Tablets from the fungus of nails

In pharmacology a large assortment of tablets from the fungus of nails. They have different degrees of effectiveness, different ways of using and influencing the pathogen. All used tablets are more or less toxic to the liver and their effectiveness against nail fungus is much lower than that of topical preparations (cream, drops, ointment, lacquer).

Before you start fighting with a nail fungus, you need to have an idea of what the disease is and how dangerous it is. The manifestation of this unpleasant disease depends on the depth and extent of the lesion. Many problems are caused by the fungus, which settled on the skin of the feet and nails of the legs.

The first signs of the disease can be cracks in the legs, skin peeling, itching, and later and yellowing and brittle nails. This is a consequence of the fact that it flexibly affects the nail plate, thereby making it more fragile and yellow. Such signs not only do not look aesthetically pleasing, but also cause a lot of problems. Over time, if you do not treat this disease, the mycelial fungus extends to the nail plate not only on the legs, but also on the hands. Also fungal and internal organs can be affected, which is extremely rare.

Today, there are many medications that can help in the fight against the fungus of the nail, but self-medication is not recommended, as this may not improve, but exacerbate the situation. First of all, with the slightest inconvenience, you need to turn to the dermatologist, hand over all the necessary tests and then get a comprehensive treatment that will give positive dynamics.

All drugs for the treatment of nail fungus can be divided into internal and external means:

1. Internal - tablets from the nail fungus, which are prescribed to patients with weakened immunity, diabetes, people over 50, in the case of very rapid fungus development or with a very large lesion area. The effect of the oral drug should be combined with topical agents, for example creams or ointments.
2. External application is a cream, drops, a varnish, ointment. Lacquer and drops are applied directly to the nail, and creams and ointments are more convenient and effective for treating the fungus on the feet.

Indications for the use of tablets from nail fungus

Indications for the appointment of tablets from the fungus of nails are mycosis of the nails of the hands or feet in combination with fungal lesions of organs, fungal lesions with complications.

Tablets must be taken before complete remission.

Pharmacodynamics and pharmacokinetics

Tablets from the nail fungus, getting into the body are absorbed in the gastrointestinal tract and active substances with blood are carried throughout the body, which causes the cessation of further reproduction of the fungus.

Advantage of tablets is that they are able to cure completely not only the nail fungus, but also mycoses of other localizations, because they contain components that destroy the walls of fungal spores, thereby destroying the fungus.

Pharmacodynamics drugs from the fungus of nails is to destroy the walls of spores of the fungus and block the synthesis of fungal sterols. It has a fungicidal effect on dermatophytes, some pre-morphous fungi and their forms, mold fungi. Depending on the type of fungus the drug has a fungicidal or fungistatic effect.

After taking the medicine is well absorbed from the digestive tract and quickly penetrates into the dermal layer of the skin and the nail plate. The drug can penetrate the secret of the sebaceous glands, accumulate in the hair follicles, hair, subcutaneous tissue. The substances are biotransformed in the liver with the formation of inactive metabolites and are excreted in the urine (about 80%), and feces (20%). The age of patients does not affect the pharmacokinetics of drugs, the excretion in liver or kidney lesions can only decrease.

Terbinafine

Antifungal agent for systemic use. It is active against diseases caused by pathogens Trichophyton, Microsporum canis, Epidermophyton floccosum.

Contraindications to the use of terbinafine tablets are limited by hyper-responsiveness to the drug.

Terbinafine is very well tolerated, and adverse reactions are not pronounced and are of a rapid nature.

According to the instructions, Terbinafine tablets are administered 1 tablet per day. The duration of treatment depends on the nature of the disease and the severity of the course.

Packing: 250 mg tablet number 10 in the blister pack.

Shelf life of the drug is 3 years.

Irunin

Synthetic antimycotic systemic use. Has an effective effect in the treatment of fungus, not only nails and skin, but also internal organs.

Irunin is contraindicated in people with hypersensitivity to Itroconazole, in the first trimester of pregnancy. Do not recommend combining with simvastatin, lovastatin, triazole, cisapride.

When fungal diseases Irunin used for 1 tablet a day for 15 days.

Shelf life - 2 years.

Fluconazole

Antifungal preparation of systemic use.

Indication: cryptococcosis, treatment of HIV carriers and AIDS patients, patients after organ transplantation and receiving immunosuppresant therapy. Also, fluconazole is used to treat candidiasis, dermatomycosis and endemic mycoses.

Do not recommend the use of the drug with increased sensitivity to fluconazole or azole compounds, the simultaneous use of terfenadine, cisapride, pregnancy and lactation.

The daily rate of fluconazole depends on the nature and severity of the infection. The recommended dose for a nail fungus is 150 mg per week (3 tablets per week). Treatment should be carried out until the healthy nail grows, on average, 3-6 months.

