Celascon

Celascon is a vitamin preparation for the treatment and prevention of avitaminosis and colds. Consider the main types of medication, indications for its use and other features.

The pharmacological group of Celascon is vitamins, simple preparations of ascorbic acid (vitamin C).

The active substance of the drug is ascorbic acid. This component is indispensable for the normal functioning of the body and the formation of connective tissue. The substance is involved in the formation of collagen and intracellular mass. Ascorbic acid takes part in the hydroxylation of lysine and proline in peptide networks due to the synthesis of collagen. It is involved in many redox reactions that occur in the body. Metabolizes folic acid, tyrosine, which are responsible for the synthesis of proteins, serotonin and carnitine. Increases the absorption of iron and stabilizes the integrity of the capillary walls.

Indications Celascon

Despite the fact that vitamin C is necessary for the normal functioning of the body, there are a number of prescriptions for its use. The main indications for the use of Celascon:

• Treatment and prevention of avitaminosis and hypovitaminosis
• Unbalanced nutrition
• Increased physical and mental loads
• Recovery after severe diseases
• Lactation and pregnancy
• Burn disease
• Feverish condition against the background of SARS and ARI
• Chronic infections
• Alcoholism and nicotine addiction
• Intoxication with iron preparations
• Idiopathic methemoglobinemia

The drug is prescribed in the complex therapy of various diseases to increase the body's resistance. With lesions of the gastrointestinal tract, pulmonary bleeding, poorly healing wounds and other pathologies.

Release form

The drug has several forms of release, which allows you to take Celascon patients of all ages. Celascon is available in the following forms:

• Pills
• Dragee
• Chewable Tablets
• Powder for solution for oral administration
• Drops for oral administration
• Effervescent tablets

Each tablet contains 500 mg of ascorbic acid. The tableted form is produced in polypropylene tubes of 10 and 20 pieces. In each pack three tubes per 10 tablets and one to 20.

Celascon effect

For the treatment of colds and a lack of vitamin C, patients are assigned a Celascon effect. Medication refers to the pharmacological group of simple preparations of ascorbic acid. Form release - capsules prolonged action. The active substance is ascorbic acid, each capsule contains 500 mg. Auxiliary components are: titanium dioxide, gelatin, talc, yellow dye, spherical sugar and others.

• Ascorbic acid refers to the water-soluble vitamins necessary for the normal functioning of the body. The substance is quickly absorbed into the digestive tract and distributed to the tissues. Uniform action of the vitamin keeps for 8-12 hours after oral administration. Since Celascon is released in the form of granules, the active components are released gradually, which does not lead to excessive concentration.
• The medication is prescribed with a deficiency of vitamin C in the body, to improve the protective properties of the immune system in infectious and inflammatory diseases. Celascon is indispensable during pregnancy, lactation, for the elderly and teenagers. Ascorbic acid is used in the complex therapy of respiratory diseases, long-term healing of wounds, fractures and other lesions.
• Celascon effect is not recommended for use with hypersensitivity to ascorbic acid and other components, with thrombophlebitis and thrombosis. With special care, it is prescribed to patients with disorders of iron metabolism, diabetes mellitus, insufficiency of glucose-6-phosphate dehydrogenase and nephrolithiasis in anamnesis.
• The way of application and dosage is individual for each patient. Adults and teenagers are prescribed 1 capsule per day. With gipovitaminoze appoint 2 capsules per day for 7-10 days. Capsules are not recommended to chew, they must be swallowed whole, washed down with a copious amount of liquid.
• In the case of an overdose, changes in renal excretion of the active ingredient and uric acid are observed. Prolonged use of elevated doses provokes hypovitaminosis, allergic reactions, attacks of nausea, vomiting and diarrhea.

Celascon Mandarin

In the period of catarrhal diseases, the strengthening of the immune system should be a priority in people with a weakened body. Celascon mandarin is a vitamin remedy, the active ingredient of which is ascorbic acid. Each capsule of Celascon contains 500 mg of the substance. Auxiliary ingredients: sodium bicarbonate, mandarin flavor, citric acid, sorbitol, lactose, fumaric acid. The medication is released in the form of effervescent tablets to prepare a solution for oral administration.

