Effective psoriasis tablets

This disease has been studied for a long time and until now its causes remain unknown. Treatment of scaly lichen (also called psoriasis) is very individual.

[1], [2], [3], [4]

Indications of the psoriasis tablets

Indications for the use of all the means listed below include psoriasis of varying severity. Begin treatment with more easily tolerated drugs that have a minimal side effect. If relief does not come, go to more powerful, and, at the same time, far from innocuous means.

Release form

Drugs that help to forget about the exacerbations of the disease for a long time belong to completely different pharmacological groups and, nevertheless, they are all used to eliminate psoriatic rashes.

Psoril

Pharmaceutical homeopathic preparation Psorilom, contains a complex of components that relieve the symptoms of exacerbation of psoriasis. Patients with lesions that capture not more than a fifth of the entire surface of the skin can use it as the main mono drug. With a larger area of rashes Psoril is used as an additional remedy in combination with other medicines.

Pharmacodynamics of the drug is determined by its composition, which includes natural components in homeopathic dilutions, which prevents serious side effects.

Produced in the form of tablets, packaging is very diverse from 10 to 200 pieces; sugar granules - from 15 to 50 g in a jar.

The graphite, which is part of the medicine, helps to eliminate cracks and eruptions, the golden rod complements this action and relieves burning sensation. Exfoliation of pustular plaques is carried out by barberry, along with antipruritic action. Potassium bromate struggles with all manifestations of psoriasis in the areas of hair. Salicylic acid has an effective anti-inflammatory and disinfecting effect, zinc pyrithione is drying the wounds, however, their dosages in the composition are negligible and side effects can be neglected.

This drug can also be used during remission to prevent exacerbations. However, despite all the apparent safety of Psorilom, it should not be used during pregnancy and lactation, and also for the treatment of children.

Contraindicated in allergies to its ingredients. Occasionally, it can cause sensitization.

Method of application - sublingual, three times a day (tablet form - 1 unit, granular - 8 units). The duration of the course of therapy from two to three months, after a month's break, you can re-take.

Clinical consequences of overdose and interaction with other drugs are not registered.

Keep no more than five years, observing the temperature regime of 15-25 ° C.

[5], [6], [7]

Neotigazon

A dermatotropin drug Neotigazone is used for severe degrees of dermatoses, including psoriatic skin lesions. Active component of the drug - acitetrine (synthesized retinoic acid), normalizing the processes of cell growth and development.

Produced in capsules of 10 mg, sealed in blisters of ten pieces, packed in three, five or ten blisters.

Normalizes the rate of reproduction and death of skin cells, revitalizes their structure, exfoliates.

Pharmacokinetics: when ingested in the gastrointestinal tract, Neotigazone is well absorbed into the tissue, the maximum concentration is achieved within one to four hours. Bioavailability (≈60%), increases when consumed simultaneously with food or after eating. Almost completely binds to albumins.

Excretion of the main part of the Neotigazone (≈99%) occurs within five weeks in the form of metabolites with urine and bile in equal amounts.

In some organisms, the formation of tigazone occurs, in these cases, complete excretion is prolonged to two years after the end of treatment.

Contraindicated in pregnant and lactating women, as it overcomes the placental barrier and is found in breast milk, as well as with allergies to derivatives of carotenoids and retinoids, hepatic and renal dysfunction.

The undesirable effects of taking Neotigazone are expressed in the appearance of signs of hypervitaminosis A.

The route of administration is taken orally together with food or milk once a day. The initial dosage for adults is 0.025-0.03 g from two weeks to a month, then you can increase to 0.05 g for six to eight weeks. If necessary, the dosage is increased to 0.075 g.

Children's daily dosage is calculated at the beginning of 0.5 mg per 1 kg of weight, if necessary, it can be increased for a short period of up to 1 mg per 1 kg of weight, while a single infant dosage should not exceed 35 mg, the supporting dosage is as low as possible.

