Bactyl

Bactyl is an antimicrobial drug that belongs to the second generation cephalosporins. Let's consider the main indications for the purpose of the drug, dosage, contraindications and side effects. Bactyl is a drug whose effectiveness is to inhibit the synthesis of harmful microorganisms, which leads to their death and destruction.

Indications Bactyl

Indications for use Bactyl are based on the action of the active substance of the drug. Bactyl is prescribed for the treatment of infectious diseases and oppression of harmful microorganisms that are sensitive to the action of cefuroxime.

Bactyl is prescribed for infectious diseases of the respiratory system, bronchi, lungs and ENT organs. The drug helps in the treatment of infectious lesions of the urogenital tract. The drug is active in infectious lesions of soft tissues and skin. The antimicrobial is effective against Lyme disease (skin and nerve endings by infectious microorganisms).

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Release form

The form of the release of Bactyl is a tablet. The drug is released in a dosage of 250 and 500 mg of the active ingredient. Tablets are sold in a strip-packing, in each package there is a plate with tablets Bactile. The active substance of the drug is cefuroxime axetil. Excipients: sodium lauryl sulfate, Magnesium stearate, Cellulose microcristallic, croscarmellose sodium and others.

The tablet form of release Bactile allows to calculate the course of treatment. And the opportunity to choose a suitable dosage of 250 and 500 mg of cefuroxime makes it possible to choose the most effective and quickest way to treat an infectious lesion.

Pharmacodynamics

Pharmacodynamics Bactyl is the biochemical effects that occur with the drug after administration. The active substance of the drug is cefuroxime. Cefuroxime is a preoral form of a cephalosporin antibiotic of bactericidal action. The drug is active against beta-lactamases, Gram-positive and Gram-negative microorganisms.

The drug is active against gram-negative and gram-positive aerobes and anaerobes. The work of the drug consists in suppressing the synthesis of the drug. Bactyl is not active against: Clostridium difficile, Campylobacter spp., Acinetobacter calcoaceticus, Legionella spp., Morganella morganii, Enterobacter spp., Citrobacter spp., Vacteroides fragilis.

Pharmacokinetics

Pharmacokinetics Bactyl is a process that occurs with a drug in the human body. Cefuroxime is absorbed in the gastrointestinal tract and hydrolyzed on the intestinal mucosa. After absorption, the drug enters the circulatory system. The drug is recommended to be taken 30 minutes after eating, since it is at this point that the maximum level of absorption is observed.

The maximum level of Bactyl in the serum is observed three hours after admission. Binding to blood proteins is at the level of 35%, and the elimination half-life is 1.5 hours. Drug is excreted by the kidneys. The level of active substance in the blood serum decreases due to dialysis.

Dosing and administration

The way of application and dose of Bactyl are individual for each patient, therefore they are selected by the doctor. The dosage depends on the age of the patient, the disease that is treated and the symptomatology manifested. The drug is taken by mouth, after eating. Such a method of administration provides a good absorption of the drug. The course of treatment with Bactile should not exceed ten days.

• When infectious diseases in adults, it is recommended to take 250 mg of the drug twice a day. When the genitourinary system is damaged, 125 mg twice a day. With inflammation of the bronchopulmonary system, 500 mg of Bactyl are prescribed twice a day for 20 days. It is recommended to take the drug consistently, gradually increasing the dosage of the drug.
• When infectious diseases in children, Bactile is taken at 125 mg twice a day, with the maximum available dosage is 250 mg. In the treatment of otitis and serious infections, Bactyl take 250 mg twice a day, the maximum dose of the drug is 500 mg.

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Use Bactyl during pregnancy

Bactyl use during pregnancy is possible only for medical reasons, when the therapeutic benefit for the mother is much more important than the potential risk of normal, full development of the child.

The drug is contraindicated for use in the first trimester of pregnancy. This is due to the fact that it is in the first months of pregnancy that all the vital organs of the baby are formed. If the drug is prescribed for use in the second and third trimesters of pregnancy, then the woman requires special care. Bactyl is not recommended during breastfeeding, as the drug penetrates into the mother's milk.

Contraindications

Contraindications to the use of Bactyl are based on increased sensitivity to the active substance of the drug. With special care, the drug is prescribed for patients with impaired renal function, gastrointestinal tract and when the body is depleted. The drug is prohibited for children under three years of age in a tablet form of release. With long-term treatment, Bactile causes growth and development of insensitive flora (enterococci, candida).

If the drug is taken by patients with weakened immunity, then the development of diarrhea is possible. Please note, when taking Bactyl, it is forbidden to operate machinery and vehicles, as the drug causes severe headache, dizziness and even hallucinations.

Side effects Bactyl

Side effects of Bactyl are possible if the drug is used by patients who have contraindications to its use. Adverse symptoms may also occur if the dosage is not met or because the recommended treatment period is exceeded. With increased sensitivity to the active substance Bactyl, allergic reactions, urticaria, pruritus, toxic erythema begin in patients. In this case, you must abandon the use of the drug.

With dyspeptic adverse reactions, pseudomembranous colitis, elevated liver enzymes and stool disorders, Bactile should be discontinued. Very often, side effects of Bactile are manifested in the form of headaches, low levels of leukocytes and platelets, dizziness, apathy.

Overdose

Overdose Bactile occurs in patients who have exceeded the recommended dosage of the drug. In this case, the patients are observed neurological changes, which are accompanied by convulsions. Anticonvulsants are used to treat this overdose symptom.

Overdose Bactile may occur with long-term treatment with the use of the drug. In severe cases of overdose, for effective care, patients undergo peritoneal hemodialysis.

Interactions with other drugs

Interaction Bactyl with other drugs is possible only if the drug is included in the complex treatment and the attending physician approved the simultaneous use of several drugs. If Bactylyum is taken with drugs that suppress the secretion of gastric juice, the absorption efficiency of Bactyl decreases.

Note that if Bactile's patient is given a glucose oxidase test for blood sugar, false positive reactions are possible. When the drug interacts with anti-arthritis agents, for example, probenecid, the blood levels of cefuroxime in the blood are increased by 50% of the initial value. In this case, patients have severe symptoms of overdose and drug poisoning.

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Storage conditions

The storage conditions of Bactyl correspond to the storage conditions of the medicinal preparations of the tabletted form of release. Bactyl must be stored in a dry place, protected from sunlight and inaccessible to children. The storage temperature of the preparation should not exceed 25 ° C. Store Bactyl only in its original packaging and avoid storing the drug in a humid room.

If the storage conditions of Bactyl are not respected, the drug loses its medicinal properties and may cause side reactions and symptoms of an overdose.

Shelf life

Shelf life Bactile is two years from the date of manufacture of the drug, which is indicated on the package of the medicinal product. After the expiration date, Bactyl must be disposed of. Take the drug with an expired shelf life or a drug whose conditions have not been met, is categorically contraindicated.