• I prescribe medication for adults and children over 12 years for treatment and prevention of vitamin C deficiency, vitamin deficiency, hypovitaminosis, asthenic condition. Tablets are contraindicated to use with individual intolerance of the active ingredients, with urolithiasis. With special care appoint to patients with intolerance to fructose, iron metabolism disorders, with severe kidney disease, diabetes, propensity to thrombosis and with increased blood clotting.
• Vitamin C has a stimulating effect, so it is not recommended to take it before going to bed. Dosage is individual for each patient and depends on the indications for use. Typically, appoint 500 mg once a day. The tablet should be dissolved in a glass of water and drunk. The average course of treatment is 10 days.
• Celascon is well tolerated, but in case of an overdose it causes various skin allergic reactions, nausea, vomiting, diarrhea. Symptomatic therapy is indicated to eliminate adverse symptoms.

Celascon red orange

Vitamin preparations are excellent stimulants of the body, they help to maintain health under the influence of various negative factors. Celascon red orange refers to the drugs of ascorbic acid, which are involved in strengthening the immune system. It is released in the form of capsules and powder for the preparation of solution.

• The drug is prescribed to treat deficiency of ascorbic acid in the body, strengthening of the immune system in infectious and inflammatory diseases. Celascon is recommended for alcoholism, tobacco smoking, various chronic diseases and slow healing of wounds. Very often tablets are part of the complex therapy of viral lesions, anemia, liver disease, varicose syndrome and other pathologies.
• The drug is prescribed for adults and children over 3 years. The daily dosage should not exceed 500 mg, higher doses of 1000 mg are used for hypovitaminosis. The duration of therapy is individual for each patient. Before use, the tablet must be dissolved in a glass of water. The main contraindication to use is thrombosis, thrombophlebitis, hypersensitivity to the components of the drug.
• Side effects occur when the recommendations for the use of the drug are not observed. Typically, this is nausea, vomiting, diarrhea, urticaria, hemolytic anemia, kidney failure, increased fatigue. The use of high doses during pregnancy and lactation can cause hypovitaminosis in newborns, so taking vitamin is only necessary for medical purposes.

Pharmacodynamics

The mechanism of action of the drug is based on its composition. Pharmacodynamics of the main active component - ascorbic acid (vitamin C), affects the functioning of the whole organism. This vitamin is not formed in the human body and comes only with food or medicines. The daily requirement for this substance is 90 mg. This dose eliminates avitaminosis and signs of hypovitaminosis.

The active component is responsible for the transfer of electrons to the enzymes and their supply of reducing equivalents. The drug takes part in the hydroxylation of proline and lysine residues, hydroxylizine, oxidation of folic acid. The agent increases the activity of amidating enzymes, which are responsible for the processing of cholecystokinin and oxytocin. It restores and promotes absorption of Fe3 + to Fe2 + in the intestine, participates in steroidogenesis in the adrenal glands. The main task of ascorbic acid is the synthesis of proteoglycans, endothelium of capillaries, collagen. The drug improves the secretion of iron by improving the acid-forming function of deferoxamine.

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Pharmacokinetics

After ingestion, ascorbic acid is quickly and completely absorbed from the digestive tract and distributed to the tissues of the body. Pharmacokinetics indicates the maximum concentration of the drug in the intestinal walls, adrenals and pituitary. Most of the vitamin has reversible oxidation in dehydroascorbic acid, whose biological activity corresponds to vitamin C.

The active substance is biotransformed in the liver. The main metabolites are oxalic and 2-sulphuryl acric acid, which are excreted in the urine. The renal threshold of ascorbic acid is 1.4 mg / 100 ml. Drug withdrawal is a sign of saturation with vitamin C.

Dosing and administration

In the presence of indications for the use of Celascon, the doctor selects an individual dosage for each patient. Tablets, powders and effervescent tablets for the preparation of solutions must be taken orally after eating.

Method of administration and dose Celascon

Prevention of hypovitaminosis:

• Adults - 50-100 mg
• Children 3-5 years - 25 mg
• Children 6-14 years - 50 mg
• Adolescents 14-18 years - 75 mg
• At pregnancy and a lactemia - 300 mg within 10-12 days with the further reduction of a dose up to 100 mg / day

With a therapeutic purpose take 50-1000 mg of Celascon, depending on the medical recommendations. With chronic intoxication with iron preparations, adults are prescribed 200 mg each, children under 10 years old have 50 mg each, and for children over 10 years 100 mg per day. To eliminate idiopathic methemoglobinemia, take at least 150 mg per day. Powder for the preparation of solutions is diluted in a proportion of 1000 mg per 1 liter of water.

