Tablets from abdominal pain

Pain in the abdomen can have a different origin. Therefore, the means that help to cope with this disease differ in their characteristics. Tablets from abdominal pain are designed to treat any one problem or complex of related symptoms.

Cutting pains in the navel can indicate problems with the stomach or gastritis.

On the right, in the hypochondrium can be ill gallbladder because of the presence of stones in it, or to let the liver know about oneself. The pain on the left, under the ribs, indicates the dysfunction of the pancreas, and below in the same area - on problems with the duodenum. Pain in the abdomen with indeterminate localization and the presence of indigestion signs can mean problems with the intestines. A pain sensation of a spasmodic nature is caused by spasms of the pelvic area musculature. Such pain occurs in women during menstruation. Each of these problems requires its own way of treatment, and accordingly, the use of certain drugs.

Of course, it is important to understand that abdominal pain can be a manifestation of a serious disease, dangerous to human life, for example, acute appendicitis. In this case, the pain sensations are localized on the lower right. In pregnant women, pain in the abdomen may indicate the presence of an ectopic pregnancy, which is dangerous for her life. Therefore, self-medication is not worth it, but it is best to seek advice and help from specialists.

Indications for the use of tablets against abdominal pain

Each drug is intended for use in certain cases. Indications for the use of pellets from abdominal pain are printed in the instructions that provide the medication, and these indications must be read before starting the use of the medication.

1. Drotaverina hydrochloride.
   • Presence of spasms of smooth muscles related to the biliary tract, which are caused by cholestolithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis and papillitis.
   • Symptoms of smooth muscle cramps, which is present in the urinary tract, and caused by nephrolithiasis, urethrolithiasis, pyelitis, cystitis, bladder thesis.
   • Used as a means of auxiliary therapy for spasmodic manifestations in the smooth muscles of the stomach and intestines caused by peptic ulcer of the stomach and duodenum, gastritis, cardia and pyloric spasms, enteritis, colitis, spastic colitis with constipation and meteoric forms of mucous colitis.
2. Duspatalin.
   • Used for spasms of the gastrointestinal tract, which can also be caused by organic diseases.
   • It is used for intestinal and biliary colic.
   • Used for irritable bowel syndrome.
   • For children from the age of twelve years, the medication is used for functional disorders of the gastrointestinal tract, which are accompanied by pain in the abdomen.
3. Imodium Plus.
   • The occurrence of diarrhea with any cause of origin.
   • The appearance of concomitant symptoms - flatulence, non-intestinal gas, abdominal discomfort, spastic pain.
4. Loperamide.
   • The appearance of acute and chronic signs of diarrhea, which has allergic, emotional, medicinal or radiation origin.
   • It is used in the treatment of diarrhea associated with changes in the regimen and quality of nutrition, with disturbed metabolism and absorption processes.
   • Used as an aid in the treatment of diarrhea, which is of an infectious nature.
   • It is used to regulate stool in patients with igestom.
5. Maalox.
   • Presence of exacerbation of peptic ulcer of the stomach and duodenum.
   • The appearance of exacerbation of acute gastroduodenitis and chronic gastroduodenitis, which have a normal or increased secretory function.
   • The appearance of a hernia, which has a diaphragm in the esophagus, and the appearance of reflux esophagitis.
   • The presence of dyspeptic phenomena in the form of discomfort or pain in the epigastrium; the appearance of heartburn, acidic eructations after eating disorders, as well as excessive consumption of alcohol, coffee drinks and smoking.
   • The emergence of dyspeptic phenomena in the form of discomfort and epigastric pains, as well as symptoms of heartburn, acidic eructations, which can arise as a result of the use of certain medicines - nonsteroidal anti-inflammatory drugs and glucocorticosteroids.
6. Mezim Forte.
   • It is used in substitution therapy, which treats the insufficiency of the exocrine function of the pancreas, including chronic pancreatitis, cystic fibrosis.
   • It is prescribed for chronic inflammatory-dystrophic gastric, intestinal, hepatic diseases, and similar problems with the gall bladder.
   • These pills for abdominal pain are used in disorders of the gastrointestinal tract, which are of a functional nature and are caused by intestinal diseases of an infectious nature and irritable bowel syndrome.
   • With errors in nutrition in patients with normal functioning of the gastrointestinal tract.
   • Used as a therapy of conditions that caused resection or irradiation of the gastrointestinal tract: digestive disorders of food, flatulence, diarrhea.
7. But-shpa Forte.
   • Used for spasms of smooth muscles, caused by diseases of the biliary tract, namely cholecystolithiasis, hollyiolithiasis, cholecystitis, pericholecystitis, holangi, papillitis.
   • It is used for spasms of the smooth muscles of the urinary tract caused by certain diseases, namely, nephrolithiasis, urethrolithiasis, pyelitis, cystitis, and bladder spasms.
   • As an element of auxiliary therapy is taken with spasms of smooth muscles of the gastrointestinal tract caused by peptic ulcer of the stomach and duodenum, gastritis, cardia and pyloric spasms, enteritis, colitis, spastic colitis with accompanying constipation and irritable bowel syndrome with manifestation of flatulence. The medication must be taken in these cases if the diseases characterizing the syndrome of the acute abdomen, namely, the signs of acute appendicitis, peritonitis, perforation of the ulcer, acute pancreatitis are excluded.
   • Used for headaches caused by stress.
   • It is used for dysmenorrhea accompanying painful sensations.
8. Festal.
   • The presence of inadequate secretion in the pancreas that accompanies chronic pancreatitis and is combined with biliary insufficiency, which is manifested in the disturbed digestion of food, flatulence, constipation.
   • Used as one of the means for combined treatment, diseases such as diffuse hepatic diseases associated with alcoholic and toxic liver damage, liver cirrhosis.
   • It is used as part of complex therapy for the loss of bile acids in large quantities, usually in patients who have undergone cholecystectomy.
   • It is used as one of the medicines for combined treatment with disrupted circulation of bile acids, which is observed in diseases such as biliary dyskinesia, dysbacteriosis, malabsorption.
   • It is used for neurohumoral disorders of the function of the processes of bile formation and its separation, which accompany chronic diseases of the gastrointestinal tract, namely chronic gastritis, chronic duodenitis, chronic cholecystitis.
   • Used to improve the processes of digestion of food in those patients who differ in the normal functioning of the gastrointestinal tract. This can happen if there is a violation of proper nutrition, as well as problems with chewing function, prolonged immobilization, sedentary lifestyle.
   • Appointed in preparation for the examination of the internal organs of the peritoneum by X-ray and ultrasound diagnosis.
9. Phthalazole.
   • The emergence of dysentery in acute form or exacerbation of the chronic form of the disease.
   • The appearance of colitis.
   • The occurrence of gastroenteritis.
   • The need for preventive measures against the occurrence of purulent complications after surgical operations in the intestine.