Among the side effects may be headache, diarrhea, nausea, sometimes vomiting.

In case of overdosage, gastric lavage is recommended.

The use of nail fungus tablets during pregnancy should be avoided, with the exception of fungal infections that threaten the life of the unborn child or mother. During the period of breastfeeding, the drug was found in the same concentrations in milk as in blood.

Children can take fluconazole after 6 years.

Shelf life of the drug is 2 years.

[1], [2], [3], [4], [5]

Orungal

Antifungal agent for systemic use.

It is indicated for use in dermatomycosis, fungal keratitis, vaginal candidiasis, systemic fungal infections.

Orungala capsules are contraindicated in patients with hypersensitivity to the drug or its components, heart failure, pregnancy and lactation.

Take 200 mg (2 tablets) per day Orungala for 7 days.

Adverse reactions: rarely edema, minor indigestion. 

In case of an overdosage, it is necessary to rinse the stomach and drink activated charcoal.

Shelf life - 3 years.

Lamisil

Antifungal drug system use with a wide range of antifungal effects in infections of the skin, hair, nails.

Indication: fungal skin and nail infections caused by Trichophyton, Microsporum canis and Epidermophyton floccosum.

Do not recommend the use of Lamizil to patients with hypersensitivity to the components of the drug.

Adults appoint 1 tablet Lamizila 1 time per day. Duration of use depends on the nature and severity of the disease and can be from 6 weeks to 3 months.

Using tablets from nail fungus Lamisil during pregnancy is not advisable. Also, the components of the drug penetrate into breast milk, so during the feeding the woman should not receive treatment with this drug.

Overdose can cause headache, nausea, dizziness. Treatment in this case is to receive activated charcoal.

Side effects of the drug are mild and rapid.

Shelf life is 3 years.

Lamicon

Antimycotic system use in cases of fungal infection of nails, scalp, skin.

Contraindicated the use of Lamicon for patients with hypersensitivity to terbinafine or other components of the drug.

Duration of treatment with the drug depends on the nature and severity of the course of the disease from 2 to 12 weeks. Lamicon take 1 tablet 250 mg once a day.

Side effects of the drug are insignificant and not particularly noticeable for the patient.

Overdose can cause headache, nausea, vomiting, dizziness. If one of the above symptoms appears, you must rinse the stomach and take activated charcoal.

During pregnancy and lactation, it is not recommended to take Lamicon.

Shelf life 2 years.

Exifin

Antifungal systemic drug for the treatment of skin, hair, nail infections caused by Trichophyton, Microsporum, Candida, Pityrosporum.

Do not recommend the use of Exifin in patients with hypersensitivity to the components of the drug.

Adults are recommended to take 1 tablet 250 mg once a day. Treatment lasts from 2-6 weeks to 3 months.

When an overdose occurs headache, nausea, dizziness. In this case, it is necessary to take activated charcoal.

Among the side effects are often a decrease in appetite, headache, a violation of taste, nausea.

When pregnancy is not recommended.

Shelf life of the drug is 3 years.

[6], [7]

Pimafucine

Antibacterial and fungicidal preparation of a wide spectrum of action is sensitive to fungi of the genus Candida albicans.

Adults are recommended to take 1 tablet 4 times a day for 2-3 months, supplementing the treatment with topical application of Pimafucin cream for better effect.

The drug can be used during pregnancy and during lactation.

The drug Pimafucin contains lactose, therefore it is not recommended for patients with a rare congenital intolerance to this substance. Also, you should carefully take the drug to people with diabetes.

There is no information about an overdose.

Among the side effects observed nausea, diarrhea, which occur in the first days of use and independently pass during treatment.

Shelf life of the drug is 4 years.

Furacilin

Antiseptic and disinfectant preparation for solution.

Contraindications: hypersensitivity to the components of the drug.

Applied for the treatment of anaerobic infections and inflammatory processes.

Furacilin is used in the form of an aqueous solution. For its preparation, 1 tablet is diluted in 100 ml of fiz. A solution of either distilled water. Take 15-minute baths of this solution with the affected parts (arms, legs).

Side effects of the drug can manifest itself in the form of allergic reactions on the skin, which, after discontinuing the use of the drug pass.

Overdose is expressed in increasing the intensity of adverse reactions.

Shelf life 5 years.

In order not to catch a nail fungus, you need to take care of your immunity. Because with a strong immune system, infection is less possible. If the body is weakened, the fungus spreads very quickly and it is not easy to fight with it. In order not to fall into the risk group of infection with a fungus, it is enough to observe several rules:

• Bath, sauna, swimming pool - in these rooms it is necessary to wear closed rubber shoes;
• Wear socks only from natural materials, not synthetics and change them daily;
• It is not advisable to wear someone else's shoes;
• After water procedures, wipe your feet well and make sure that they are always dry when possible.