Tylolfen

In the autumn-winter period, a cold and flu are waiting for a person at every corner. It will be almost impossible to cope with this problem, in this case we mean the probability of avoiding the disease. However, it can be eliminated with the help of special preparations, in particular Tylolfen.

Indications Tylolfen

The remedy is used individually by the attending physician. The main indication for Tylolfen is the symptomatic treatment of influenza. The agent allows you to get rid of a pestering disease in a short time and to relieve the condition of a person from the first minutes of taking the drug.

The medicine is also used for colds. Its action is directed to the destruction of the main virus that is in the body and the restoration of protective functions. Tylolfen is suitable for both children and adults. As for children, it is recommended to take Tylolfen from the age of twelve.

The medication allows to eliminate diseases accompanied by severe fever, severe headache and rhinitis. Literally in a couple of receptions a person will feel much better. The composition of the drug allows you to take it absolutely everything, but there are still some contraindications. This issue will be discussed below. 

Release form

The preparation is in the form of a powder for dissolution. It is accepted exclusively inward. One packet contains 20 mg of powder. The package contains 6 or 12 bags. The drug has no other form of release. In the package, in addition to packages with medicine, there is an instruction. If it is absent, a person has the right to demand it from a pharmacist.

In 20 grams of powder contain both active and auxiliary components. The main substances include: paracetamol in a dosage of 500 mg, chlorpheniramine maleate 4 mg and phenylephrine hydrochloride 10 mg. As auxiliary components are: sodium benzoate, tartaric acid, sodium carbonate anhydrous. Supplement the picture: sugar, quinoline yellow, lemon flavor, citric anhydrous acid, PvP K30, refined sugar. All these components together allow the facility to easily combat the main symptoms of the common cold and flu. 

Tylolfen hot

This is another type of drug. Tylolfen is produced in the form of a powder, which must be dissolved in a glass of hot water. The composition of the drug includes: paracetamol, chlorpheniramine maleate and phenylephrine. As auxiliary components are: refined sugar, lemon flavor, citric anhydrous acid and РVР К30. Together, these substances can lift a person to his feet in a short time.

The medication dose is prescribed by the attending physician depending on the severity of the symptoms. Usually, a day use no more than 4 packets. Take them every 6 hours. Literally after a couple of uses a person will feel relief. Tylolfen can be taken by both adults and children. However, children's age should not be less than 12 years.

This is a very powerful and effective drug. It is enough 3 days of treatment for complete elimination of negative catarrhal symptoms. If there is no effect, you should consult your doctor. 

Pharmacodynamics

It has a pronounced analgesic and antipyretic effect. It is an excellent antihistamine drug, capable of removing any swelling. This effect is achieved due to the content of paracetamol. Additional effect: chlorpheniramine maleate and phenylephrine hydrochloride. The basis of pharmacodynamics is the active components.

Paracetamol. This substance is able to exert an analgesic effect and reduce body temperature. It has an analgesic effect due to an increase in the pain threshold. Antipyretic effect is achieved by affecting the center of thermoregulation, located in the hypothalamus.

Chlorpheniramine maleate. This component belongs to the number of antagonists of histamine H1 receptors. It allows to remove plugging of the nasal canal and hypersensitivity from the eyes.

Phenylephrine. It is a postsynaptic α-receptor agonist. Its action is aimed at stimulating the central nervous system. It has a direct effect and has a vasoconstrictive effect. Actively fights with swelling of the nasal mucosa and its sinuses. 

Pharmacokinetics

When taken orally, paracetamol is well absorbed in the gastrointestinal tract. Its maximum concentration in blood plasma is reached after 10-60 minutes after administration. Thanks to this, relief comes almost immediately. This is not the only property of pharmacokinetics. Paracetamol is able to distribute evenly in most body tissues. Half-life does not exceed 3 hours. Metabolism occurs in the liver. Almost 85% of the dose received is withdrawn in an associated form within a day.

Chlorpheniramine maleate. Absorption is slow, occurs through the gastrointestinal tract. The maximum concentration of the drug in the body is reached after 6 hours after administration. Most of the substance is absorbed with plasma proteins. The half-life period ranges from 2-43 hours. Most of the substance is metabolized. Tylolfen in unchanged form and together with metabolites is excreted together with urine.

Phenylephrine. Absorption passes through the gastrointestinal tract. When taken orally, the component has a vasoconstrictive effect.

It lasts for 4-6 hours. The component is unchanged and, together with metabolites, is excreted in the urine. 

Dosing and administration

It is advisable to consult a doctor before using the medication. This will allow you to choose an individual dosage depending on the severity of the symptoms. The method of administration and dose of Tylolfen has a standard application schedule. However, it does not fit all.

Adults and children should use one packet of the drug every 6 hours, but not more often. Due to the powerful active components, it is often not necessary to use it. The contents of the sachet dissolve in a glass of hot water. If you drink Tylolfen in its pure form is difficult, you can add a little sugar or honey.

To avoid hepatotoxic risk in case of alcohol use, the dose of paracetamol should not exceed 2 grams per day. Duration of treatment is 3 days. If the therapeutic effect is absent and the body temperature remains high, it is necessary to change the treatment regimen. 

