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Health

Cebrilizine

, medical expert
Last reviewed: 03.07.2025
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The nootropic drug Cebrilysin is similar in pharmacological properties and composition to Cerebrolysin.

Indications Cebrilizine

Indications for the use of Cebrilysin are:

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Release form

Cebrilysin is a liquid for intramuscular injections. 1 ml ampoule, in a plastic cell package, 1 or 2 packages per cardboard box. Available in quantities of 5 or 10 ampoules per box.

The active substance of the drug is represented by hydrolysate of animal brain, which has amino acid and peptide composition. The auxiliary preservative is phenol.

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Pharmacodynamics

Cebrilysin is a nootropic of peptide origin that exhibits neurotrophic activity that resembles the effects of natural factors in the development of neurons.

The preparation contains a concentrated substance from the brain structures of large cattle, which is represented by a complex of left-handed amino acids and low-molecular bioactive neuropeptides in a state of natural balance.

Due to their low molecular weight, peptides easily penetrate the encephalitic barrier and go directly to the neurons of the brain.

The active substance of Cebrilysin is capable of increasing aerobic energy metabolism, improving intracellular protein production in both the growing and aging brain. In addition, the drug prevents the formation of independent radical particles, reduces the amount of residual product from fat oxidation processes, increases the percentage of survival of nerve cells in conditions of oxygen and nutrient deficiency, neutralizes damage to neurons by amino acids and lactate, and activates the creation of synapses.

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Pharmacokinetics

The drug has a fairly complex chemical and biological composition. Its active component consists of a balanced and stable complex of bioactive low-molecular regulatory oligopeptides, which are capable of providing a combined multifunctional effect. Based on this, it is not possible to analyze the pharmacokinetic properties of each component of Cebrilysin.

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Dosing and administration

The drug is intended for intramuscular administration. At the discretion of the doctor, injections are administered once every 24 or 48 hours, from 1 to 5 ml.

The duration of the therapeutic course is about 1 month, with the possibility of repeating the course after 3-6 months.

As a rule, the dosage and duration of therapy depend on the course and complexity of the pathology. The patient's age is also important.

To achieve the best result, it is recommended to prescribe repeated treatment courses until a stable positive result from the treatment is established. After completing one therapeutic course, the frequency of administration of the drug in the subsequent course can be reduced to 1 injection every 48-72 hours.

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Use Cebrilizine during pregnancy

The use of Cebrilysin during pregnancy and breastfeeding is possible only when the expected beneficial effect for the expectant (or nursing) mother is much higher than the possible danger to the future (or breastfeeding) child.

The few experimental data available do not indicate any teratogenic or toxic effects of the active ingredients of the preparation on the embryo. However, it should be remembered that no special clinical trials have been conducted on this issue.

Taking into account the above, we can draw the following conclusions:

  • if possible, it is better to avoid using Cebrilysin during pregnancy and lactation;
  • if taking the drug is unavoidable, then it is prescribed very carefully, and only in the second half of pregnancy;
  • When taking the drug during breastfeeding, it is recommended to stop breastfeeding.

Contraindications

Contraindications to the use of Cebrilysin may be the following:

  • tendency to allergies to some components of the drug;
  • renal failure;
  • tendency to seizures, epilepsy;
  • pregnancy, first half.

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Side effects Cebrilizine

If the drug is injected carelessly or too quickly, a feeling of heat, increased sweating, and dizziness may occur. Sometimes, rapid or irregular heartbeat may be observed.

Patients who are hypersensitive to certain medications may develop an allergic reaction that results in skin redness, rash, fever and collapse.

A burning sensation and redness may occur at the injection site.

Sometimes it is possible to develop dyspeptic disorders: attacks of nausea, diarrhea or constipation.

Less often, the drug can cause sleep disturbances, irritability, and convulsive contractions of the muscles of the limbs.

Overdose

There have been no cases of overdose with the drug Cebrilysin. It is possible to assume that side effects will increase in case of overdose. Treatment - stop taking the drug, carry out measures to detoxify the body.

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Interactions with other drugs

Increased activity of each other is possible with the combined use of Cebrilysin with antidepressants and agents that inhibit monoamine oxidase (Selegiline, Eldepryl, Yumex, etc.). If combined use cannot be avoided, it is recommended to reduce the dosage of the antidepressant.

Cebrilysin cannot be combined in one administration with lipid solutions, as well as with substances capable of changing the pH of the environment (from 5.0 to 8.0).

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Storage conditions

The drug is stored in a dark place. The optimal temperature for preserving the drug is +18-20°C.

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Shelf life

Shelf life: up to 3 years.

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Attention!

To simplify the perception of information, this instruction for use of the drug "Cebrilizine" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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