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Okazin
Last reviewed: 23.04.2024
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Ocacin (Ocacin) is an antimicrobial ophthalmic agent of a group of first-generation fluoroquinolone antibiotics. ATX code S01AE04, J01MA07. The international name is Lomefloxacin; Other trade names: Lomecin, Lomeflox, Lofoks and others.
Indications Okazin
Okaccine eye drops are used in the treatment of such ophthalmic diseases as acute and chronic bacterial inflammation of the eye mucosa (conjunctivitis), inflammation of the eyelids (blepharitis), inflammation of the cornea (keratitis), inflammation of the lacrimal sac (dacryocystitis) and other eye infections.
Release form
Eye drops 0.3% in vials of 5 ml.
Pharmacodynamics
Okatsin shows bactericidal activity against many gram-negative and some Gram-positive aerobic microorganisms (Staphylococcus saprophyticus, Staphylococcus aureus and Staphylococcus epidermidis), as well as Chlamydia trachomatis. With regard to Streptococcus spp., Streptococcus pneumoniae, Pseudomonas cepacia, Ureaplasma urealyticum, Mycoplasma hominis and anaerobic bacteria, the drug is ineffective.
The active substance Okatsina - Lomefloxacin hydrochloride - blocks the action of bacterial enzymes (topoisomerases II and IV), which stops the process of transcription and replication of their DNA, protein synthesis and other biochemical processes that ensure the viability of bacterial cells.
Pharmacokinetics
Data on the absorption of eye drops Okacin after intraconjunctival administration are not given.
Dosing and administration
Eye drops Okacin should be instilled in the lower conjunctival sac: at the initial stage of treatment - one drop every 5 minutes for 25 minutes or one drop per hour for 8 hours. In the following days it is necessary to instill one drop in each eye 2-3 times a day. The duration of the course of treatment is 7-9 days.
[2]
Use Okazin during pregnancy
Contraindicated
Contraindications
Contraindications to the use of the drug are hypersensitivity to fluoroquinolones, soft contact lenses, children's age (up to 15 years).
Side effects Okazin
Side effects of Okatina are manifested in the form of a fast, minor burning sensation in the eyes after instillation. Also, after topical application, allergic reactions to ultraviolet radiation (dyspnea, urticaria, erythema, pruritus of the skin), which are often caused by systemic application of the tablet form of lomefloxacin, are not excluded. Therefore, during the use of this drug is better to hide from direct sunlight.
[1]
Overdose
Storage conditions
Store in a darkened and inaccessible place for children (list B), at room temperature.
Shelf life
The drug in an unopened vial is 3 years.
Attention!
To simplify the perception of information, this instruction for use of the drug "Okazin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.