Form of issue

Tablets for oral use - this is the form of release of the drugs described in the article. They differ in color, size, shape and smell, have or do not have a shell.

• Drotaverina hydrochloride.

It is produced in tablets of forty milligrams of the active ingredient in each. Tablets have a yellow or yellow with a greenish tinge color, a flat-cylindrical shape and a chamfer in the middle. Tablets are placed in a contour squamous package of ten pieces each and are packaged in carton packs of two contour packs, and also supplied with a leaflet with instructions.

Drotaverin Forte contains in each tablet eighty milligrams of active substance and is available in tablets. Tablets are placed in a blister for ten pieces, two blisters are packaged in a cardboard box and supplied with an insert instruction.

Each tablet contains forty grams (or eighty grams) of drotaverine hydrochloride, as well as a number of excipients: lactose monohydrate, potato starch, talc, stearic acid.

• Duspatalin.

It is produced in capsules with prolonged action, which is white and marked on the body in the form of 245 digits, and on the cap of the capsule - Latin letter S and number 7. Capsules are not transparent and made of hard gelatin. Inside the capsules, there are granules of white or almost white color. Capsules are packaged in a blister pack of ten in each. Blisters of two or three pieces are placed in a cardboard box and supplied with a leaflet with instructions.

Each capsule contains two hundred milligrams of active substance - mebeverine hydrochloride, as well as a number of auxiliary substances: magnesium stearate, methacrylic acid copolymer, talcum, hypromellose, methacrylic and ethacrylic acid copolymer, glycerol triacetate, gelatin, titanium dioxide.

• Imodium Plus.

Produced in the form of chewable tablets, which are white and a round flat shape, as well as the IMO inscription on one side of the tablet. They have vanilla and mint flavor.

Each tablet contains active substances loperamide hydrochloride - two milligrams and simethicone - one hundred and twenty five milligrams, as well as a number of auxiliary components: sugar, microcrystalline cellulose, basic polymethacrylate, cellulose acetate, sorbitol, dextrates, vanilla, sodium saccharin, stearic acid, calcium phosphate.

Packed on four or twelve pieces of tablets per package.

• Loperamide.

The medicine is produced in the form of hard gelatin capsules No. 3, which have a white body with a green lid. In capsules is a white or white with a yellow shade of powder. Capsules have a weight of two milligrams. The capsules are placed in ten pieces in a planar cell package. One or two cell packs are placed in a cardboard box and supplied with a liner with instructions.

In one capsule there is an active substance - loperamide hydrochloride - two milligrams, as well as a number of auxiliary components: lactose monohydrate, potato starch, colloidal silica, calcium stearate. The body of the gelatin capsule consists of gelatin and titanium dioxide, and the cap of the capsule has a composition in the form of gelatin, titanium dioxide, iron dye, yellow oxide and indigo carmine.

• Maalox.

Produced in the form of chewable tablets with sugar and chewable tablets without sugar. Chewable tablets with sugar have a white color and a round, flat-cylindrical shape. Also on the tablet there is a chamfer and an engraving "Mx".

Tablets from abdominal pain without chewing sugar have a white or yellowish color with the presence of some marbling, a round and flat-cylindrical shape. The tablets have chamfer and engraving "MAALOX" on one side and on the other - "sans sucre". Tablets differ in lemon scent.

Chewing tablets with sugar are placed ten in a blister produced by their aluminum foil or PVC. One, two or four blisters are placed in a cardboard bundle and supplied with a leaflet with instructions.

Tablets are chewed sugar-free packaged in ten pieces in a blister, made of aluminum foil, PVC or PVDC. One, two or four blisters are placed in a cardboard bundle and accompanied by a leaflet with instructions.

