Famvir

Famvir is a medical product that has been developed to combat various viruses. When developing, pharmacists have achieved that the viruses are destroyed directly from the cellular level. Using the main active substance-penciclovir - helps to achieve very rare cases of repeated infection with viruses. Famvir not only reduces the symptoms that are pronounced, but also minimizes the consequences after the illness, for example - postherpetic neuralgia.

[1], [2], [3], [4]

Indications Famvir

The medication is prescribed for the following diseases:

• Infectious diseases that were caused by herpes zoster. This group also includes postherpetic neuralgia and ophthalmoherpes.
• Infectious diseases that were caused by the first and second type of herpes, the primary infection, the suppression of re-infection.
• Infectious diseases that were caused by herpes viruses in patients with reduced immunity.

[5], [6]

Famvir with herpes

Penciclovir is an active substance that fights viruses at the cellular level. Therefore, if you have any symptoms of herpes in the body - you need to start using the drug.

The medication taken with herpes penetrates into those cells of the body that were infected with the virus. The drug is in infected cells for more than twelve hours and actively affects the very essence of the disease - viral replication of desicoribonucleic acid is destroyed. 

[7],

Famvir for children

Children are patients with unstable and weak immunity. Therefore, in the case of a viral disease of the child, it is possible to start taking the medication.

But be extremely careful before you start taking medicine for children. Since at the moment there are not enough published studies that prove a 100% guarantee of safe and effective treatment for the child.

[8], [9]

Release form

The medication has various forms of release. They depend on how many milligrams of the working substance is in one tablet.

• Pills that are covered with a white sheath. They are round, biconvex, have cut edges. On one side is written the engraving "FV", on the reverse side the dosage is 125 milligrams.
• Pills that are covered with a white sheath. They are round, biconvex, have cut edges. On one side is written the engraving "FV", on the reverse side the dosage is 250 milligrams.
• Pills that are covered with a white sheath. They are oval in shape, biconvex, have cut edges. On one side is written the engraving "FV500" - the dosage of the medication is indicated.

[10], [11]

Pharmacodynamics

The medicine has the main active substance penciclovir. Famvir is soon transformed into penciclovir, which in turn demonstrates a negative activity with respect to herpesviruses of the first and second type, the virus of chicken pox, the virus Epstein-Barr and cytomegalovirus.
The antiviral effect in the pharmacodynamics of Famvir as a result of the transformation into penciclovir was manifested on different models of herpes in animals. In cells that have been infected with the virus, penciclovir is converted into monophosphate over a short period of time.

In those cells that were not susceptible to the herpes virus, the effect of penciclovir concentration of penciclovir triphosphate is very small - its index tends to zero. Accordingly, the pharmacodynamics of the drug can not adversely affect the healthy cells of the body and interacts only with infected locations.   

[12], [13]

Pharmacokinetics

Pharmacokinetics provides three stages of its activity after ingestion.

Absorption into the blood occurs within a few hours, after administration. Bioavailability Famvir reaches seventy seven percent.

Distribution in the body occurs on the infected cells simultaneously, regardless of the frequency of admission. With blood plasma, less than twenty percent of the drug binds.

The pharmacokinetics of the drug involves the withdrawal of the drug two hours after ingestion. Metabolites go through the urine. 

[14], [15]

Dosing and administration

The drug is taken orally, one tablet. Each pill should be washed with plenty of water. Treatment should begin with the first symptoms, which may indicate the presence of viral pathogens.

Depending on the disease itself and the degree of its course, the dose is calculated as follows:

• In the acute phase, 250 milligrams three times a day or 500 milligrams twice a day. In some cases, 750 milligrams can be taken once a day. Continue the course is necessary for seven days. 
• Those who have been infected with the virus and have reduced immunity should take 500 milligrams three times a day. The course lasts ten days.
• Herpes virus and infection, its provoking - 250 milligrams of the drug three times during the day. It takes five days to continue treatment. But it is important to consider that the medication should be taken after the first manifestations of unpleasant symptoms.
• In the case of a recurrence of symptoms - the instructions for use provide 125 milligrams of medication twice a day. Treatment continues for five days. Treatment should be started after the appearance of the first symptoms of the disease.
• Those who contract herpes and have weak immunity - the duration of treatment seven days, take 500 milligrams twice a day.  

[17], [18], [19]

Use Famvir during pregnancy

The use of the drug during pregnancy and lactating women has not been studied in detail and there has not been sufficient research. Therefore, the use of the drug during pregnancy and during lactation is not recommended. In extreme cases, a medicine can be used if the woman's health risk substantially exceeds all possible consequences.

Also, there are currently no publications on whether Famvir is given with breast milk from mother to child.

But there are experimental studies that show that penciclovir does not adversely affect the fetus.

Contraindications

It is necessary to be cautious about taking this medication, as there are the following contraindications to the use of the medication.

It is necessary to replace the antiviral medication if you have an increased sensitivity to one of the constituents of the medicine.

You should completely stop taking the medicine if you have hypersensitivity to penciclovir.  

[16]

Side effects Famvir

In carrying out a variety of clinical trials, the drug was well tolerated by different subjects. Side effects of the medication manifested themselves in extremely rare cases - these were either headaches or attacks of mild nausea. The following side effects may occur:

• Thrombocytopenia,
• Headache, small and rapid dizziness, drowsiness is possible.
• Weak nausea, it is possible vomiting in the elderly.
• Skin rashes, accompanied by mild itching and redness. 

