Tablets from varicose veins

Tablets for the treatment of varicose veins can be divided into 2 categories: medicines (LS), which dilute blood, that is, inhibiting platelet aggregation and blood rheology improving (anticoagulants), as well as drugs that help strengthen the walls of blood vessels. It should be noted that in therapy it is most effective to use both types of drugs - an integrated approach will be more effective. Tablets from varicose veins are considered the most popular way of drug treatment of this disease.

Indications of the tablets from varicose veins

Among the indications for the use of tablets are venous insufficiency in chronic form, trophic ulcers and other trophic disorders observed in varicose veins. In addition, these drugs help with chronic thrombophlebitis, and are also used as an auxiliary therapy after surgical removal of varicose veins or sclerotherapy.

[1], [2]

Release form

The existing tablets of varicose veins can be divided into several groups:

• Phlebotonics, which include Detralex, as well as Flebodia and Venarus;
• Anticoagulants - such as aspirin and Cardiomagnet;
• Drugs that prevent the development of edema: Venosmin;
• Antiaggregants - in this category are Kurantil and acetylsalicylic acid;
• Preparations that remove skin hyperpigmentation: Ginkor fort or Actovegin;
• Antioxidants, which include Ascorutin;
• Fibrinolytics, which include Heparin.

Detralex

Detralex quite effectively eliminates varicose veins - the drug has venotonic properties, and besides it contributes to the stable operation of venous valves in unidirectional blood flow and improvement of lymph flow function. The drug also helps to reduce the permeability of capillaries and eliminate inflammation. In the case of systematic use of tablets, the degree of varicose veins on the legs decreases. Taking the medicine allows you to remove the clinical signs of venous insufficiency - pain in the lower extremities, swelling and sensation of severity and sensitivity disorders.

[3], [4]

Flebodia

Phlebodia 600 tablets help to reduce the degree of vascular permeability, increase the tone of the capillary walls, while not allowing them to expand, and normalize the blood flow. The active substance of the drug is diosmin. The drug also has anti-inflammatory properties.

[5]

Venus

Venus on the basis of diosmin and hesperidin is very effective in the early stages of development of varicose veins. This drug has virtually no contraindications, so it is classified as safe. With the expansion of veins, phlebologists are advised to carry out treatment with seasonal courses of the drug. Venarus is prescribed in case of problems with blood circulation in the vessels. It has a beneficial effect on the dilated veins, removes the vascular sprouts and slows the development of thrombophlebitis.

Troxevasin

The Troxevasin contains an active component of troxerutin, which helps stabilize the walls of blood vessels.

The drug perfectly copes with the inflammatory process, reduces the permeability of capillaries, and also has a venotonic effect and removes puffiness. It is usually prescribed for venous insufficiency in a chronic form, as it allows you to eliminate convulsions and pain, reduce edema and the severity of varicose ulcers and trophic disorders.

The properties of tablets from varicose veins are examined using the example of the preparation Flebodia.

Pharmacodynamics

Tablets exert a phlebotenic effect (obfuscate the dilatability of the veins and increase their tone (depending on the dosage), and also reduce stagnation in the veins). In addition, they increase the frequency of contraction and tonus of lymphocapillary vessels, lowering lymphatic pressure and strengthening their functional density. Also, the drug enhances the stability of capillaries (depends on the dosage), reducing the permeability of their walls. Together with this, it lowers the adhesion of leukocytes to the vein wall, as well as their movement into paravenous spaces. Flebodia improves perfusion in skin tissues and diffusion of oxygen, and also has anti-inflammatory properties. Promotes an increase in the vasoconstrictor effect of norepinephrine and epinephrine, prevents the production of free radicals, and in addition to the compound of thromboxane and PG.