In one tablet with sugar there are four hundred milligrams of active substances - magnesium hydroxide and an alginate, as well as a number of auxiliary components: starch with sucrose, sorbitol, mannitol, magnesium stearate, mint flavor, sodium saccharinate, sucrose.

In tablets without sugar contains four hundred milligrams of active substances - magnesium hydroxide and alglandarate, as well as a number of auxiliary components: sorbitol of liquid, maltitol, magnesium stearate, lemon flavor, flavoring preparations, natural flavorings, gum acacia, citric acid, butylhydricanilazole, sodium saccharinate, glycerol, talc.

• Mezim Forte.

Produced in the form of tablets of pink color and round shape, which covers the enteric coating. Each tablet has a biconvex surface, a facet, as well as its fracture, you can see a little brown inclusions.

The tablets are placed in ten pieces in a contour cell box made of aluminum, polyamide or PVC. One or two blisters are placed in a cardboard bundle and supplied with an insert instruction.

Each tablet has a core and an enteric membrane. The core consists of active substance - pancreatin powder in the amount of one hundred and thirty seven and a half milligrams, in which there is lipase - ten thousand units, amylase - seven and a half thousand units, protease - three hundred seventy five units. Of the auxiliary components, there is some lactose monohydrate, microcrystalline cellulose, colloidal silica, crospovidone, magnesium stearate.

The enteric membrane consists of a certain amount of hypromellose, methacrylic acid, ethyl acrylate copolymer, a dispersion of thirty percent, triethyl citrate, titanium dioxide, talc, simethicone emulsion of thirty percent, macrogol 6000, carmelose sodium, polysorbate 80, azorubin varnish, sodium hydroxide.

• But-shpa Forte.

It is produced in tablets of forty milligrams each. The tablet has a round biconvex shape and yellow color, with some green or orange tinge. On one side of the tablet there is a "spa" engraving.

Tablets are packaged in six or twenty-four pieces in one blister, made of aluminum or PVC. One blister is placed in a cardboard box and is accompanied by an insert instruction.

Also, tablets can be packaged in vials made of polypropylene and equipped with a unit doser, in the amount of sixty pieces per bottle.

Tablets from abdominal pain are also placed in a polypropylene bottle of one hundred pieces in each and are supplied with a polyethylene stopper.

Each bottle is packed in a cardboard box and supplied with a leaflet with instructions.

Each tablet contains an active substance - drotaverina hydrochloride - forty milligrams, as well as a number of auxiliary components: magnesium stearate, talc, corn starch, lactose monohydrate.

• Festal.

The drug is available in the form of white, glossy, round pills, which have a weak vanilla scent. Dragee, ten pieces are placed in strips, and strips are packaged in cardboard packs in the number of two, four, six or ten pieces, supplied with a leaflet with instructions.

One dragee contains one hundred and ninety-two milligrams of pancreatin active substance, fifty milligrams of the active component of hemicellulose and twenty five milligrams of the active substance of the bile component. In addition, the dragee contains a number of auxiliary substances: sodium chloride, cellacephate, ethyl vanillin, castor oil, sucrose, methylparahydroxybenzoate, propylparaben, gelatin, liquid glucose, talc, calcium carbonate, gum acacia, longrope, macrogol, titanium dioxide.

• Phthalazole.

The drug is available in the form of tablets of white or white-yellowish color, have a flat-cylindrical shape and a facet with a risk. Tablets are packaged in ten pieces into a contiguous, non-jellied package or a contiguous cell package. Two contour packs are placed a cardboard box and are supplied with a sheet with instructions.

In one tablet there are five hundred milligrams of active ingredient of phthalylsulfatiazole and a number of auxiliary substances: potato starch, calcium stearate, talc.

[1], [2]

Pharmacodynamics tablets from abdominal pain

The processes occurring in the body after taking the drug are different. Each drug is designed to solve certain problems. The mechanism of action is described in the pharmacodynamics of tablets from abdominal pain.

• Drotaverina hydrochloride.

It is a derivative of isoquinoline, which has a spasmolytic effect on smooth muscle. This occurs by the phosphodiesterase 4 enzyme inhibition process, which, accordingly, increases the concentration of CAMP, which then leads to the inactivation of the light chain of myosin kinase, leading to the effect of relaxing the smooth muscles.

It is considered to be an effective drug possessing spasmolytic action, but not leading to side effects in the cardiovascular system. The medication is used for disorders of nervous regulation and self-regulation, caused by both nervous and muscular nature. The drug has an effect on the smooth muscles located in the gastrointestinal tract, and also has a good effect on the biliary, urogenital and vascular systems. The drug has a vasodilating effect, which helps improve blood flow in the tissues. It differs by stronger action than papaverine, it is more qualitatively and quickly absorbed, less binds to blood plasma proteins, and also does not have a stimulating effect on respiratory organs.

• Duspatalin.

These pellets from abdominal pain are a spasmolytic agent with a myotropic effect that acts directly on the smooth muscles of the gastrointestinal tract, and most of all on the large intestine. It leads to the elimination of spasm, without affecting the processes of intestinal peristalsis. It has no anticholinergic effect.

• Imodium Plus.

The active component of the drug - loperamine hydrochloride - is able to bind to opiate receptors located in the walls of the intestine. This action causes inhibits propulsive peristalsis, increases the time of intestinal transit and increases the resorption of water and electrolytes. The substance does not lead to a change in the physiological intestinal microflora, and also contributes to an increase in the tone of the anal sphincter. Does not have a central effect.

