
Preparations
D-Panthenol
Last reviewed: 03.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
D-Panthenol is a multifunctional drug. The medicine is used for injuries and skin damage, scratches and painful calluses, burns, diaper rash, for moisturizing and healing. D-Panthenol is available in the form of an ointment and cream. D-Panthenol is a panacea for minor skin problems and much more. Let's find out more information about D-Panthenol, its use, side effects and interaction with other drugs. Regardless of the form of release, the medicine is used for skin problems. Let's take a closer look at what D-Panthenol can help with.
- Skin dermatitis, both in adults and infants.
- Cracked nipples - this problem is mainly faced by pregnant women and women who actively engage in sports, especially swimming (due to chlorinated water).
- Disorders of the mucous membrane of the cervix - the drug allows you to restore the integrity of the cervix and relieve the pain that bothers the woman.
- Scratches and abrasions - D-Panthenol has an anti-inflammatory effect, the drug is an excellent antiseptic, which prevents the possibility of suppuration of any wound.
- Burns of any degree - D-Panthenol stimulates cell growth and promotes rapid restoration of the skin.
- Anal fissures.
- Helps treat the negative effects of exposure of unprotected skin to wind, cold and high humidity.
In addition, the substance is also used for preventive purposes. So, if it is cold or very windy outside, it is recommended to treat sensitive areas of the skin that will be exposed to bad weather.
Indications D-Panthenol
The main indications for use are:
- Skin problems
- Violation of the integrity of the skin
- Burns, including sunburns
- Dermatitis, abrasions, scratches
- Trophic ulcers, furuncles, abscesses
- Bedsores, postoperative wounds
- Cervical erosion
- Poorly grafted skin
- Cracks and inflammation of the nipples during lactation, pregnancy
- Diaper rash in infants
- Diaper rash
- Sunburn in Children
- Inflammatory processes
- Prevention and treatment of adverse environmental effects on the skin (wind, cold, high humidity).
Release form
The product is available in two forms: cream and ointment.
Ointment – 5%, available in an aluminum tube with a sealed opening, dosage of 25 and 50 grams.
Main properties of the ointment:
- It is used for treating skin after surgical interventions and aseptic surgical wounds.
- Helps with skin grafts and skin transplants, as well as bedsores.
- Treats trophic ulcers, irritations from ultraviolet and X-ray radiation.
- Helps with any skin inflammations and boils.
- Indispensable when caring for small children, as it is an excellent preventative for diaper dermatitis and diaper rash.
- It is necessary for treating dry and dehydrated skin in both adults and children.
Cream – 5%, available in an aluminum tube with a sealed opening, dosage of 25 and 50 grams.
Main properties of the cream:
- Prevention of diaper rash in children and adults
- Treatment for mild diaper rash.
Pharmacodynamics
Pharmacodynamics allows to determine the localization and mechanisms of active substances of the drug, as well as their significance and effects when exposed to various factors. D-Panthenol is a drug that helps improve tissue regeneration abilities and is used for external use.
Dexpanthenol is a derivative of panthenic acid, which is a water-soluble vitamin of group B. This substance is necessary for fat, carbohydrate and protein metabolism of the skin. The substance plays an important role in gluconeonesis and acetylation processes. It helps to release energy from carbohydrates, promotes the breakdown and synthesis of fatty acids, the synthesis of steroid hormones, the synthesis of sterions and acetylcholine.
To maintain normal epithelial functions, the pharmacodynamics of D-Panthenol is represented by pantothenic acid. When the skin and tissues are damaged, the body experiences a shortage of this substance. Pantothenic acid in D-Panthenol stimulates skin regeneration, increases the strength of collagen fibers and normalizes metabolism at the cellular level. It also has anti-inflammatory, moisturizing and regenerating properties. Excipients that are part of the ointment and cream significantly improve the therapeutic properties of D-Panthenol.
Pharmacokinetics
Pharmacokinetics allows you to accurately assess the dynamics and stay of a drug and its metabolites in the body. That is, the pharmacokinetics of a drug allows you to study medicinal substances, due to the effect of which you can develop an accurate dosing method and duration of use of the drug.
