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Ceregin
Last reviewed: 23.04.2024
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Neuroprotective agent. It is used to treat disorders of cerebral circulation. The drug positively affects the intracellular metabolism, protects the brain cells from the negative effects of toxic substances, and also has a neuromodulatory effect.
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Indications of the ceregin
The indications for Ceregin are as follows:
- Ischemic stroke (in acute phase and during rehabilitation period).
- Decreased memory, mental performance.
- Intellectual failure.
- Disorders of thinking.
- Dissipation.
- Cerebrovascular insufficiency.
- Senile dementia.
- Post-traumatic states of the brain (lesions of the skull and its contents due to trauma, rehabilitation post-operation period due to the surgical method of treating areas of the brain).
- Dementia of various etiologies.
- Endogenous depression.
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Release form
Ceregin is produced exclusively as a solution for injection and infusion. Transparent liquid with a yellowish tinge in ampoules of white glass with a volume of 1 ml No. 10 or 5 ml No. 5 in contoured cellular pallets made of polyvinyl chloride (PVC), packed in original factory carton packs.
Pharmacodynamics
Whey protein is an active ingredient in Ceregin. The raw material for obtaining hydrolyzate is the brain of pigs and cattle.
The composition of a multicomponent medicinal preparation includes bioactive compounds, low molecular weight neuropeptides that can overcome the physiological barrier between the circulatory system and the central nervous system, which directly enter the cerebral neurocytes.
Strengthens the protective function of neuronal tissue from the pathological effects of lactic acidemia. Prevents the occurrence of free radicals, the development of neurodegenerative phenomena in the brain tissues.
Intensive trophic activity is realized by inhibiting, sometimes stopping the neuronal degenerative processes in the brain. Has a positive effect in the presence of cognitive disorders, positively affects the processes of memorization, concentration and transfer of information, activates mnestic functions, has a neuromodulatory function.
Pharmacokinetics
The pharmacokinetic effect of the drug is not possible to investigate because of its multicomponent nature.
Dosing and administration
Ceregin is used exclusively in the form of intramuscular injections from 1 to 5 ml and intravenous drip infusions from 10 to 50 ml. Dosage and duration of the treatment cycle depend on the severity and nature of the disease, the dynamics of therapy and the age of the patient.
The usual duration of treatment is 1 month (the minimum number of injections is 5 per week, but it is better daily)
In cerebral lesions, acute cerebral circulatory insufficiency, postoperative period, the drug is injected daily intravenously by a drip adult dosage of 10-50 ml per day. On 100-250 ml of saline for 1-1.5 hours. The treatment cycle is from 10 to 25 days.
In the rehabilitation period after UCLC, adult patients are routinely prescribed from 5 to 10 ml / day. Intravenously for 20 days or 1 month depending on the dynamics.
With dementia of vascular origin for adults, 20-30 ml per 100-200 ml saline. Duration of admission - 20 injections.
Use of the ceregin during pregnancy
Due to the fact that the study of Ceregin during the gestation or lactation period was not carried out, the drug is not prescribed.
Contraindications
- hypersensitivity to drug substances,
- pathology of the genitourinary system,
- period of pregnancy,
- period of lactation,
- convulsive alertness.
Side effects of the ceregin
Aggressiveness, overexcitation, insomnia, confusion.
Nausea, digestive system disorders, diarrhea, vomiting.
Local allergic manifestations (hyperemia, itching, fever).
Possible hypersensitivity reactions - cephalalgia, rash, rapid and difficult breathing, pain in the cervical region, anaphylactic shock.
With the introduction of Ceregin at high speed - heat, vertigo, hand tremor, arrhythmias
It is necessary to apply Ceregin very carefully in patients prone to allergic diathesis. Do not use the drug with solutions capable of altering the level of acidity of Ceregin or containing fats.
Overdose
To date, there has been no information about an overdose of the drug.
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Storage conditions
Stored in the usual way - in a dark room with a temperature of air no more than 20 о С. Do not freeze. Keep away from children.
Shelf life
The date of manufacture and expiry date are shown on the original packaging. With proper storage, it is 36 months.
Attention!
To simplify the perception of information, this instruction for use of the drug "Ceregin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.