Overdose

Overdosing can occur with the simultaneous administration of a large dose - more than ten grams. But, nevertheless, there are no serious clinical manifestations. The withdrawal of the medication occurs with hemodialysis, which can be used in extreme cases. The medicine is completely removed from the blood after four hours.

Interactions with other drugs

While conducting clinical studies of any significant indicator of pharmacokinetic interaction Famvir with other medications was not seen. Also, no effect on cytochrome systems was detected.

Medications that block the tubules can increase the level of Famvir in the blood.

[20], [21]

Storage conditions

The climatic conditions of the storage site of the medicine should provide for a dry place, which will be protected from direct sunlight and various light sources. The temperature at which the medicament will be stored should not exceed thirty degrees Celsius.

The storage area must be protected from children and pets. If the medicine is not to be used for a long time, the package should be well sealed, the blister with the tablets is not damaged. Otherwise, if the storage conditions are violated, the expiration date and the medicinal properties of the medicament are significantly reduced.

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Special instructions

Instructions for use

Famvir is an antiviral medication, therefore it is strictly forbidden to apply it independently without a doctor's diagnosis.

It is necessary from time to time to stop taking the medication once a year to be able to track the course of the disease.  

[23],

How to take Famvir?

The medication is designed to fight viral pathogens at the cellular level, so take the medicine before the infection is completely destroyed. For those who have strong immunity, the course of treatment is designed for a seven-day period. And those patients whose immunity is weakened after the disease, the elderly or children, the course of treatment can be extended to ten days. The medication intake does not depend on the time of day or food intake. But depending on the dose, can be broken down into several receptions per day.

Famweer Tablets

Famvir in the form of tablets, unlike ointment, fights against the virus in the body at the lowest - cellular level. Penetrating into and starting the transformation processes in human blood, Famvir tablets destroy viral DNA. And the stronger the dose, the longer your treatment will be, the higher the probability of complete recovery.

Famvir 500

Famvir 500 is the largest dose of the drug. It is prescribed to patients who have reduced immunity or in case of neglect of the disease. Also, famvir 500 milligrams can be prescribed for HIV-infected patients, since such patients have the most vulnerable immune system.  

[24], [25]

Famvir 250

Famvir 250 is the average dose of the drug. Famuse 250 is most often prescribed. The medication with this dose is administered several times a day by patients with primary viral infections. The course of admission Famvir 250 is usually a week.

[26]

Famvir 125

Famvir 125 is the lowest dose of this medication. Famvir 125 is prescribed from the first days of herpes detection or as an accompanying medication to treat a viral infection. The course is designed for several days. Famevir 125 may be taken as a prophylactic against repeated manifestations of viral infections.

[27],

Temvar Ointment

When a virus infection occurs, it is important not only to get rid of the internal problem - but also to eliminate external stimuli. In some cases, herpes can spread to the skin of the face (most often the virus wakes up on the lips). Therefore, it is necessary to carry out complex treatment - internal and external. Tablets will cope with the internal causative agent of herpes, and outside the viral infection will destroy the ointment. Ointment acts only on the infected skin area, destroys unpleasant symptoms and heals the wounds that remain after herpes on the skin.

Price

The price of the medicine can scare off some buyers, since it is higher than the average cost of antiviral drugs in the pharmaceutical market. But after the course of treatment with this drug, you can be sure that your body has got rid of a viral infection. 

Analogues

Antiviral drugs may have different components, but at the same time act on the causative agent of the disease. Analogues of the drug differ in price, producer country and active components. In addition, other drugs may have a different effect on the entire body, cause other reactions. At the moment, there are the following analogues of the drug Famvir: Minaker, Famciclovir, Famciclovir - Thera, Valaciclovir, Valtrex, Acyclovir. 

[28], [29], [30], [31]

Famvir or Valtrex

For those who do not know how to decide between drugs, you should pay attention first of all to the active components of the drugs, the cost and possible side effects. Both drugs have the same active substance - penciclavir. Medicinal drug Famvir passes more degrees of purification, accordingly has fewer side effects in contrast to Valtrex. 

[32], [33]

Famciclovir or Famvir

Those who choose between the drug Famciclovir or the drug Famvir need to know that this is the same drug that is represented by one active substance - penciclovir. Famvir is one of the trade names of the drug.

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Famvir or Acyclovir

When choosing between medicines, it is important not to choose between the price, but to choose, first of all, a more effective and harmless for the organism as a whole drug. Penciclovir has a deeper therapeutic effect, in contrast to acyclovir, an active ingredient in Acyclovir.

[35], [36], [37], [38], [39]

Reviews

The drug has mostly positive feedback among users and among doctors. Thanks to its active active substance, the fight against infection passes quickly and effectively - within ten days.

The only thing that can scare away the buyers before starting the drug is its price. But when treating for a viral infection, price is the last factor to be paid attention to. At the first place, of course, is the effectiveness and the minimum possible side effects. 

Shelf life

Under all conditions of storage, the medicine does not lose its therapeutic properties. But if for a long time the temperature at which the medication was stored or the high humidity in the room was kept, the sealing of the package was broken, the life of the medicament is shortened. Always check the expiration date before taking the medication.
Shelf life of the drug is thirty-six months from the date of manufacture.  

[40], [41]