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Belosalik lotion
Last reviewed: 23.04.2024
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The combined preparation Belosalik lotion refers to topical corticosteroid agents used in dermatology to relieve inflammation, irritation, desquamation and pruritic skin.
Indications of the belosalika lotion
Belosalik lotion is intended for symptomatic treatment of chronic dermatoses with increased keratinization of epithelial keratinocytes and their desquamation (sluschivaniem): allergodermatosis (atopic dermatitis, urticaria, eczema); seborrhea and seborrheic dermatitis of the scalp; diffuse keratoma (ichthyosis); psoriasis of the scalp.
Release form
Belosalik lotion - solution in vials of 50-100 ml (with a dropper or nozzle for spraying) - only for external use.
Pharmacodynamics
The therapeutic effect of Belosalik lotion is provided by its active components - the synthetic homon of the adrenal cortex (corticosteroid) betamethasone in the form of dipropionate and salicylic (2-hydroxybenzoic) acid.
Betamethasone with external application promotes the removal of inflammatory, allergic and hyperproliferative skin reaction by binding to cell receptors and their DNA, which increases the synthesis of the lipocortin protein that inhibits the activity of the intracellular enzyme phospholipase A2. A further mechanism consists in blocking the release of arachidonic and lysophosphatidic acids and subsequent modification of their cyclooxygenases (COX 1 and COX 2) into active compounds - anti-inflammatory and inflammatory mediators (eicosanoids, prostaglandins, leukotrienes).
In addition, glucocorticosteroids (GCS), including betamethasone dipropionate, inhibit the synthesis of T- and B-lymphocytes, tissue immunoglobulins (IgE and IgG), and also reduce the yield of histamine from mast cells, which alleviates the symptoms of an allergic reaction.
Salicylic acid in the composition of Belosalik lotion acts as an antiseptic and keratolytic, that is, does not allow the infection to develop and soften the keratinized skin particles.
Pharmacokinetics
A small amount of betamethasone in the lotion Belosalik enters the bloodstream and binds to proteins; biotransformation of GCS occurs in the liver, and metabolites are excreted in the urine and feces.
Dosing and administration
Belosalik lotion is used externally by spraying the solution on the inflamed areas of the scalp skin - once or twice during the day.
The maximum duration of use should not exceed three consecutive weeks.
Manufacturers warn about the inadmissibility of getting the drug in the eyes, on the mucous membranes and genitals.
Use of the belosalika lotion during pregnancy
Salicylic acid is contraindicated for pregnant women, in addition, there is no evidence of safety of topical corticosteroids for intrauterine development of the fetus. Therefore Belosalik Lotion during pregnancy is not used.
Contraindications
Belosalik lotion is contraindicated to use if available:
- hypersensitivity to GCS and salicylates;
- skin lesions of bacterial, viral or fungal origin;
- acne and rosacea;
- purulent inflammatory foci and ulcers on the skin;
- skin irritations after vaccination;
- any skin problems in children of the first six months of life.
Side effects of the belosalika lotion
Among the side effects of Belosalik Lotion are noted:
The appearance of a skin reaction - redness, rashes, burning and itching;
- increased dryness of the skin;
- formation of striae;
- inflammation of hair follicles and hepitrichiasis;
- thinning of the epidermal layer of the skin and its atrophy;
- accession of secondary infections.
Long-term use of this product, as well as large areas of its use, can cause the skin capillaries to expand, increase arterial and intracranial pressure, hyperglycemia and glucosuria, dyspepsia, impairment of fat and protein metabolism in the body, demineralization of bone tissue-that is, systemic side effects of SCS.
[1]
Overdose
In case of exceeding the dose of Belosalik Lotion, systemic side effects of glucocorticosteroids develop - insufficiency of the adrenal cortex and hypercorticoid syndrome. The use of this remedy should be stopped immediately and consult a doctor.
Storage conditions
Belosalik lotion is recommended to store at normal room temperature in a place inaccessible to children.
Shelf life
24 months.
Attention!
To simplify the perception of information, this instruction for use of the drug "Belosalik lotion" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.