[6], [7]

Pharmacokinetics

The drug is quickly absorbed from the digestive tract, 2 hours after taking the pill falls into the plasma. The maximum index of saturation in the blood plasma reaches 5 hours after ingestion. It is evenly concentrated and distributed in the layers of the hollow venous walls, as well as the subcutaneous veins on the legs; in a smaller amount remains in the lungs, as well as kidneys with liver and other tissues. The selective accumulation of the diosmin substance and / or the products of its disintegration in the vein vessels reaches a maximum value 9 hours after the use of the tablet and continues to persist for 96 hours. Flebodea is excreted through the kidneys (79%) and intestine (11%) and bile (2.4%).

[8], [9], [10], [11]

Dosing and administration

Ascorutin tablets are usually drunk three times a day. 2 capsules after eating. Dosage can also be prescribed by a doctor individually. The course is 2 weeks, after which you need to take a break for a similar period, and then resume the reception of drugs.

Detralex is prescribed in a dosage of 2 tablets / day. First you need to take them in the morning and in the evening with food. After 7 days of such reception the transition to the use of 2 tabs is allowed. At a time.

Flebodia 600 at an early stage and in case of absence of various complications it is necessary to drink 1 table. 1 rub. / Day. For 2 months. If the disease is of moderate severity, the medication takes 3 months. If venous expansion is observed trophic ulcers and nodes, the treatment course lasts at least six months.

Actovegin should drink 2 tablets. Three times a day. Before eating, wash down with water.

Tablets Troxevasin should be eaten with food. On average, 600 mg of the drug are allowed per day (2 tablets). If there is such a need, the dosage is increased. With maintenance treatment take 1 table / day. For 3-4 weeks.

[20], [21], [22], [23]

Use of the tablets from varicose veins during pregnancy

Some pills from varicose can be taken with pregnancy with certain restrictions. For example, Troxevasin on the 2nd and 3rd trimesters is allowed to use only in cases where the benefit to the mother is higher than the possible risk to the baby. And Detralex can be used only on the 3rd trimester.

Contraindications

Among the contraindications to the use of drugs from varicose: pregnancy at the 1st trimester, lactation period, ulcer of the duodenal ulcer or stomach, exacerbated chronic gastritis. With increased sensitivity to the elements of the drug - for example, Troxevasin should not be taken if the patient has intolerance to rutozides, and Detralex with sensitivity to diosmosis. Also it is forbidden to use to children under 18 years old. Long-term use may be prohibited in the case of kidney failure.

[12], [13], [14]

Side effects of the tablets from varicose veins

Among the adverse reactions: skin allergies - dermatitis or eczema, as well as urticaria. Neurovegetative disorders and dyspepsia may occur - nausea, heartburn, pain in the abdomen (usually pass on their own). In addition, there is a headache, sometimes pain in the chest, a sore throat. There may be hyperemia, allergic dermatitis, edema of the eyelids, lips or face entirely; very rarely observed edema Quincke.

[15], [16], [17], [18], [19]

Interactions with other drugs

When interacting with ascorbic acid, the properties of Troxevasin are enhanced.

[24], [25], [26], [27], [28]

Storage conditions

Tablets from varicose should be stored in a dry place, closed from light with an air temperature of 15-25 ° C.

[29], [30], [31]

Shelf life

The shelf life of tablets is generally 2-5 years from the date of manufacture.

[32], [33], [34]

Effective tablets against varicose veins

In the treatment of varicose veins, tablets are not the main medical tool, but it is obvious that they have a certain effect - being an integral part of the overall complex therapy.

Nowadays many different venotonic drugs are sold, but most of them have similar components and medicinal properties. Therefore, their effectiveness largely depends on how the active substance is absorbed by the body and what its concentration in the blood. With varicose veins, venotonics, which strengthen the walls of the vessels, and preparations that dilute the blood and interfere with the formation of thrombi, are effective.

[35], [36]

Tablets for the prevention of varicose veins

Tablets from Venarus varicose are very popular and effective. They are often used as a preventive agent. The main active ingredients of the drug are bioflavonoids. Among the functions of the drug:

• the tone of the walls of veins increases;
• the strength of manifestations of the disease is weakened;
• a qualitative curative effect on the early or acute stage of the disease;
• reduces the possibility of complications.

Take the pill should be combined with external drugs - ointments, creams or gels from varicose veins.