Baktiflox-Lactab

Bactiflox-LACTAB is an antibacterial agent that belongs to the quinolone group. Let's consider the features of the drug, the method of application, dosage, possible side effects and contraindications.

Bactiflox-LACTAB has the international name ciprofloxacin. The drug is available in tablets, one tablet contains 291.5 mg of ciproflox tin hydrochloride, an active substance of tablets. Also, the composition of the medicine includes silicon dioxide, microcrystalline cellulose, magnesium stearate, crospovidone and other auxiliary substances.

Indications of the baktifloks-Laktaba

Indications for use are based on the action of the active substance of the preparation. Bactiflox-LACTAB is used to treat infectious diseases that are caused by sensitive strains of gram-positive bacteria. The drug is used to treat infections of the lower and upper respiratory tract, diseases of the genital organs and urinary tract. The medicine helps in the treatment of infectious diarrhea, lesions of the gastrointestinal tract and oral cavity.

Bactiflox-LACTAB is used for the treatment of infections of the joints, soft tissues and mucous membranes of the eyes. Antibacterial agent can be prescribed for the prophylaxis of infectious diseases in patients with reduced immunity. The medicine is active against pathogenic anthrax caused by Bacillus anthracis bacteria.

Release form

Form release - coated tablets of white color. Tablets have a round biconvex shape, with a fault line on one side. The active substance of the drug is ciproflox tin hydrochloride. The drug is available in two batches of Bactiflox 250 and 500, which contain 250 and 500 mg of the active substance.

This form of medicine has its advantages. Easy swallowing of tablets protects from a feeling of unpleasant taste and bitterness, practically does not cause irritation on the sensitive mucous membrane of the stomach. The medicine is issued in cardboard packages, in one package one blister of antibacterial agent for 10 tablets. Depending on the disease, the required dosage of Baktiflox-LACTAB and the individual treatment duration for each patient are selected.

Pharmacodynamics

Pharmacodynamics Baktifloks-LAKTAB allows you to learn about the processes that occur with the drug after use and how the active substance of an antibacterial agent copes with infectious diseases. Ciproflox belongs to the pre-fluoroquinolone group and acts as a synthetic bactericide with a wide spectrum of action. The drug is intended for re-use and is active against gram-negative and gram-positive microorganisms.

The peculiarity of the active ingredient Baktiflox-LACTAB is that it has resistance to other antibiotics, in addition to the medicinal groups belonging to the quinolone group. The drug is active against such microorganisms: Acinetobacter, Branhamella, Brucella, Citrobacter, Corynebacterium, Enterobacter, Plesiomonas, Salmonella, Serratia, Streptococus agalactiae, Staphyloccocus. Alcaligenes, Gardnerella, Mycobacterium fortuitum, Streptococus faecalis and pyogenes, Streptococcus viridans, Treponemapallidum.

Pharmacokinetics

Pharmacokinetics Baktifloks-LAKTAB are the processes of absorption, absorption, distribution, metabolism and excretion of the drug. The antibacterial agent is perfectly absorbed, the bioavailability of the drug is about 70%. The maximum concentration of Baktiflox-LACTAB in the blood is observed 1-2 hours after administration. Binding to blood proteins is at the level of 30%, and the average concentration of the active substance in the blood is observed 10-12 hours after administration.

The half-life of the drug in patients with normal renal function is about 4-6 hours. At the same time, 50% of the accepted dose of medicine is excreted unchanged in the urine. Patients with kidney disease should take a half dose of the drug and increase the time between doses of an antibacterial agent. Pay attention, the medicine is recommended to be taken before meals, otherwise absorption will be delayed by 1.5-2 hours, but this will not affect the overall absorption of the drug and its medicinal properties.

Dosing and administration

The mode of administration and dose of the drug are prescribed individually for each patient and depend on the infectious disease that is to be treated, the symptomatology and the contraindications to the reception of Bactiflox-LACTAB. Let's consider the standard dosage for infectious diseases, which treats this antibacterial drug.

