Tazan

Teraflex helps to restore cartilage tissue.

Indications Teraflex

It is used to treat diseases of the joints - osteochondrosis or osteoarthrosis.

[1]

Release form

The release of the drug is made in capsules in the amount of 30, 60 or 100 pieces inside the bottles of polyethylene.

Pharmacodynamics

Glucosamine hydrochloride with chondroitin sulfate promotes the binding of connective tissues and also prevents cartilage damage.

The use of glucosamine helps to protect the diseased cartilage from the subsequent destruction, which may appear in the case of the use of NSAIDs and GCS, and also leads to the development of moderate anti-inflammatory activity.

Chondroitin sulphate is a substance that helps build cartilage, and besides it promotes the binding of proteoglycans, collagen and hyaluronic acid. At the same time, the component provides the required viscosity of the synovium, inhibits the properties of enzymes that destroy cartilage, and heals the cartilage tissue. In the case of treatment of osteoarthritis, it can reduce the amount of NSAIDs used and alleviate the symptoms of the pathology.

Pharmacokinetics

After applying glucosamine inside, its bioavailability values are approximately 25%. The highest component rates are found inside the liver, articular cartilage and kidney. The element can persist for a long time inside the bone and muscle tissues. Half-life is approximately 3 days. Excretion occurs to a greater extent through the kidneys.

The bioavailability of chondroitin sulfate is approximately 12%. The exchange processes inside the body occur through desulphurisation reactions. Excretion is carried out through the kidneys, the half-life of the component is 5 hours.

[2]

Dosing and administration

Adolescents from 15 years old, as well as adults are required to consume 1 capsule 3 times a day for the first 3 weeks, and then 2 times a day for a period of 3-6 months. Repetition of therapeutic cycles is allowed.

You can use capsules at any time of the day, without reference to food intake. It is necessary to wash down the medicine with a small amount of plain water.

[5]

Use Teraflex during pregnancy

Since there is no information on the use of Teraflex during pregnancy or lactation, it is forbidden to take it in this period.

Contraindications

Main contraindications:

• kidney failure in severe severity;
• the presence of hypersensitivity to the elements of the drug.

If a patient has a predisposition to bleeding, and besides diabetics and people with BA, the medicine should be prescribed with caution.

[3]

Side effects Teraflex

The use of medication may lead to the occurrence of certain side effects:

• digestive disorders: obstipation, diarrhea, bloating and stomach pain;
• HC activity disorders: headaches, drowsiness or insomnia, as well as dizziness;
• Other manifestations: increased heart rate, swelling and pain in the legs, as well as allergies.

[4]

Overdose

No drug poisoning was noted; if such a reaction develops, gastric lavage is required.

[6]

Interactions with other drugs

The drug enhances the absorption of tetracyclines, and in addition it weakens the therapeutic efficacy of chloramphenicols, as well as semi-articulated penicillins.

Chondroitin can potentiate the medicinal effects of anticoagulants.

[7], [8], [9]

Storage conditions

Teraflex must be kept in a place closed to children. Temperatures - within the mark of 25 ° C.

Shelf life

Teraflex allowed to apply within 36 months from the date of manufacture of the pharmaceutical product.

Application for children

Cannot be prescribed for use in children under 15 years of age.

[10]

Analogs

Analogues of the drug are the drugs Hondrogard, Kondronova, Hondroksid, Artra with Struktum, Don, Hondrogluxid with Mucosate and Glucosamine Chondroitin complex.

Reviews

Teraflex gets pretty mixed reviews on medical forums. There are both completely positive comments and opinions that the medicine is absolutely useless. In many patients after the passage of the treatment cycle, the disappearance of the crunch and pain in the joints, as well as the increase in their mobility, was noted. But at the same time, those people with whom the drug helped, mark such a minus as the relatively high cost.

Doctors also respond differently about the medicine - someone gives him a positive assessment, and some consider it not very effective.

From all this, you can derive such an assessment - Teraflex demonstrates the most noticeable effectiveness with prolonged use (at least six months), as well as with not running the stages of pathology. In addition, an important advantage of the drug is that it can be combined with anti-inflammatory drugs and other therapeutic methods, as well as used for monotherapy.