The drug is intended for intracavernous administration. To do this, use a size needle of size 27-30. The way of application and dose should be selected by the doctor individually.
Intracavernous administration should be performed under sterile conditions. Localization of the injection is a site on the dorsolateral surface of the upper third of the penis (closer to the testicles). To avoid the development of local adverse reactions, you need to change the injection site each time, handle it with a swab with alcohol and avoid getting the needle into the visible veins.
For the preparation of the drug before administration, it is necessary to remove the plastic cap from the vial and wipe the rubber cap with an alcohol swab. Then you need to inject 1 ml of the solution from the syringe with the needle into the powder dilution bottle. To accelerate the process of dissolution, you can several times wipe the bottle.
Now you need to get the drug into the syringe (a little more than the intended dose), change the needle and remove the air from the syringe (this will result in a little drug).
After processing the place of administration of the drug, you need to make an injection. The remaining volume of the drug should not be used anymore, since the drug is not stored in a dissolved state.
With the diagnostic purpose, Kaverdzhekt is used in a dose of 20 mcg (for men without neurological pathology) and not more than 10 mkg (with neurological pathology), after which it is necessary to spread the massage movements along the penis. The therapeutic effect is assessed by establishing the time of the onset of erection and its duration. If the erection persists for more than an hour, it is necessary to take measures to accelerate the excretion of the drug. To avoid the development of priapism by the time the patient leaves the clinic, he should be rid of the erection and completely relax member.
The method of administration and dose are established, based on the severity of the pathology, the age of the patient and the presence of concomitant diseases. The initial dose for men with a lesion of the spinal cord is 1.25 μg, the subsequent two times more. The fourth dose should be 10 μg and then increase by 5 μg until an effective dose is obtained for the desired effect.
In the case of vascular, mixed or psychogenic reasons for the development of erectile dysfunction, it is recommended to start with 2.5 μg, then increase by 5 μg until the necessary therapeutic effect is obtained.
When the result is achieved, the dose should not be used more often than 1 time per day and more often 3 times a week. At the beginning of the treatment, intracavernosal injections with the drug should be performed by a medical professional, after which, having mastered the principles of administration, the patient can independently perform manipulation at home.
The optimal dose is the amount of medicine used, which provides an erection during the first hour. Do not exceed the maximum dosage (60 mcg) to prolong the erection for more than an hour. In most cases, 5-20 μg of alprostadol is sufficient.