•  Infectious lesions of the urinary tract (depending on the severity) - 125-250 mg, twice a day.
•  Infections of the upper and respiratory tract - 250 mg, twice a day.
• Severe infectious diseases (osteomyelitis and others) - 750 mg twice a day.
• When threatening infections in patients with cystic fibrosis, peritonitis or pneumonia - 750 mg, up to twice a day.

The duration of treatment with the use of Baktiflox-LACTAB should not exceed 14 days (60 days in case of especially severe infectious lesions).

Use of the baktifloks-Laktaba during pregnancy

Use of Baktiflox-LACTAB during pregnancy is prohibited. Any antibacterial and medicinal products fall under the ban. If a woman decides to take the medicine, then she must understand that the drug can cause the development of pathologies and abnormalities in her future baby.

Women who take antibacterial and anti-inflammatory drugs in the first trimester of pregnancy fall into the category of risk. The risk category implies a high probability of genetic and chromosomal abnormalities in the fetus. If urgent treatment of infectious diseases is necessary, doctors choose the safest medicines and analogues of Baktiflox-LAKTAB for pregnant women.

Contraindications

Contraindications to the use of Bactiflox-LACTAB are based on individual intolerance of the active substance of the drug. Ciprofloxacin is not recommended for use in patients with increased sensitivity to quinolone antimicrobials.

Bactiflox-LACTAB is not allowed during pregnancy and lactation. Antibacterial agents are not prescribed for children and adolescents who are under 18 years of age, since the growth phase has not been completed. In any case, the use of the medicine should be recommended by the attending physician and correspond to the medical indications.

Side effects of the baktifloks-Laktaba

Side effects occur due to non-compliance with the dosage of the drug or long-term administration. Adverse reactions of the body to the drug are extremely rare, but if they do occur, then, as a rule, it is: vomiting, abdominal pain, diarrhea, headache, flatulence, loss of appetite and digestive disorders.

In some patients, taking Baktiflox-LACTAB can cause hypotension, rapid heart rate, allergic skin rashes or muscle pain. If there is a side effect of the drug, it is recommended to reduce the dose of antibacterial agent and seek medical help.

Overdose

Overdose can occur because of prolonged treatment, the use of increased dosage or use of a drug in which the storage conditions were violated or expired. In case of an overdose, there may be toxic kidney damage (reversible) and symptomatology, which manifests itself as side effects of an antibacterial agent.

In order to avoid overdose, Baktiflox-LACTAB is given with special care to elderly patients, people with central nervous system disorders, a tendency to spasms and epileptic seizures. Do not forget that the reactions of the central nervous system to the drug are individual for each patient. One of the side effects of Baktiflox-LACTAB is the effect on the ability to control mechanisms and vehicles. Therefore, when treating this antibacterial agent is recommended to comply with all the rules prescribed in the instructions of the drug.

Interactions with other drugs

Interactions with other drugs are possible only on medical advice and permission of the attending physician. The drug is not recommended to be taken simultaneously with antacids, which contain aluminum or magnesium hydroxide, since this interaction reduces the bioavailability of ciproflox by 90%. Therefore, the drugs are recommended to take at intervals of 4 hours.

The same effect is observed in the interaction of Baktiflox-LACTAB with preparations of aluminum-containing sucralfates. When this antibacterial agent is used with theophylline, an increase in serum levels of the latter occurs, which leads to negative reactions from the central nervous system.

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Storage conditions

The storage conditions are indicated in the instructions and correspond to the storage conditions of antibacterial and anti-inflammatory agents. Tablets should be stored in a dry, cool place that is inaccessible to children and protected from sunlight. Storage temperature should not exceed 30 ° C.

If the storage conditions of Baktiflox-LACTAB are not respected, the medicine loses its medicinal properties. In addition, the drug loses its physical properties, the tablets may change color or begin to crumble. In this case, Baktifloks-LAKTAB must be disposed of. 

Shelf life

The shelf life of Baktiflox-LACTAB is five years from the date of manufacture, which is indicated on the medicine package. One of the rules for preserving such a long shelf life of an antibacterial agent is observance of the conditions of its storage. At the expiration date, the drug is not allowed, as this can cause uncontrolled adverse reactions from the gastrointestinal tract and central nervous system.