Signs of excess dose - the appearance of dizziness, headache, requiring the abolition of Neotigazone.

Do not use in combination with tetracycline antibiotics, methotrexate, phenytoin, retinol and its derivatives. Medicines containing alcohol, alcoholic drinks contribute to the formation of tigazone.

When using Neotigazon prescribed to comply with a number of measures: monitoring the functioning of the liver, in diabetics - glycemia, in patients of child age - control indicators of growth and development of the skeleton. Women of childbearing age must necessarily use contraceptives during therapy with the drug, and also during the next two years. Breastfeeding, if necessary, is discontinued.

Store no more than three years, observing the temperature regime up to 25 ° C, low humidity and lack of light.

Methotrexate

In severe forms of psoriasis, when other medicines are ineffective, a cytotoxic methotrexate (antimetabolite vitamin B9) is prescribed. It inhibits cell division and proliferation of tissues, including cancer tumors.

It is available in tablet form for 2.5 mg, 50 units per pack.

The use of the drug by pregnant and lactating women is categorically contraindicated, since it is teratogenic (its use leads to the death of the embryo or congenital pathologies). If the patient becomes pregnant during the treatment period, the question of termination of pregnancy is raised.

Contraindicated also in patients with pathologies of the bone marrow, liver, kidneys.

Methotrexate causes many side effects, both of a general nature and of all organs and systems, including skin defects. It can only be used for the intended purpose and under the supervision of a doctor.

Methotrexate is administered at a dosage of 0.01-0.25 g per week. The increase in dosage occurs gradually, reaching a therapeutic effect, it is reduced, stopping at the minimum effective dosage.

Characteristic signs of an overdose of methotrexate are not revealed, it is determined by the concentration of the drug in the blood serum. Antidote - folinate calcium, is injected immediately after the detection of increased concentrations and conduct other measures that accelerate the removal of the drug from the body.

Like all cytotoxic drugs, methotrexate has a long list of interactions with other drugs, which is in the instructions attached to it. In particular, it is dangerous to combine it with NSAIDs, antibiotics of penicillin, tetracycline, retinoids because of the development of severe intoxication, which can lead to death.

Keep no more than three years, observing the temperature regime up to 25 ° C, in the place inaccessible to sunlight. Keep away from children.

Laminin

Bioactive additive Laminin, which causes the body at the cellular level to independently repair damaged functions, and therefore, according to the manufacturers, completely renew the body and make it healthy. A kind of magic pill that itself solves both the patient and the doctor, what to treat and restore. The main ingredients of Laminin are the extract of a nine-day fertilized chicken egg, yellow pea proteins and cartilage of deep-sea shark. He is positioned as a nutrition corrector, absolutely safe and useful to everyone - and children with half a year, and pregnant women, and nursing mothers. And most importantly, both sick and healthy! Has no side effects, in short, it is used without restrictions. However, the manufacturer recognizes that the body can meet with sensitization to the drug.

Dosing and Administration: from 12 years, daily dose - from one to four capsules. People with serious pathologies should start taking one capsule a day, gradually increasing the dosage to two or three capsules twice a day.

Children under 12 years of age are reduced by half. Babies can open the capsule and mix the contents with water. At reception Lamininum it is necessary to drink not less than two liters of water per day, thus tea, coffee, juice, liquid dishes is not considered.

For more effective action, before using laminin, it is recommended to undergo a course of cleansing the intestine, the easiest way is to use flax seed: dilute a tablespoon of flax seed in a coffee grinder in water and drink in the morning (half an hour before breakfast) and before going to bed.

Folic acid

The cause of the disease is sometimes called deficiency of Folic acid (vitamin B9). The course of this vitamin allows long-term remission. The appointment is made by a doctor.

It is produced in tablet form in 1 mg, 10 and 30 units.

Without the participation of folic acid, oxidative-reduction reactions do not occur in the body. With her participation, the functions of the liver, intestines, hematopoiesis processes are regulated, immunity is strengthened. Admission of folic acid during pregnancy reduces the risk of intrauterine pathologies.