Use Celascon during pregnancy

The use of vitamin preparations during the period of gestation is recommended for all women. This ensures the normal functioning of the maternal organism, which has a positive effect on the growth and development of the fetus. The use of Celascon during pregnancy is possible only for medical purposes. This is due to the fact that the independent use of higher dosages is dangerous for the mother and child. The doctor calculates the necessary dose, focusing on the period of pregnancy. So, the minimum daily requirement for vitamin C in the II and III trimesters is 50-60 mg.

After applying the vitamin, the active substance, i.e. Ascorbic acid, penetrates the placental barrier. Therefore, it must be taken into account that the fetus adapts to high doses of the drug, which can lead to the development of a withdrawal reaction and ascorbic disease. In the period of lactation, the daily need for vitamin 80 mg. The active ingredient is excreted in breast milk. The minimal use of the medicine by the mother is an excellent prevention of vitamin C deficiency in the child. 

Contraindications

Ascorbic acid, like a number of other drugs, has contraindications for use. Vitamin is forbidden to use when:

• Individual intolerance to vitamin C
• Diabetes
• Deficiency of glucose-6-phosphate dehydrogenase
• Nephrolithiasis
• Thalassemia
• Hyperoxaluria
• Hemochromatosis

The medicine is not taken in doses exceeding therapeutic, as it threatens with various allergic reactions and pathologies on the part of many organs and systems.

Side effects Celascon

Long-term use of drugs of ascorbic acid leads to a number of side effects. Celascon can cause such adverse events:

• CNS - headaches, fatigue, sleep disturbances.
• Gastrointestinal tract - irritation of the mucous membrane of the digestive tract, stomach cramps, nausea, diarrhea, vomiting.
• Cardiovascular system - thrombosis, decreased capillary permeability, increased blood pressure, myocardial dystrophy.
• Allergic reactions - itching, rashes, redness, anaphylactic shock.
• The endocrine system is glucosuria, hyperglycemia.
• The urinary system is damage to the glomerular apparatus of the kidneys, hyperoxaluria.

In addition to the above symptoms, there is a change in laboratory indicators: thrombocytosis, erythropenia, leukocytosis. Possible metabolic disorders, puffiness, a feeling of heat.

Overdose

The use of high doses of Celascon causes overdose symptoms. Ascorbic acid is well tolerated, its excess is excreted by the kidneys with urine. But prolonged use of the drug causes oppression of the function of the insular apparatus of the pancreas. Overdose can cause a violation of renal excretion of ascorbic and uric acids.

Most often, overdose symptoms are accompanied by vomiting, nausea, diarrhea and allergic reactions. Negative manifestations disappear after the drug is withdrawn. With pronounced side effects it is recommended to carry out symptomatic therapy.

Interactions with other drugs

Strengthening the immune system is a lengthy process that requires the use of several drugs at the same time. The interaction of Celascon with other drugs is possible with the complex therapy of acute respiratory viral infections, ARI, beriberi, heavily healing wounds, infections and inflammations. In order for the drug interaction to not cause side effects, all drugs should be selected by a doctor.

• Ascorbic acid increases the concentration of tetracyclines and benzylpenicillin.
• Improves absorption of iron preparations and increases its excretion when used with deferoxamine.
• Vitamin C reduces the effect of indirect anticoagulants and heparin.
• Increases the clearance of ethanol, which reduces the concentration of the active substance of Celascon in the body. Long-term use and high dosage violate the interaction of ethanol and disulfiram.
• Reduces the effectiveness of neuroleptics and tricyclic antidepressants, increases the excretion of mexiletine.
   

Storage conditions

The medicine should be kept in a place protected from sunlight and inaccessible to children. Compliance with storage conditions is a guarantee of preserving the pharmacological properties of the medicament during its shelf life. All forms of release of the medicinal product must be stored at a temperature of at least 30 ° C.

Shelf life

Celascon is allowed to be used within 24 months from the production date. This expiration date extends to all forms of release of Celascon. At the expiration of the medicine is prohibited to use and must be disposed of. The use of an overdue medication can lead to uncontrolled side effects on the part of many organs and systems.