Another active ingredient, simethicone, is an inert surface-active compound that has a defoaming effect. As a result, there is relief of the symptoms that cause diarrhea, as well as concomitant signs of the disease - flatulence, abdominal discomfort, bloating and spasms.

• Loperamide.

The active ingredient, loperamide, binds to opioid receptors located in the intestinal wall, thereby stimulating cholinergic and adrenergic neurons through guanine nucleotides. At the same time, the motor skills of intestinal smooth muscles decrease, the passage of intestinal contents slows down, the secretion of liquids and electrolytes with caloric masses decreases. Also, the tone of the anal sphincter increases, which leads to a better quality of fecal confinement and a reduction in the amount of urge to empty the intestine.

The action of these tablets against abdominal pain occurs quickly and lasts for four to six hours.

• Maalox.

The drug results in neutralization of the combined hydrochloric acid, while not leading to secondary hypersecretion of the acid. When using the drug, the level of acidity in the stomach increases, which leads to a decrease in the peptic activity of gastric juice. It differs by absorbing and vinolakivayuschimi qualities, which leads to a decrease in the impact of factors leading to damage to the mucous membrane.

Mezim Forte.

The preparation has in its composition a powder made from porcine pancreas and contains exocrine pancreatic enzymes - lipase, amylase, protease, trypsin, chymotrypsin, and other enzymes.

Pancreatic enzymes lead to the facilitation of the cleavage of substances such as proteins, fats and carbohydrates, which affects their absorption in the small intestine, making it more complete. Trypsin leads to suppression of stimulation of the production of enzymes by the pancreas and has an anesthetic effect. The strongest activity of the enzymes of the drug occurs in half an hour or forty-five minutes after the drug is consumed.

• But-shpa Forte.

The active active ingredient of the drug, drotaverine hydrochloride, is derived from isoquinoline. Has a powerful spasmolytic effect on smooth muscle by inhibiting phosphodiesterase. Phosphodiesterase is necessary for the process of hydrolysis of cyclic adenosine monophosphate to adenosine monophosphate.

It is established that the preparation can inhibit the effectiveness of the phosphodiesterase 4 isoenzyme, without rendering similar effects on phosphodiesterase 3 and 5. The level of drug effectiveness depends on the concentration in tissues of phosphodiesterase 4. This isoenzyme is important in suppressing the contractility of smooth muscle, which is useful in the treatment of hyperkinetic dyskinesia of various species and other and other diseases that cause spasmodic manifestations in the gastrointestinal tract.

Has shown the efficiency at spasms of a smooth musculature caused by neurogenic and muscular origin. The active component of the drug can relax the smooth muscles of the gastrointestinal tract, biliary tract and urogenital system, regardless of the type of vegetative innervation.

• Festal.

The drug is able to compensate for the problem of pancreatic secretion deficiency with pancreatin, as well as the function of bile secretion by using the bile component of the drug.

It has proteolytic, amyolitic and lipolytic effects. The action of lipase, amylase, protease - the enzymes that make up pancreatin, lead to facilitating the digestion of such food components as fats proteins and carbohydrates. Due to this, these substances are better absorbed in the small intestine.

Bile acids by their action correct biliary insufficiency, which in many cases accompanies chronic pancreatitis. Extract of bile leads to increased production of bile in the body, and also improves the absorption of fats and vitamins A, E and K, which are fat-soluble.

The action of the hemicellulose enzyme leads to an improvement in the breakdown of plant fiber, which contributes to the improvement of digestion processes and to the reduction of the formation of intestinal gases.

• Phthalazole.

These pills from abdominal pain prevent the inclusion of para-amino-benzoic acid in the production of folic acid in the cell of the microorganism. This violates the formation of folic acid, which takes part in the production of those substances that affect the growth and development of the microorganism.

The greatest effect is observed on vegetative forms of microbes, I develop consistently and gradually.

It has an anti-inflammatory effect, which is to limit the spread of leukocytes, which reduces the total amount of cellular elements and stimulates the production of glucocorticosteroids.

The medication is effective against streptococci, pneumococci, staphylococcus, meningococcus, gonococcus, Pseudomonas aeruginosa, Escherichia coli, Shigella dysentery, common protein and a number of large viruses that stimulate trachoma and follicular conjunctivitis.

Pharmacokinetics of tablets against abdominal pain

Each drug undergoes a transformation in the human body. Familiarization with the pharmacokinetics of tablets from abdominal pain will make it possible to understand these mechanisms.

• Drotaverina hydrochloride.

The active ingredient for oral use is rapidly absorbed from the gastrointestinal tract. The period of semi-absorption is a period of twelve minutes, the bioavailability of the substance is almost 100%. The maximum concentration in the blood plasma is observed from forty-five minutes to one hour.

The active component is unable to penetrate the blood-brain barrier. The processes of metabolism with the substance occur in the liver. After seventy-two hours, drotaverin is almost completely excreted from the body in the form of metabolites, half of them - with the help of urine, and thirty percent - with feces.

• Duspatalin.

The active substance does not enter the process of presystemic hydrolysis when administered orally, nor does it enter the blood plasma. Metabolism occurs in the liver, where it is converted into veratic acid and mebeverine alcohol. Metabolites are utilized from the body with the help of kidneys, but a small amount of metabolites is removed with the help of bile. Capsules have the characteristics of prolonged release. Even repeated administration of the drug does not lead to a significant cumulative effect.