When taken orally absorbed in the organs of the digestive tract completely, in the blood almost all the received dose can be determined in less than six hours. Metabolised in the liver, half the amount taken is excreted by the kidneys, half by the intestine.

With the preventive purpose it is shown to pregnant women, it is possible to appoint or nominate during a lactemia.

Contraindicated with the sensitization of the body to vitamin B9, children under three years.

Occasionally there is a chance of side effects in the form of allergies.

Eat orally after eating one or two tablets from one to three times a day (no more than five pieces).

For children from the age of three, the maximum daily dose is two tablets.

The duration of the course of therapy is not more than a month.

Interaction with other drugs:

• combination of folic acid with tetracycline antibiotics, polymyxin, neomycin, chloramphenicol reduces its absorption in the intestine;
• combination of folic acid with PASK-sodium salt, phenytoin, primidon, sulfosalazine, chlorphenicol, hormonal birth control pills reduces their effectiveness. There is no information about an overdose.

Store no more than three years, observing the temperature regime of 15-25 ° C, low humidity and protection from sunlight.

[8], [9], [10], [11], [12]

Lecithin

Often in the treatment of dermatoses in the drug complex, Lecithin is prescribed, which can significantly weaken the manifestations of the disease. In the human body, lecithin mainly consists of cell walls, so such a food additive is needed as the main building material for the restoration of damaged cells. Lecithin transports nutrients and vitamin components into cells, enhances the effect of medications, binds free radicals, and prevents tissue oxidation.

A person with chronic lecithin deficiency loses the ability to recover and renew, besides, no drugs will help him, until this deficit is filled up.

Issued in capsules of 1.705 g, consisting of 98.6% of lecithin, 0.8% - of monoglycerides, the rest - moisture.

The use of lecithin during pregnancy and lactation is permitted and even welcomed.

Contraindication is the sensitization of the body to lecithin.

It is taken orally during meals two to three capsules per day, with severe forms of psoriasis, an increased dose is required (appointed by a doctor).

Store no more than three years, observing the temperature regime up to 25 ° C, in a room protected from moisture and sunlight.

Milgamma

A prolonged course of psoriasis and frequent exacerbations cause pathological changes in the nervous system of patients. In the complex therapy of such patients, Milgamma is used to compensate for the deficiency of B vitamins, which stabilize the functioning of the nervous system and hemopoiesis.

Tablets for oral administration contain benfotiamine (a lipophilic derivative of vitamin B1) - 0.1 g, pyridoxine hydrochloride - 0.1 g. These vitamins are phosphorylated in the tissues of the body, turning into bioactive components, and take part in many vital physiological processes of tissue metabolism. Metabolites of benfotiamine take part in the carbohydrate metabolism (thiamine triphosphate) and the transportation of aldehyde groups, in the direct oxidation of carbohydrates (thiaminpyruvate). Metabolites pyridoxine participate in the metabolism of the vast majority of amino acids with the formation of hormones (adrenaline, tyramine, dopamine, histamine, serotonin), as well as in the process of hemoglobin synthesis.

Thiamine half-life is 35 minutes, it is not cumulated in tissues, excreted by the kidneys.

The second component of the tablet, converted to pyridoxal-5-phosphate, binds to albumin in the serum, where its hydrolysis occurs, then probably its accumulation in cells.

The use of pregnant and lactating women is not recommended, since the effect of this drug on the fetus and the probability of getting into breast milk has not been investigated.

Contraindicated in violations of heart function, allergies to ingredients, children and adolescents 0-15 years.

Undesirable effects of taking: allergies in various manifestations, weakness, slowing heart rate, heart rhythm disorder, dizziness, nausea, convulsions.

Oral ingestion of milgamma up to three tablets per day (three times one at a time), the maintenance dose is one tablet per day. The duration of the course is four weeks.