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Use Tylolfen during pregnancy

It is not recommended to use the product during the period of bearing of the child. The fact is that in its composition there are powerful active components that can harm the developing organism. Use Tylolfen during pregnancy is possible only on the advice of a doctor and with his permission. In this case, the dosage is adjusted individually.

The first trimester of pregnancy should be in complete rest and not be overloaded with medicines. This period is the most dangerous. During it, the risk of improper development of the baby and even spontaneous miscarriage is preserved. Therefore, the intake of any medication must be clearly agreed with the attending physician. This will avoid possible pathologies in the baby.

When using one or another medication, it is necessary to compare the positive effect for the mother with the risks for the baby. During pregnancy, the life of the child is in the hands of the future mother. Therefore, you need to monitor all actions, in particular, self-administration of medications. 

Contraindications

Any remedy has its own contraindications, Tylolfen is no exception. Use it is not recommended in the presence of hypersensitivity to one of the components of the drug. Uncontrolled reception can lead to the development of an allergic reaction. Another contraindication to use is a pronounced impairment of the functionality of the liver. Receiving a remedy can deal a heavy blow to this organ.

Use the medication is not necessary for acute myocardial infarction. Among the contraindications include the presence of arterial hypertension, as well as complicated retinal angiopathy. Tylolfen should not be taken with severe atherosclerosis of the aorta and cerebral vessels.

On this list of contraindications does not end. Refuse the medication is necessary in the presence of diabetes, bronchial asthma and glaucoma. Finally, children under 12 years of age are treated with Tylolphene. 

Side effects Tylolfen

The agent due to its features can lead to the development of negative reactions from the body. Side effects from Tylolfen can affect the skin. There is a marked rash, redness and even exudative erythema. In some cases, there is Stevens-Johnson syndrome.

The immune system can respond with anaphylactic shock and bronchospasm. From the nervous system may develop headaches, psychomotor agitation, sleep disturbances, heaviness in the limbs and tinnitus.

The likelihood of impaired vision and increased intraocular pressure is not excluded. The digestive system can react with disorders of the gastrointestinal tract. In particular, nausea, vomiting and dry mouth are manifested.

The appearance of renal colic and papillary necrosis is not excluded from the urinary system. Urination is impaired. From the side of the cardiovascular system, tachycardia, dyspnea and pain in the heart are not excluded. Other adverse reactions include: weakness and increased sweating. 

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Overdose

Data on the occurrence of negative reactions from the body have not been reported. Despite this, an overdose is not excluded. It is connected with uncontrolled reception of a medicine. The toxic effect is on paracetamol. Overdose is characterized by the appearance of the following symptoms: nausea, vomiting and pain in the epigastric region. They will appear after 1-2 days after taking the drug. Paracetamol can cause a marked effect on liver cells and kidney capillaries. The possibility of developing necrosis is not ruled out.

In case of an overdose with another active ingredient, namely phenylephrine, several other symptoms appear. A person is very excited (this sign is expressed in children), convulsions, headache and behavior change appear. In this case, it is necessary to immediately wash the stomach. Antidote paracetamol and phenylephrine does not exist.

After washing the stomach, you need to monitor the patient's condition and, if necessary, carry out symptomatic treatment. It is necessary to take sorbents and monitor the work of the respiratory system and circulation. 

Interactions with other drugs

You can not combine this medication with sleeping pills. This can lead to inhibition of the central nervous system. A similar effect occurs when interacting with other drugs, in particular analgesics and MAO inhibitors.

The simultaneous use of antihistamines and Tylolfen may result in an atropine-like effect. A similar action occurs during the administration of antidepressants, antiparkinsonic agents and spasmolytic drugs. This can lead to dry mouth, urinary retention and constipation.

The use of Tylolphene together with furazolidone leads to an increase in adverse reactions. This can occur with the simultaneous use of the drug along with thyroid hormones and sympathomimetics.

With simultaneous use with nitrates, it is possible that their therapeutic effect is weakened. Barbiturates can reduce the antipyretic effect of Tylolfen. 

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Storage conditions

In order for the drug to serve for a long time, it must be stored correctly. Optimal storage conditions include the fulfillment of three main criteria. The first thing to do is to observe the temperature regime. Its rate should not exceed 25 degrees. Tylolfen can not be stored in the refrigerator. The second rule says: the medicine should always be in a dry and dark place. This will preserve its pharmacological properties for a given time. Finally, the third rule: the remedy should be away from children. If you comply with all the prescribed criteria, the drug will last for several years.

After opening the package and diluting the powder, it should be used immediately. It is not recommended to prepare a preparation in advance. In this case, it will lose all its basic properties and will not have the proper effect. Storage conditions play an important role in the "existence" of all medicines, in particular Tylolfen. 

Shelf life

Under all storage conditions, Tylolfen will last for 3 years. When the expiration date expires, it is not recommended to use the product. How will behave Tylolfen and how will affect the human body - it is not known. Possible the development of serious allergic reactions and poisoning. It is also possible that the remedy will not have any effect.

During the entire shelf life, special storage conditions must be observed. Pay attention to the appearance of the powder. It should not change color, smell and taste. Otherwise, this indicates that the storage is not correct. The product can not be kept in a wet place. It comes in the form of a powder in a bag. Under damp conditions, Tylolfen is able to get wet. This will lead to useless means.

Do not allow children to enter the storage area. They can harm themselves and the medicine. Proper storage is the guarantee of a long service life of any product.