Low molecular weight and low polarity make it possible for the drug to affect all layers of the skin when it penetrates. Thus, when D-Panthenol is applied locally, the drug is absorbed very quickly and becomes pantothenic acid, which is bound to plasma proteins. When D-Panthenol is applied, the drug is absorbed very quickly through the mucous membrane and skin, penetrates into damaged tissues and promotes increased metabolism of pantothenic acid.
Dosing and administration
The method of application and dosage of the medicine depend on the disease that D-Panthenol should cure. Thus, for the treatment of dermatitis, diaper rash, bedsores, mucous membrane defects and when caring for the mammary glands, D-Panthenol ointment or cream is used one or more times a day, depending on the doctor's recommendations and the complexity of the disease. If D-Panthenol is used to treat cracks in the nipples of the breast, then it is necessary to make compresses and ointments.
As for the choice of cream or ointment for use, everything is determined by the nature and characteristics of the surface to which the medicinal D-Panthenol is applied. So, for dry skin, ointment is recommended, as it contains a high percentage of fat and is used to treat cracks in the skin and dry skin. But for wet wounds and burns, it is recommended to use cream, as it does not contain fat. The cream is very easy to rub in, so it is convenient for use in painful burns.
Doses of D-Panthenol - the substance is applied in a thin layer to the affected area, two to four times a day. If the ointment is used on an infected surface, it is recommended to treat the affected area with an antiseptic before using D-Panthenol. Nursing mothers should lubricate the nipples of the breast after each feeding of the baby to prevent the formation of wounds and cracks on the chest. But infants should be smeared with D-Panthenol after water procedures and each change of linen.
[ 15 ]
Use D-Panthenol during pregnancy
Use during pregnancy is absolutely safe and permitted. The drug does not have a negative impact on the development of the child, either in the early stages of pregnancy or in the last months of gestation.
The only caution that pregnant women should take when using the substance is individual intolerance to the substances that are part of the drug. But do not forget that any use of drugs is not recommended during pregnancy, so if possible, replace D-Panthenol with safe treatment using traditional medicine methods.
Contraindications
Contraindications for use are based on intolerance to substances that are part of the drug. Also, the use of the substance is contraindicated in case of hypersensitivity to dexpanthenol, auxiliary components of the drug and pantothenic acid.
[ 12 ]
Side effects D-Panthenol
Side effects are very rare, this happens with individual intolerance to the drug. The drug can provoke local allergic reactions.
Also, side effects include:
- The appearance of itching
- Small rash on the skin
- Skin dermatitis
- Erythema
- Eczema
- Hives
In medical practice, there have been isolated cases where the use of D-Panthenol caused side effects.
Overdose
Overdose may cause a short-term and minor allergic reaction. But due to low absorption, i.e. the drug's absorption into the skin, overdose is impossible.
Theoretically, if you take a large amount of the drug internally, it can cause dyspepsia. In this case, symptomatic treatment is provided, that is, the whole process is reversible.
[ 16 ]
Interactions with other drugs
Interaction with other drugs is allowed. However, special attention should be paid to the components of the interacting drugs. Since the slightest intolerance to any substance can cause a severe allergic reaction.
To prevent this from happening, before using D-Panthenol with other drugs, consult your doctor about drug interactions and reactions to your body.
Storage conditions
Storage conditions are standard for drugs of this group. The drug should be stored in a place inaccessible to children and in a place protected from high humidity.
One of the storage conditions for D-Panthenol is compliance with the temperature regime. The temperature should not be higher than 25 degrees Celsius. Also, the drug should be stored away from light and direct sunlight.
Shelf life
The shelf life of D-Panthenol, which is set by the manufacturer, for the ointment form of the drug should not exceed 2 years, and for the cream - no more than 18 months.
As soon as the medicine begins to change its color or consistency, it must be disposed of. Since this indicates that D-Panthenol has lost its medicinal properties due to an expired shelf life or improper storage conditions of the drug.
[ 21 ]
Attention!
To simplify the perception of information, this instruction for use of the drug "D-Panthenol" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.