Thiamine in combination with other vitamins inhibits their activity; in the sulfate solutions, its complete decay occurs; the activity of thiamine is inhibited by penicillin, glucose, mercuric chloride, salts and esters of acetic, carbonic, iodic anhydride, tannic acid, riboflavin, citric iron, metabisulphite, and decreases in combination with copper and alkaline medium.
Pyridoxine is not prescribed together with levodopa and the medicines containing it.

Overdose causes symptoms similar to side effects.

Store no more than five years, observing the temperature regime up to 25 ° C, low humidity and lack of sunlight.

Mummy in tablets

Mumiye in tablets is a biostimulator prescribed for various diseases, preventing the occurrence of gene mutations, an immunostimulant, accelerating the repair processes in the affected organs and tissues.

The drug includes about three dozen micro- and macro elements, about a dozen metal oxides, phosphorus pentoxide, silicon dioxide compounds, many organic substances.

Produced in tablets of 0.2 g (20 units per package).

The use of mummies by pregnant and lactating women is not recommended, although there is no evidence of a negative effect of this drug.

Contraindicated in case of allergy to components. Side effects are not described.

Take orally in the morning (half an hour before breakfast) and in the evening (with a two-hour interval after dinner). The dose is prescribed by the doctor taking into account the weight and age of the patient.

You can appoint in combination with other drugs, with caution - with euphyllin.

Consequences of overdose may be the phenomenon of digestive disorders.

Store no more than five years, observing the low temperature and humidity.

Befungin

Befungin - a natural analgesic, a regulator of metabolic processes. Tones and strengthens the immune system for people with long-term problems.

Extra Beefungin is produced in round tablets, covered with a shell. Contains extracted birch mushroom parasite chagu, pegus (propolis element) and St. John's wort.

Pharmacodynamics is determined by the components of the drug. It provides systemic protective, strengthening and analgesic action, normalizes metabolism and the functioning of the immune system. Normalizes hemopoiesis.

When psoriasis is used to prevent exacerbations.

Pregnant and lactating women are not recommended for taking without medical advice.

Contraindicated in hypersensitivity to the components of Befungin. Side effects are dyspepsia and allergies.

The recommended dose for adults is sublingually one teaspoon of a dragee three times a day. Duration of treatment can be several years.

The use does not cause dependence, so symptomatic treatment can last several years.

Clinical studies of the use of Befungin in childhood have not been conducted, but the manufacturer insists on the possibility of using the drug from one year.

Store no more than three years, observing the temperature regime up to 20 ° C, low humidity and lack of light.

[13], [14]

Tablets from psoriasis dr nona

Of this series of bioactive additives in the complex of drugs for the treatment of psoriasis is recommended taking capsules "Ravsin". It is recommended for those who could not cope with the elimination of skin imperfections by other means. This is the main tool from the dr nona series to combat skin defects.

Contains extracted fish oil, tocopherol acetate, a complex of minerals of the dead sea.

Produced in capsules at 0.7 g.

Contraindicated in pregnant and lactating women, children, with allergies to dietary supplements.

Take one capsule three times a day during meals. Before treatment, it is advisable to consult a doctor.

There is no information about an overdose.

Keep no more than two years, observing the temperature regime up to 25 ° C and low humidity. Keep away from children.

Tablets from itching with psoriasis

During an exacerbation psoriatic plaques are strongly itchy, and this creates serious discomfort during the day, and especially at night, when itching and burning prevent sleep.

Suprastin

In the complex treatment of relapses of this disease, antihistamines are used to relieve the condition. For example, Suprastin, which provides antipruritic and easy hypnotics.

Produced in tablets of 0.025 g, sealed in blisters of 10 and 20 units, or put up in plastic jars of 20 units.

This drug has classical pharmacodynamics of a representative of this pharmacological group. It blocks the reactions of organs and tissues to histamine, in addition, it acts depressingly on the central nervous system, has a mild hypnotic effect. The active substance is chloropyramine hydrochloride (a blocker of histamine H1 receptors), which has the ability to cleanse the urge to vomit, relieve spasms and soothe the nervous system. Its effectiveness is affected within half an hour after oral administration. The maximum relief comes in an hour and lasts from three to six hours.