• Imodium Plus.

The half-life period is ten hours, although variations can be from nine to fourteen hours for different people. Loperamide hydrochloride has the quality of easy intestinal absorption. Metabolism occurs in the liver, where its conjugation and excretion of metabolites with the help of bile occurs. Since the metabolism of the substance is very active, a fairly low concentration of the component in the unchanged form is observed in the blood. Loperamide in the form of metabolites is excreted from the body with a fecal mass. Another active ingredient, simethicone, does not possess the quality of absorption in the gastrointestinal tract.

• Loperamide.

Has intestinal absorption in the amount of forty percent. The active component binds to plasma proteins in the amount of ninety-seven percent. The half-life period is from nine to fourteen hours. Doperamide is not capable of penetrating the blood-brain barrier. The active component, getting into the systemic bloodstream, undergoes almost complete metabolism in the liver by means of conjugation. In the form of metabolites that have been conjugated, it is excreted by the bile and partially by the kidneys.

• Maalox.

Active components differ antatsidnymi qualities with local action, so they do not differ in absorption and do not have a systemic effect.

• Mezim Forte.

Tablets from abdominal pain cover an acid-resistant shell, which can not dissolve hydrochloric acid. This helps to protect the enzymes of the drug from neutralizing their activity. The shell dissolves with the subsequent release of enzymes at a level of acidity that is neutral or slightly alkaline.

• But-shpa Forte.

The active substance after oral demonstrates the quality of rapid and complete absorption, then passes pre-systemic metabolism and appears in the systemic circulation in an amount of sixty percent of the dose taken. The maximum concentration of a substance in the blood plasma is observed after an interval of forty-five minutes or one hour. The active substance has the ability of high binding to plasma proteins - from ninety-five percent. The greatest binding occurs with albumins and beta-globulins. The substance is able to distribute evenly across the tissues and penetrate into cells of smooth muscle. Not capable of penetrating the blood-brain barrier. In some quantities, the active ingredient or its metabolites can penetrate the placental barrier.

The active component undergoes complete metabolism in the liver with the help of O-de-ethylation. Its metabolites are capable of rapid conjugation with glucuronic acid.

The half-life of metabolites is a period of sixteen hours. For seventy-two hours the drug is completely removed from the body. More than half of the metabolites are excreted by the kidneys, thirty percent of the substances - through the gastrointestinal tract by excretion into the bile.

• Festal.

Enzymes of pancreatin make up for the deficiency of enzymes that the pancreas produces. They help improve digestion and assimilation of food. In the gastrointestinal tract, there is not a large percentage of absorption of pancreatin enzymes. To achieve their effectiveness, absorption is not needed, and their action occurs in the gastrointestinal tract itself.

Enzymes, moving along the gastrointestinal tract, undergo proteolytic digestion until they pass through absorption, like transformed peptides or amino acids.

Enzymes, placed in the core of the dragee, are protected from digestion in the acidic environment of the stomach by the membrane. Getting into the neutral or slightly alkaline environment of the small intestine, the membrane dissolves, and the enzymes are released. The maximum enzymatic action is carried out after half an hour or forty-five minutes after taking the medicine. Enzymes of pancreatin are not able to be absorbed, but are removed from the body with the fecal masses in a split or denatured with the help of food juices or bacteria.

• Phthalazole.

When administered orally, slow absorption occurs from the gastrointestinal tract. Only five percent of the used dose is observed in urine. This means that a large amount of active substance is concentrated in the lumen of the large intestine. There microorganisms promote the cleavage of phthalazole, from which phthalic acid, amino group and norsulfazole form. The latter substance contributes to the achievement of bacteriostatic effect in relation to the causative agents of intestinal diseases: bacillary dysentery, colitis, gastroenterocolitis. The active effect of phthalazole is most commonly observed in the intestinal lumen.

Names of tablets from abdominal pain

Here are the main names of tablets from abdominal pain that will help cope with unpleasant sensations in this area.

1. Drotaverina hydrochloride - a medicinal product is a synthetic antispasmodic, which is a derivative of papaverine.
2. Duspatalin is a drug that is a myotropic spasmolytic drug.
3. Imodium Plus is a combined antidiarrhoeal drug that suppresses intestinal peristalsis.
4. Loperamide is an antidiarrhoeal drug.
5. Maalox is a drug that is an antacid drug.
6. Mezim Forte is a digestive polyenzyme drug.
7. But-shpa Forte is a preparation of spasmolytic action.
8. Festal is a digestive drug belonging to the group of polyenzymatic preparations.
9. Phthalazole is an antimicrobial agent belonging to the group of sulfinylamide preparations.

Tablets from pain in the lower abdomen

Causes of pain in the abdomen can be different, therefore, the medicines used in this case vary in their spectrum of action. Usually, in women, the pain in the lower abdomen refers to the period of menstruation and is an unpleasant side effect of this process. But in some cases, the pain in women in the lower abdomen means the presence of an inflammatory disease of the genitourinary sphere - the ovaries, the bladder and so on. In this case, do not engage in self-treatment, and seek help from specialists. In men, the pains in the lower abdomen can also mean problems with the genito-urinary area and in this case it is not necessary to engage in self-therapy, but to seek medical advice.

