Agiflux

Adjiflux is a combination medicine. Consider the features of its use, contraindications, dosage and other rules of instruction.

The drug is prescribed for patients with various diseases of the gastrointestinal tract. The therapeutic effect is due to the components that make up its composition. The drug has antacid (neutralizing the acid of gastric juice), adsorbing (absorption of the surface layer of the gastrointestinal tract of various substances from gases and liquids), enveloping, choleretic and carminative properties.

Indications Agiflux

Treatment of diseases of the digestive tract is a long process that involves not only medication, but a special diet and lifestyle changes. Drugs are selected, focusing on the severity of the disease and the individual characteristics of the patient's body.

Consider the indications for the use of Adjuxlux:

• Gastritis (acute, hyperacid)
• Acute duodenitis
• Ulcerative lesions of duodenum and stomach
• Erosion of the mucous membrane of the upper gastrointestinal tract
• Acute pancreatitis and phases of its exacerbation
• Symptomatic Ulcers
• Reflux-esophagitis
• Hyperphosphatemia
• Hernias of the esophageal opening of the diaphragm
• Heartburn
• Gastralgia
• Putrefactive or fermental indigestion
• Hyperphosphatemia

The drug is dispensed according to the prescription.

Release form

Adjiflux has a tabletted form of release, and also comes in the form of a gel and a suspension. One chewable tablet contains: 400 mg of aluminum hydroxide gel dry and 400 mg magnesium hydroxide. Auxiliary components are: sucrose, povidone, sorbitol solution, sodium saccharin, silicon dioxide colloid, peppermint oil, magnesium stearate.

Tablets are white, round, flat, sweet to the taste. In one carton pack two blisters for 10 tablets.

Pharmacodynamics

The mechanism of action of the drug is based on the effectiveness of the components in its composition. Pharmacodynamics of magnesium hydroxide indicates its laxative effect, the algebra has absorptive, enveloping and antacid properties.

The drug neutralizes free HCl in the gastrointestinal tract, reducing the activity of gastric juice. Binds the bile acids that enter the stomach due to reflux from the duodenum, and inactivates pepsin. Has a protective effect on the gastrointestinal tract, accelerates the motility of all its departments. Does not cause alkalosis and secondary hypersecretion of HCl.

Pharmacokinetics

Agiflux has a low absorption. The therapeutic effect occurs within 15-30 minutes after application. Pharmacokinetics of the drug has not been studied in detail. 

Dosing and administration

To effectively treat various pathologies of the gastrointestinal tract, the method of application and dose of Adjiflux is selected by the attending physician. As a rule, patients are prescribed 2-3 tablets 1-2 hours after meals or before bedtime. With a peptic ulcer, pills are taken 30 minutes before meals. If necessary, a single dosage can be increased to 3-4 pieces per day. After achieving the desired therapeutic effect, maintenance therapy is shown - 1-2 tablets a day for 2-3 months.

To improve the effectiveness of the drug, it is recommended to chew the capsules or dissolve until complete dissolution. Before using the suspension or gel, the vial of the drug should be shaken well, that is, homogenize.

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Use Agiflux during pregnancy

The possibility of using Adjaflux during pregnancy is determined by the attending physician, focusing on the condition of the woman's organism and the possible risks to the fetus. It is used with extreme caution when breastfeeding, as active ingredients can penetrate into the mother's milk.

Contraindications

The drug is contraindicated for use with individual intolerance to its components, Alzheimer's disease, hypophosphatemia, chronic renal failure, and pregnancy. With special care is prescribed for patients younger than 12 years and during lactation.

Side effects Agiflux

Incorrect use of the drug may cause side effects. Adjiflux often provokes attacks of nausea and vomiting, constipation, changes in taste sensations. Prolonged use of high dosages is dangerous by the development of hypophosphatemia, hypercalciuria, osteoporosis, osteomalacia, hypocalcaemia, encephalopathy, impaired renal function.

If the tablets are prescribed to patients with renal insufficiency, there is a risk of lowering blood pressure, increased thirst and dry mouth, hyporeflexia.

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Overdose

The use of increased doses of medication can trigger unwanted overdose reactions. Patients encounter such symptoms: muscle weakness, increased fatigue, decreased tendon reflexes, osteoporosis, abdominal pain and intestinal obstruction, encephalopathy, cardiac arrhythmias, skin allergic reactions.

Treatment is symptomatic, and it is necessary to stop further use of the drug and seek medical help.

Interactions with other drugs

Adjiflux can cause side reactions when interacting with other drugs. In order to prevent this, all medications should be monitored by the attending physician. Tablets slow down and decrease the level of absorption of Digoxin, Indomethacin, Phenytoin, H2-histamine receptor blockers, tetracycline antibiotics, indirect coagulants, beta-blockers. When used with M-holinoblokatorami, slows down the emptying of the stomach, strengthens and lengthens the action of Ajfluks. 

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Storage conditions

According to the storage conditions, the tablets should be kept in a dry place, protected from sunlight and inaccessible to children. Recommended storage temperature is not higher than 25 ° С. Failure to observe storage conditions leads to premature damage to the medicine.

Shelf life

Adjiflux is authorized for use within 60 months from the production date. Shelf life is indicated on the product package. At its expiration, the drug is contraindicated to be used for medicinal purposes and must be disposed of.