Nazonex in adenoids in children: how to correctly pshikat, treatment regimen

Nazonex in adenoids in children is one of the drugs that is used today as a drug of choice. The effectiveness of this tool is studied in many studies and is proved in practice. To explain the effect of the drug, it is important to know the mechanism of its action and indications.

What are adenoids and how does it work?

Adenoids are a chronic disease characterized by an increase in the pharyngeal tonsil, which leads to a complicated nasal breathing and other similar symptoms. This condition constantly worries the child and in viral infections the amygdala increases even more, which disrupts the normal breathing of the child. The amygdala is an accumulation of lymphoid tissue that reacts to an infectious agent and is part of the local immune defense of the body. Influence on the immune system of the child is very difficult, therefore treatment of adenoids always caused difficulties.

To date, the treatment of adenoids is recommended to begin with intranasal corticosteroids. To explain the decrease in adenoids under the influence of these drugs, several mechanisms are proposed: direct lympholytic action, suppression of inflammation with reduction of concomitant edema of adenoids, and also indirect influence on the nature of adenoid microflora. It has now been proven that intranasal corticosteroids can reduce the symptoms of adenoids, regardless of the atopic status of the child. And even if the child does not have allergic rhinitis, the use of such treatment can reduce the degree of hypertrophy of the pharyngeal tonsil.

For the purpose of such local treatment, many intranasal hormonal preparations can be used, one of which is Nazonex. The mechanism of action of this drug in adenoids is to reduce edema and reduce sensitization of the pharyngeal tonsil. This leads to a decrease in its activity and, correspondingly, to a decrease in its size.

Indications of the nasonex in adenoids in children

NAZONEX is a drug whose active ingredient is the hormone drug mometasone furoate. It is a glucocorticoid in the form of a local remedy for the treatment of adenoids and other pathologies of ENT organs. Indications for use of Nazonex are not limited to adenoids. The drug is also indicated in the complex treatment of acute sinusitis and allergic rhinitis, as well as for the prevention of exacerbations in seasonal allergic rhinitis.

[1], [2], [3]

Release form

The form of release of a preparation for local treatment is a spray in a nose with a special nozzle which is removed. One bottle of spray contains 120 doses of the drug. This form of release allows you to act precisely in the nasopharynx and reduces the risk of systemic manifestations from the use of hormonal means.

The names of the drug can be - "Nazonex" or "Nazonex sinus", they are identical drugs.

[4], [5]

Pharmacodynamics

Pharmacodynamics Nazoneksa lies in its local action on the mucous membrane of the nasal cavity. The drug is a synthetic hormone that gets on the mucous membrane reduces the synthesis of leukotrienes and other mediators of inflammation. This, in turn, reduces the manifestations of allergic hypersensitivity in the nasal cavity.

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Pharmacokinetics

Pharmacokinetics - the drug is absorbed into the blood in a minimal amount in case of accidental ingestion during inhalation. The remainder of the drug from the intestine is excreted through the bile and kidneys. The systemic effect of Nazonex was not detected with proper application and accurate dosing.

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Dosing and administration

The method of application of the drug is only intranasal. Doses for children from the age of two years are 50 micrograms per application. Use the drug once a day by inhalation in the nose of a single dose of spray, which corresponds to 50 micrograms. The course of treatment should be three to four weeks.

Contraindications

Contraindications to the use of Nazonex are limited to those cases when the child was operated in the nasal cavity or if there were earlier allergic reactions to such a drug. Children up to two years of the drug also can not be used. In the presence of an acute purulent process in the nasal cavity without treatment with other drugs, it is also impossible to use Nazonex, since it inhibits the inflammatory process.

Side effects of the nasonex in adenoids in children

Side effects are more often found in the form of local manifestations due to the lack of systemic influence. Such side effects include nasal bleeding, sensation of itching and perspiration in the nasal cavity, sneezing, nosebleeds. The systemic manifestations include headache, which occurs most often. With prolonged use of the drug and excess dosage, there is a decrease in local immunity and a tendency to ulceration of the mucosa.

[8]

Overdose

An overdose of a medicine is very rare, as only local spray application is provided, which minimizes systemic influences. If the drug was taken incorrectly or there was an occasional excess of the dose, adrenal insufficiency may develop.

[9], [10]

Interactions with other drugs

Interaction with other drugs shows that the use of Nazonex with funds against allergies of local and systemic nature does not affect the metabolism of both groups of drugs. The use of other groups of drugs, together with Nazonex, has not been studied.

[11], [12]

Storage conditions

The storage conditions of the medicine do not differ from those in the case of storage of any other medicines - it is recommended to store at room temperature and do not freeze the bottle. 

Shelf life

The shelf life is limited to three years, but there may be individual storage conditions, which depends on the manufacturer, so you need to consult the instructions.

[13]

Reviews

Reviews about Nazonex in the treatment of adenoids are noted only positive. Many parents say that the symptoms decrease after the first course of treatment. Very often it is possible to reduce the degree of enlargement of the tonsils by one gradation, which sometimes makes it possible to avoid surgery.

Nazonex in adenoids in children can be used as a preparation of the main line of treatment. The drug, due to its anti-inflammatory and anti-allergic properties, reduces the sensitivity of the amygdala and it decreases in size. If you combine Nazonex with other conservative methods, the effect and prognosis of treatment is very good.