Sometimes the pain in this area suggests intestinal problems, and in some cases - the presence of an oncological process in one of the organs that are in the lower abdomen.

Therefore, with an unidentified diagnosis of pain in the lower abdomen will help get rid of those tablets, a list of which was given in the previous section. This can be a one-time action, which helps to remove the patient's unpleasant and exhausting symptoms. In the future, it is necessary to turn to specialists for diagnosis, correctly established diagnosis and appropriate therapy.

Dosing and Administration

An instruction is attached to each preparation, in which the method of application and dose of each drug is described in detail.

• Drotaverina hydrochloride.

It is taken orally. Adults use one or two medication tablets three times a day. Children take a single dose of ten to twenty milligrams of medication (quarter to half tablets), the maximum daily dose at this age can be one hundred and twenty milligrams of the drug. Children between the ages of six and twelve can take a single dose of twenty milligrams (half a pill) at a maximum dose of two hundred milligrams. Use of the medicine for children - two or three times a day.

• Duspatalin.

The medication is intended for oral administration. Used twenty minutes before eating, not chewed and washed down with water. A single dose is two hundred milligrams, the drug should be taken in a single dose twice a day, in the morning and evening.

Imodium Plus.

Children of twelve years and adults take two tablets of the drug in the form of an initial dose. In the future, a single dose is one tablet of the medication used after each case of a loose stool. Within a day, up to four medicinal tablets are allowed to be used. The course of treatment should not be longer than two days.

• Loperamide.

Tablets from abdominal pain are taken inside and do not chew, they are washed down with enough water. Adults with acute and chronic manifestations of diarrhea for the first time take two capsules of medicine (four milligrams). After that, one capsule (two milligrams) of the drug is used, which are taken every time after the bowel has been emptied, if there is a loose stool. The maximum daily intake of the drug is eight capsules.

Children who are more than six years of age use one capsule of the drug for acute diarrhea after each bowel movement if there is a loose stool. The maximum amount of medicinal product that can be taken to children per day is three capsules.

The course of therapy with the drug is determined from seven to twenty days. When the stool is normalized or there is a lack of it for more than twelve hours, the medication should be finished.

• Maalox.

Tablets from abdominal pain are used orally, they must be carefully dissolve or chewed.

Adults and adolescents from fifteen years old take one or two tablets three to four times a day one or two hours after meals and before bedtime.

When reflux esophagitis is indicated, take the medication in a short time after eating.

The maximum number of medications taken is six times a day. Do not use more than twelve tablets a day. The course of therapy is two to three months.

Episodic use of the drug with the appearance of discomfort in the abdomen allows one-time use of one or two medication tablets.

• Mezim Forte.

Tablets are taken orally, not chewed and washed down with a lot of water. The dosage of the medication should be set individually, which is affected by the degree of manifestation of the disease and the composition of the food that the patient used.

The average single dose is from two to four tablets per meal. It is recommended to use half or a third of a single dose at the beginning of the meal, and the remaining amount - during the meal.

Sometimes it is possible to increase the single dose, but this happens only according to the appointment of a specialist and under his supervision. Such a change in dosage is caused by the patient's symptoms, for example, pain in the abdomen or steatori. The maximum amount of the drug per day is from fifteen to twenty thousand units of lipase per kilogram of the patient's weight.

Children take the medicine in the dosage set by the doctor. In this case, the specialist is guided by the expressed symptoms of the disease and the composition of the food taken by the child. In this case, the amount of the drug should not exceed five hundred - thousands of units of lipase per kilogram of the weight of the sick child at each meal.

The course of treatment is from several days to several months or years. Several days the drug is taken with a broken digestion and any errors in nutrition. For several months or years, a medication is used if constant replacement therapy is required.

• But-shpa Forte.

Tablets from abdominal pain are taken orally. For adults, a daily dosage of from one hundred twenty to two hundred forty milligrams of the drug is indicated. The daily dose should be divided into two or three doses. The maximum single amount of the drug is eighty milligrams. The maximum daily amount is two hundred and forty milligrams.

For children from six to twelve years of age, the drug is prescribed in a maximum daily dosage of eighty milligrams, which must be divided into two doses.

Children who are over the age of twelve, the maximum daily amount is one hundred and sixty milligrams, which must be divided into two - four portions.

The course of treatment without consulting a specialist is one or two days. If during this time there is no reduction in pain, it is necessary to consult a doctor to establish the correct diagnosis and the right treatment. If the drug is used as an element of auxiliary therapy, the course of self-treatment without consulting a specialist can be two to three days.

• Festal.

The drug is intended for internal use. It is consumed during food intake or immediately after it, while the medicine should be taken with water.

Adults take one or two pills three times a day. The child's dose is selected individually by a specialist.

The course of treatment depends on the patient's problems and can last from several days to several months or years.

• Phthalazole.

Adults take one or two tablets with a break of four to six hours. In the next two or three days it is recommended to use a half dose of the drug.

Children can use a dose of one hundred milligrams per kilogram of the child's weight per day. This portion is divided into equal shares and is taken every four hours, excluding night sleep. Then it is used from two hundred to five hundred milligrams of the drug through an interval of six to eight hours.

[5], [6], [7]

Using tablets against abdominal pain during pregnancy

Most drugs are contraindicated for use during pregnancy and lactation. To make sure of the possibility of using any medication, you need to carefully read the instructions, namely, with that section, which describes the use of tablets from abdominal pain during pregnancy.