Pharmacokinetics: when taken orally, the dose of suprastin taken is almost completely absorbed from the gastrointestinal tract and distributed in organs and tissues, including in the nerves. Metabolism occurs in the liver, excreted in the urine. In childhood, metabolism and elimination is faster.

It is not prescribed for pregnant and lactating women, as well as for paroxysms of bronchial asthma, sensitization to Suprastin and newborns. Exercise caution in appointing patients with prostate adenoma and urinary retention, with closed-angle glaucoma, hepatic and renal insufficiency, cardiac and vascular pathologies, and advanced age.

Unwanted effects as a result of taking the drug almost do not arise and disappear when the reception is stopped.

Symptoms of a nervous breakdown (weakness, drowsiness, dizziness, nervous excitement, tremor, headache, euphoria), dyspeptic disorders; hypotension, tachycardia, heart rate disorders; difficulty urinating; intraocular hypertension, photosensitivity, extremely rare - disorders of hemopoiesis.

During the reception, do not perform work that requires concentration.

Take orally during meals, drink water at least a glass.

Children from a month old to one year are given a quarterly tablet twice or thrice a day, rubbing it into powder; 1-5 years - a quarter of a tablet three times or half a tablet twice a day; 6-13 years - half a tablet twice or thrice a day; from 14 years - one tablet three times-four times a day.

Overdose causes hallucinatory disorders, overexcitation, akinesia, convulsions and post-convulsive depression, coma; in young children - anxiety, dry mouth, stopped dilated pupils, flushing, sinus tachycardia, difficulty urinating, fever, coma.

First aid - enterosorbents, gastric lavage.

Appointing Suprastin in combination with sedative, analgesics, tranquilizers and antidepressants, atropine, sympatholytic drugs, one must take into account the mutual enhancement of the action of the drugs.

Store no more than five years, observing a temperature regime of 15-25 ° C. Keep away from children.

Tavegil

A similar effect has Tavegil, which is produced in tablets of 1 mg (20 units per package). A classic antihistamine drug that does not cause a hypnotic effect.

Has a longer antiallergic activity than Suprastin, approximately 12 hours (sometimes - a day).

It is not prescribed to pregnant and lactating women, children under six years of age.

Has similar contraindications and side effects.

Apply orally before eating, drink plenty of water.

Children from six to 12 years are prescribed half or whole pill twice a day; After reaching the age of 12 take one tablet twice a day.

At heavy degrees, the daily dose is increased, but no more than up to 6 mg.

Overdosing leads to depression or stimulation of the nervous system, dry mouth, dilated pupils, flushing of the head, dyspeptic disorders can be observed.

In combination with hypnotics, sedatives, tranquilizers, m-holinoblokatorami, as well as alcoholic beverages, there is a mutual enhancement of the effect of these drugs.

During the treatment period, one should refrain from work requiring increased concentration of attention.

Store no more than five years, observing the temperature regime of 15-30 ° C. Keep away from children.

Cetrin

More modern antihistamine drug prolonged action Cetrin.

It is produced in tablets of 0,01 g, in blister - 20 units.

The active component is cetirizine blocking the H1-histamine receptors. Reduces the manifestations of allergies and has a preventive effect, as well as reduces the manifestations of exudation and itching, blocks the release of inflammatory activation factors at later stages and the appearance of a histamine-mediated early stage of an allergic reaction. Has no sedative effect.

The effect of taking is achieved in half of the patients after a third of an hour, in the rest - after an hour and lasts 24 hours. It is not addictive, after the cessation of the effect, the effect remains for 72 hours.

The highest concentration is observed in the blood serum one hour after absorption from the gastroduodenal tract, it decreases by 23% if Tetrin is received during meals.

