Cereton

Nootropic drug, belongs to the group of cholinomimetics with a central mechanism of action.

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Indications Ceretona

It is used for therapy in patients who are in the recovery stage after severe craniocerebral injuries, ischemic or hemorrhagic stroke. It is also used in the treatment of psychoorganic syndrome, senile pseudo-melancholia, and cognitive disorders.

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Release form

This drug is available in two forms: capsules and a solution used for injections. The oval gelatin capsules are slightly yellowish-brown in color. Inside them is a transparent or translucent liquid of an oily appearance.

The solution is used to prepare intramuscular and intravenous injections. It is completely transparent.

The active ingredient in the preparation is choline alfoscetate. Additional components included in the preparation are: purified water and glycerol.

Pharmacodynamics

Cereton is a nootropic. It has a metabolic effect by releasing choline in the brain. Choline ensures the synthesis of two important substances (phosphatidylcholine and acetylcholine) that are found in neuronal membranes, and improves metabolic processes that occur in the central nervous system. On the side of the brain that was damaged, blood flow increases significantly. There is also an improvement in the spatial and temporal characteristics of bioelectrical activity in the brain. The patient's consciousness is restored, and the patient's behavioral and cognitive reactions improve.

It has a corrective and preventive effect on involutional psychoorganic syndrome, reducing the cholinergic activity of neurons and changing the amount of phospholipids in their membranes. It participates in the synthesis of membrane phospholipids, thereby improving synaptic transmission and their plasticity.

Pharmacokinetics

The absorption of the drug is 88%. It penetrates the blood-brain barrier quite easily. If taken orally, the concentration of choline in the brain is 45%. The accumulation of the drug occurs in the lungs, brain and liver.

The lungs excrete 85% of the drug in the form of carbon dioxide, 15% of the drug is excreted through the intestines and kidneys.

Dosing and administration

If the drug is used for prevention or recovery after traumatic brain injury, hemorrhagic or ischemic stroke, then the dosage is as follows: 800 mg of the drug in the morning, 400 mg of the drug in the daytime. Duration - six months.

For other diseases, Cereton is used at 400 mg three times a day. Best after meals. Duration of therapy is from three to six months.

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Use Ceretona during pregnancy

Pregnant women and those who are breastfeeding are strictly prohibited from using this drug.

Contraindications

The drug "Cereton" cannot be used in the following diseases and symptoms:

1. When the patient is in the acute stage of hemorrhagic stroke.
2. Intolerance to the components of the drug.
3. The patient's age is under eighteen years.
4. Pregnant women and women who breastfeed.

Side effects Ceretona

1. Nausea, possibly vomiting. For treatment it is necessary to reduce the dosage of the drug.
2. Allergy (rash, itching, burning).

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Overdose

In case of overdose of this drug, the patient experiences very severe nausea, which must be treated with symptomatic therapy.

Interactions with other drugs

No significant interactions with other drugs were identified.

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Storage conditions

This product is on the B list, it is recommended to store it in a place that is inaccessible to small children. It is important that the place is completely protected from direct sunlight. The air temperature should not exceed +25 degrees.

Shelf life

It is valid for three years. It cannot be used after this period.