• Drotaverina hydrochloride.

The use of the drug during pregnancy does not have teratogenic and embryotoxic effects. But, nevertheless, the medicine in this time interval should be used with caution.

There is no data on the effect of drotaverine hydrochloride on milk during the lactation period. Therefore, it should not be used during breast-feeding.

• Duspatalin.

Experiments on animals did not reveal a teratogenic effect of the active substance. The purpose of the drug during pregnancy can be carried out by correlating the benefits to the mother and the potential risk to the fetus.

The medication can be used in the lactation period, since the active ingredient is not detected in therapeutic doses in breast milk.

• Imodium Plus.

In modern medicine, there are no data on the teratogenic and embryotoxic effects of the active components of the drug. The drug is allowed to be taken during pregnancy, and especially during the first trimester, only with the available significant indications for the woman.

There is insufficient information on the isolation of active components with breast milk. A certain amount of the drug was found in breast milk, therefore, during the lactation period, the medication is not recommended.

• Loperamide.

These pills from abdominal pain are not applied in the first trimester of pregnancy. In the second and third trimesters, medication can be prescribed only if a high benefit is attributed to a mother with a low potential risk to the fetus.

It is not used during the lactation period.

• Maalox.

At this time there is no information on the presence of teratogenic effects when using tablets during pregnancy. But a small clinical experience of drug research gives permission for its use only if there is a clear benefit to the mother, which explains the possible risk to the fetus.

Large doses are not recommended during pregnancy, and you should not use the drug for a long period of time.

If the indicated quantities of the drug are used by nursing mothers, this causes a limited absorption of the active substances into the female body, which is compatible with breastfeeding.

• Mezim Forte.

Sufficient data on the effect of the drug on the course of pregnancy in women and the fetus is not available. Therefore, it can be used only if the expert is confident of the benefits of the medication for the mother and the low risk for the fetus. The same applies to the lactation period, since there is no information on the penetration of the active components of the drug into breast milk.

• But-shpa Forte.

Studies in animals have not revealed a teratogenic and embiotogenic effect of the active component of the drug. But still, you should take the medication during pregnancy only in view of the potential benefits for the mother and low risk for the fetus.

There is no data on the penetration of the drug into breast milk, therefore, during the lactation period it should not be prescribed.

• Festal.

The drug can be used during pregnancy or lactation only for acute indications, when its application has a significant benefit for the mother.

• Phthalazole.

The drug has good penetration through the placental barrier and is found in breast milk. Therefore, its use is possible only in the event that the potential risk to the fetus is minimal, and the benefit to the mother is maximal.

Contraindications to the use of tablets against abdominal pain

There are cases when the drug can not be used to stop pain. These can be diseases or certain conditions of the patient, in which you need to choose another drug. Contraindications to the use of pellets for abdominal pain are described in the manual, which must be read before using the medication.

1. Drotaverina hydrochloride.
   • The presence of hypersensitivity to the active component of the drug or to any auxiliary substance.
   • There are signs of severe hepatic and renal insufficiency.
   • Presence in the anamnesis of severe heart failure, low cardiac output syndrome.
   • Age of the patient is up to one year.
2. Duspatalin.
   • Existing high sensitivity to the active substance or auxiliary components of the medicament.
   • Children age up to 18 years.
3. Imodium Plus.
   • Has a high sensitivity to one or more of the components of the drug.
   • The presence of acute ulcerative colitis or pseudomembranous colitis, which are associated with therapy with antibacterial drugs with a wide spectrum of action.
   • It is forbidden to use the medication as a monotherapy for the treatment of acute dysentery, in which there are spotting or high fever.
   • Do not prescribe pills from abdominal pain to patients until the age of twelve.
4. Loperamide.
   • The most hypersensitivity to the components of the drug.
   • A history of lactose intolerance.
   • Presence of deficiency of lactase or ascertaining of glucose-galactose malabsorption.
   • Appearance of symptoms of diverticulosis, intestinal obstruction, ulcerative colitis in the period of exacerbation, as well as signs of diarrhea caused by pseudomembranous enterocolitis.
   • Also, the drug can not be used as a monotherapy for dysentery and other infectious diseases of the gastrointestinal tract.
   • Tablets for abdominal pain are forbidden for use by children under six.
5. Maalox.
   • The presence of severe renal failure.
   • Appearance of hypersensitivity to active or auxiliary substances of the drug.
   • The patient has hypophosphatemia.
   • Appearance of fructose intolerance.
   • The patient's age is up to fifteen years.
   • Also optional for chewable tablets with sugar:
   • Presence in the anamnesis of malabsorption syndrome of glucose-galactose.
   • The emergence of insufficiency of sucrose isomaltase.
   • For chewable tablets without sugar:
   • There are signs of intolerance to maltitol.
6. Mezim Forte.
   • Presence of hypersensitivity to pancreatin or other substances of the drug.
   • The history of acute pancreatitis.
   • Presence of exacerbation in chronic pancreatitis.
   • Hereditary factors that cause lactase intolerance.
   • Hereditary appearance of glucose-galactose malabsorption syndrome.
   • The age of patients is up to three years.
7. But-shpa Forte.
   • The presence of high sensitivity to the active component of the drug or excipients.
   • There are symptoms of severe hepatic or renal insufficiency.
   • The presence of severe heart failure and low cardiac output syndrome.
   • The patient's age is up to six years.
   • Presence of hereditary intolerance to galactose, as well as signs of hereditary lactase deficiency and glucose-galactose malabsorption syndrome.
   • Caution should be used in patients with hypertension, as well as patients with age from six to eighteen years.
   • The presence of exacerbated erosive and ulcerative diseases of the gastrointestinal tract, for example, peptic ulcer of the stomach and duodenum, Crohn's disease, ulcerative colitis.
   • The presence of hemophilia and other diseases that indicate problems with blood coagulability, including hypocoagulation, as well as the appearance of hemorrhagic diathesis.
   • Available in the history of the patient period after aortocoronary bypass surgery.
   • The occurrence of bleeding from the gastrointestinal tract, as well as the appearance of intracranial hemorrhages.
   • The presence of severe hepatic insufficiency or any other hepatic diseases in the active stage.
   • The presence of severe renal failure.
   • The presence in the patient's history of confirmed hyperkalemia.
   • The patient's age is up to twelve years.
8. Festal.
   • The presence of high sensitivity to one of the components of the drug.
   • The onset of acute pancreatitis.
   • Presence of exacerbation of chronic pancreatitis.
   • The onset of liver failure.
   • The appearance of hepatitis.
   • Presence of mechanical jaundice.
   • The onset of cholelithiasis.
   • Appearance of the empyema of the gallbladder.
   • The onset of intestinal obstruction.
   • The patient's age is up to six years.
9. Phthalazole.
   • The presence of hypersensitivity to drugs from the sulfonamide group.
   • Available in the anamnesis of the disease of the blood system.
   • The presence of hyperthyroidism.
   • The onset of chronic renal failure.
   • The appearance of glomerulonephritis.
   • The presence of acute hepatitis.
   • The onset of intestinal obstruction.
   • The patient's age is up to three years.
   • Presence of deficiency of lactase.
   • The occurrence of lactose intolerance, as well as glucose-galactose malabsorption.
   • Care must be taken with nephritis.