Metabolized in the liver, does not accumulate in tissues and organs, is excreted in adults after seven to ten hours, in children - after six. The main part is excreted by the kidneys (2/3), the intestine - 10%. In elderly people, the half-life period is 1.5 times longer.

The use of pregnant and lactating women is contraindicated, and is not prescribed for children 0-5 years old and when sensitized to cetirizine and hydroxyzine.

Side effects are typical for drugs of this pharmacological group.

Take orally with water. Children 6-12 years - half a pill twice a day, people over 12 years - one tablet during the day. The course of admission: from one week to a month, if necessary - up to six months.

It is undesirable to interact with sedatives and theophylline.

Exceeding the recommended dose causes drowsiness, tremor, increased heart rate, rash, delay in urination, itching. First aid is gastric lavage, provocation of vomiting, enterosorbents and laxatives.

Store no more than two years, observing the temperature regime up to 25 ° C, in a dark place. Keep away from children.

[15]

Hormonal pills against psoriasis

The classical scheme of treatment of psoriasis suggests to begin therapy with the most harmless preparations, for example, prednisolone, and only in case of lack of efficiency to appoint more powerful.

However, American dermatologists practice a different tactic: at the very beginning of treatment, an effective hormone preparation of the new generation is appointed to remove the main symptoms, while the supporting therapy is carried out with a more moderate drug.

Nevertheless, in each case, strong drugs are used in short courses, as they provoke a number of serious side effects.

Betamethasone

From hormonal tablets in the treatment of psoriasis use a systemic glucocorticoid Betamethasone or its analogs. It is used in severe forms of psoriasis, in particular, psriatic arthritis.

Produced in tablets of 0.5 mg Betamethasone, packed in 30, 100 or 500 units.

Has a powerful effect, directed against proinflammatory and proallergic factors in all phases of the process, quickly eliminates burning and itching.

Strengthens cell membranes, including - lysosomes, which leads to a decrease in their density in the inflammation zone, suppresses the movement of neutrophils and macrophages into this zone, as well as their phagocytic activity. Normalizes microcirculation, strengthens the walls and narrows the lumen of blood vessels, reduces the phenomenon of exudation.

It inhibits the proliferation of tissues, reducing the number of B- and T-lymphocytes, mast cells, as well as the formation of antibodies, the sensitization of effector cells to proallergic mediators. Suppresses immunity, reducing the activity of B- and T-lymphocytes and interfering with the release of interleukins from leukocytes and macrophages.

Influences metabolic processes: accelerates the production of glucose in the liver, protein catabolism, fat redistribution, delays sodium and water, promotes the excretion of potassium and calcium.

Pharmacokinetics: has good absorbent properties - with oral administration, the highest concentration is achieved after one to two hours.

It joins with blood proteins. Well overcomes the histohematological barriers (placental - including), is found in breast milk. Metabolized by the liver, forming inactive metabolites. Eliminated by the kidneys.

The use of hormonal tablets by pregnant and lactating women is not recommended.

Contraindicated in patients with arterial hypertension, diabetes, severe circulatory disorders, open tuberculosis, ulcerative lesions of the gastroduodenal tract, syphilis, hypocalcemia, mental pathologies, glaucoma, generalized fungal infections.

Side effects: weight gain, hypocalcemia, fractures of long bones, hypertension, puffiness, peptic ulcer of the gastrointestinal tract, relapses of slow infectious processes, increased blood sugar, irritability, insomnia, disorder of menstruation cycle, dysfunction of the adrenal cortex.

The method of use, dosing and treatment regimen is prescribed by the doctor, guided by anamnesis and the patient's response to therapy. When the therapeutic effect is achieved, the dosage is gradually reduced by 0.025-0.05 g every three days to the supporting one.

The drug is recommended to take in the morning, which corresponds to the natural biorhythm of the release of the hormone.

Interaction with phenobarbital, diphenin, rifampicin, ephedrine accelerates the decomposition of Betamethasone, reducing its effectiveness.

