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Health

Sodium Fluoride

, medical expert
Last reviewed: 23.04.2024
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Sodium Fluoride is used to prevent the development of caries.

trusted-source[1], [2], [3], [4], [5], [6], [7], [8]

Indications of the sodium Fluoride

It is used as a preventive preparation against caries, and in addition it can be prescribed for the treatment of osteomalacia, osteoporosis, myeloma, metastasis of a diffuse nature in the bone tissue region, and in addition, with strong fragility of the bones of a congenital nature.

trusted-source[9], [10], [11]

Release form

The release is carried out in tablet form, 250 pieces inside the bottle (1 such bottle inside the package).

Sodium fluoride with orange flavor

Sodium fluoride with orange flavor is prescribed for children. Release occurs on 10 tablets inside the blister plate. In the package there are 3 such blisters.

trusted-source[12], [13], [14]

Pharmacodynamics

Sodium Fluoride promotes the process of mineralization of teeth, and at the same time helps to form tooth enamel. The medicine has bactericidal properties and interferes with the development of caries.

The use of the drug helps to reduce the resorption processes inside the bone tissue. And when combined with calcium, as well as cholecalciferol, it contributes to bone calcification.

trusted-source[15], [16]

Pharmacokinetics

The active ingredient is well absorbed from the digestive tract. But it must be taken into account that the calcium / magnesium salts, as well as aluminum, weaken the absorption of drugs. Peak plasma values are noted after 4 hours after oral administration of the drug.

Fluorides are cumulated inside the body, mostly inside the bones with teeth, as well as nails and hair.

Excretion occurs mainly with urine. In addition, the medicine is excreted with saliva and feces.

trusted-source[17], [18], [19], [20], [21], [22], [23]

Dosing and administration

For children 2-6 years of age, the medication in tablets with a volume of 1.1 mg is prescribed on the first day. The older children's age is allowed to appoint a daily single dose in the amount of the 1st pill with a volume of 2.2 mg or 2 tablets with a volume of 1.1 mg.

It is recommended to take the medicine before going to bed, after the teeth are cleaned. Use is done orally - you should hold the tablet in your mouth until it completely resolves. Last such reception should not be less than 250 days / year. It is advisable to take the medicine every year until the teenager reaches the age of 15 years.

trusted-source[29], [30], [31], [32],

Use of the sodium Fluoride during pregnancy

Do not prescribe the drug to pregnant women.

Contraindications

The main contraindications:

  • the presence of hypersensitivity to the elements of the drug;
  • exacerbated ulcer inside the gastrointestinal tract;
  • infants up to 2 years of age;
  • lactation period;
  • myxedema;
  • kidney / liver failure;
  • consumption of drinking water, which contains a high level of fluoride (more than 0.7 mg / ml).

As part of the tablets with orange flavor, the substance aspartame is contained, so they are forbidden to appoint persons with phenylketonuria. The absorbable tablets contain lactose, which is why they can not be taken with the congenital form of galactose intolerance, and in addition, with malabsorption syndrome or lactase deficiency.

trusted-source[24], [25], [26]

Side effects of the sodium Fluoride

Basically, the drug is tolerated by patients without complications. Occasionally, there are some side effects: vomiting, fluorosis, diarrhea, and nausea. However, allergy symptoms can be observed - rashes, eosinophilia and runny nose.

As a result of prolonged use of drugs, osteosclerosis, visual disturbances, headaches, arthritis, increased fatigue, and also ossification in the area of attachment of ligaments to tendons occur.

trusted-source[27], [28]

Overdose

Lethal dosage of medication for an adult is a single dose of 5-10 g. However, severe consequences can be expected even in case of taking a portion up to 1 g for one use.

Because of the poisoning of sodium fluoride inside the body, a high index of hydrofluoric acid, which has an irritant effect on the gastrointestinal mucosa, is observed. At the same time, there is a disruption in the processes of exchange and electrolyte balance. There is also a development of hypocalcemia.

As a result of taking excessively high portions of drugs, the following negative reactions can occur: dizziness, abdominal pain and diarrhea with nausea. In addition, severe fatigue or excitability, an increase in temperature, tremor, respiratory insufficiency, and stopping of respiratory processes develop. There may be a feeling of weakness or drowsiness, vomiting (ordinary and with blood), hypersalivation, tremors, stomach cramps, pain in the legs, worsening of appetite, lacrimation, visual disturbance and arthralgia.

To eliminate intoxication, the affected stomach should be washed using calcium chloride (1-5% solution) or calcium hydroxide (0.15% solution). In addition, diuretics and saline purgatives are prescribed for the patient. To reduce the degree of absorption of fluorides, aluminum hydroxide is used. It is necessary to slowly enter IV in a 10-20% solution of calcium gluconate. Together with this, the patient is prescribed hemodialysis and the use of vitamins. There are also procedures aimed at eliminating the symptoms of the disorders.

With chronic poisoning fluorosis is observed in the area of teeth and bones. There is an increase in the density of bone tissue, and in addition, calcification of ligaments with tendons. These people are marked by a darkening of the color of tooth enamel, restriction of mobility, and also deformation with joint pain.

trusted-source[33], [34], [35], [36], [37]

Interactions with other drugs

The drug is not allowed to be combined with any medicinal product, the constituent elements of which are calcium or aluminum hydroxide. If these medicines need to be taken, you should do this a few hours before using Sodium Fluoride.

The use of retinol or calciferol in combination with the drug may cause the development of calcification of an ectopic nature.

trusted-source[38], [39]

Storage conditions

Sodium fluoride is required to be kept in a dark place, protected from moisture and access to small children. The temperature should not exceed 25 ° C.

trusted-source[40], [41], [42]

Special instructions

Reviews

Sodium fluoride is often prescribed as a tool to help form the enamel on the teeth, as well as to promote their mineralization. The reviews demonstrate that the drug has a very effective preventive effect against the development of caries, and also eliminates diffuse type metastases developing in bone tissues, as well as osteoporosis, plasmacytoma and osteomalacia. Among the benefits of the drug is also that in most cases it is well tolerated by patients.

trusted-source[43], [44],

Shelf life

Sodium fluoride can be used for 5 years from the date of release of the drug.

trusted-source

Attention!

To simplify the perception of information, this instruction for use of the drug "Sodium Fluoride" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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