Preparations containing estrogens greatly increase its effectiveness.

Combination with diuretics reduces the potassium content in the blood.

The combination with digitoxin increases the toxicity of the latter, and with cardiac glycosides - increases the risk of a breakdown in the rhythm of contractions of the heart.

Store no more than three years, observing the temperature regime up to 25 ° C.

[16], [17], [18], [19]

Tablets cleansing the liver for psoriasis

In the complex treatment of psoriasis, especially complicated forms, hepatoprotectors are used, which purify and restore liver cells.

Heptral

It is available in tablet form for 0.4 g 10 or 20 units per package.

The active substance ademetionine is a natural component of the tissues and physiological fluids of the human body, a hepatoprotector possessing antidepressant qualities. It increases the production and facilitates the escape of bile, removes intoxication, restores liver cells, binds free radicals, prevents fibrosis. Reducing the level of ademetionine causes an oppressed, depressed mood. Heptral not only compensates for the deficiency of this substance, but also boosts its synthesis in the liver, brain and spinal cord and other organs. Its use is accompanied by a positive dynamics of liver function tests.

The normal secretion of bile and the functioning of the liver cells after the drug has been withdrawn remain for another three months.

Ademethionine, getting into the body with the drug, undergoes a transformation similar to a natural substance. With an increase in its level, methylation of phospholipids in the envelopes of neurons is normalized, thereby prolonging their life span and stabilizing the transfer of nerve impulses.

The antidepressant effect is formed quickly, the maximum is observed at the end of the week of admission.

Use of tablets Heptral by pregnant and lactating women is not recommended. If necessary (if the probable benefit brought to a woman exceeds the danger for her unborn child), the medicine may be applied for 7-9 months. For the appointment of nursing mothers, the possibility of transferring a child to artificial feeding is considered.

Contraindicated in case of sensitization to ingredients.

Side effects: allergies, dyspepsia, sleep disorders.

Dosing and Administration - inside of two to four tablets in the interval breakfast → lunch, as the drug has a mild stimulating effect. Wash down with water, do not grind. The average duration of the course of treatment is two to eight weeks.
Excess dose is not known.

Keep no more than three years, observing the temperature regime up to 25 ° C.

Phosphogliv

Produced in capsules of 0.1 g, of which phospholipids - 0.065 g, glycyrrhizinate sodium - 0.035 g.

A complex drug that stabilizes cell membranes and protects liver cells from damage, including viruses. Active substances: phospholipids, in which the cytoprotector phosphatidylcholine and antiviral agent - glycyrrhizic acid.

Phosphatidylcholine, a natural element of the liver cells, restores damaged structures of the cell membranes, with its help, there is a regulation of the metabolism of proteins and lipids. Phospholipids prevent liver cells from losing enzymatic and other components, activate the ability of the liver to excrete toxins, and also prevent the proliferation of connective tissue (fibrosis and cirrhosis) of the liver.

Glycyrrhizic acid is an active antagonist of viruses and inflammations. Prevents the reproduction of viruses, stimulating the production of interferons, increasing the activity of natural phagocytes. Acid strengthens the walls of the liver cells and binds free radicals. Increasing the activity of endogenous corticosteroids, prevents the development of inflammation and allergic reactions.

With psoriasis, this drug prevents the appearance and spread of plaques due to the stabilization of cell membranes and metabolic processes, the suppression of proinflammatory factors and the removal of intoxication.

The phophogliva active ingredients ingested are well absorbed into the digestive tract, binding in blood to the protein and lipoprotein components of the plasma. Phospholipids obtained with the drug, combined with endogenous for several hours from the time of admission, the therapeutic concentration of glycyrrhizic acid circulates in the tissues of the body for about half a day. Elimination of it occurs with bile.

The use of Phosphogliva in pregnant and lactating women is not recommended, since the effect on the embryo and breast milk has not been studied.
Contraindicated in patients with established allergies to constituent agents, children 0-12 years old, persons with hypertension in the vein of the portal vein.

As a result of the use of the drug in some cases, the following side effects may develop:

• allergic reactions;
• arterial hypertension;
• swelling.

Dosage and administration: during the meal, swallow whole, with water, it is recommended to take one or two capsules in three to four doses per day. Duration of admission varies from a month to six months, the schedule of admission is determined by the doctor.

In combination with GCS, the likelihood of increasing their effects and side effects increases.

Information on the consequences of exceeding the dose of the drug has not been published.

Keep no more than three years, observing the temperature regime of 15-20ºС.

Essentiale forte

Available in capsules 0.3g, packed in 30 or 100 units.

The active ingredient is essential phospholipids (a fraction of high purification phosphatidylcholine), structurally similar to endogenous, but superior in content to polyunsaturated fatty acids, in particular, linoleic. Phospholipids, which are a natural component of liver cells, are directly involved in the processes of cellular reproduction. They regulate the permeability of membranes of hepatocytes, intracellular respiration, biooxidation, metabolism. With toxic lesions of the liver, the production of endogenous phospholipids and, consequently, their functions are violated.

The action of Essentiale is aimed at the elimination of violations of the integrity of cells and their membranes, restoration and normalization of liver function. Use of pregnant and lactating women is only possible by appointment of a specialist.

Contraindicated with known sensitization to the components of the drug.

Very rarely, as a side effect, diarrhea is observed.

The approximate scheme of therapy for psoriasis: the initial dosage is two capsules three times a day for two weeks, then ten intravenous injections in combination with PUVA-therapy, then again oral intake of the course in two months.

Interaction with other drugs was not revealed, the consequences of exceeding the dose were not reported.

Store no more than three years, observing the temperature regime up to 25 ° C, in rooms with low humidity. Keep away from children.

[20], [21], [22]

Karsil

Produced in pellets of 0.03 g, packed in 80 units.

The active ingredient is silymarin (extract of milk thistle). Silymarin is a stabilizer of cell membranes that reduces toxins' exposure to liver cells and stimulates their renewal. It has the ability to bind free radicals and normalizes metabolic processes in hepatocytes.

Reception Karsila has a positive therapeutic effect, which affects both the patient's well-being and the normalization of laboratory tests. Eliminated mainly by the kidneys.

Use of pregnant and lactating women - for strict medical reasons.

Contraindicated in cases of allergies to Karsila ingredients, children 0-5 years.

Side effects: dyspeptic manifestations, it is extremely rare - hair loss and vestibular apparatus disorders, passing by themselves after the end of the admission.

The treatment regimen is determined by a doctor, the recommended dosage is not more than four pills three times a day, the duration of therapy is not less than three months.
Children's daily dosage is calculated in this way - 5 mg / kg of weight, divided into three doses.

Interaction with other drugs was not revealed, the consequences of overdose were not reported.

Store no more than three years, observing the temperature regime of 16-25 ° C, with low humidity and no light. Keep away from children.

Psoriasis is one of the most famous and very common, and at the same time - mysterious diseases. The reasons for it still remain in the field of assumptions and manifestations are very individual. Relapses of vulgar psoriasis without complications are treated, mainly, by local medications. In this case, the so-called "ladder of therapeutic measures" is used, along which steps from the simple means of local application to the increasingly strong. If external means are ineffective, when 2/3 of the stairs are passed, only then tablets are prescribed. The strongest of them are immunosuppressors, very effective, but very toxic.

Tablets from psoriasis of a new generation appeared at the beginning of the XXI century. They have the ability to selectively inhibit the activity of T-lymphocytes (alefacept, ustekinumab, adalimumab, infliximab). These drugs are highly effective, however, against the background of a decrease in the immune barrier, the probability of secondary infection is high. Moreover, their pharmacological properties have not been sufficiently investigated.

To top it all out, effective psoriasis tablets can only be found in the treatment of a particular patient under the supervision of a dermatologist.