[3], [4]

Side effects of tablets against abdominal pain

Virtually all drugs are characterized by the appearance of undesirable effects after their application. Side effects of tablets against abdominal pain may be different, depending on the active substances of the drugs.

Drotaverina hydrochloride.

• Gastrointestinal tract: the appearance of constipation and nausea.
• Nervous system: the onset of headache, dizziness, insomnia.
• Cardiovascular system: the appearance of rapid heart rate and hypotension.

Duspatalin.

• These pills from pain in the abdomen are well tolerated.
• In some cases, allergic reactions may occur.
• It is also possible the appearance of nausea, headache and dizziness.

Imodium Plus.

• There are no signs of serious side effects from even prolonged use of loperamide.
• In some cases, there may be a reaction of hypersensitivity to the components of the preparation in the form of dermal ones. There are information about single cases of anaphylactic shock and bullous eruptions, which had the appearance of even toxic epidermal necrolysis.
• In the case of side effects, the cause of their appearance was the simultaneous use of certain drugs that led to the appearance of allergic reactions.
• Sometimes there is a constipation with a parallel swelling of the abdomen.
• In very rare cases, paralytic intestinal obstruction may appear. But even in such patients, this effect only arose if the recommendations given by the doctor were violated.
• Rarely there are signs of abdominal pain or abdominal discomfort, nausea and vomiting, high fatigue, drowsiness, dizziness and dry mouth.

Loperamide.

• Appearance of symptoms of discomfort in the abdomen, flatulence, gastralgia, intestinal colic, constipation, intestinal obstruction.
• Appearance of dryness in the oral cavity.
• The appearance of allergic reactions in the form of skin rashes and urticaria.
• Appearance of nausea and vomiting.
• The appearance of headaches, dizziness, drowsiness or signs of insomnia.
• Occurrence of delays in urination.

Maalox.

• If you adhere to the recommendations of experts, the appearance of side effects can be in small quantities.
• The immune system is the appearance of hypersensitivity to the components of the drug, which are expressed in the form of itching, hives, angioedema and anaphylactic reactions.
• Gastrointestinal tract - the appearance of diarrhea or constipation.
• Exchange processes - the appearance of hypermagnesia, hyperaluminia, hypophosphatemia, which leads to an increase in the resorption of bone tissue. Such side effects occur if the duration of the course of treatment is violated, or the dosage of tablets is from abdominal pain. There may also be signs of hypercalciuria and osteomalacia.

Mezim Forte.

• In medical practice, there is no evidence of side effects or any complications. Even prolonged and regular use of pellets for abdominal pain in patients with pancreatic problems did not lead to side effects.
• In some cases, the appearance of allergic manifestations.
• Rarely are there cases of diarrhea or constipation, nausea, and discomfort in the epigastric region.
• Patients who have a history of cystic fibrosis disease can observe the appearance of hyperuricosuria, which is characterized by an elevated uric acid content in the blood serum. This occurs only with prolonged use of the drug in high dosage.
• Sometimes in patients with cystic fibrosis strictures in the ileocecal region and the ascending part of the intestine can form.

But-shpa Forte.

• Cardiovascular system - in rare cases, there are symptoms of rapid heart rate, as well as low blood pressure.
• The central nervous system is the appearance of headache, dizziness and insomnia.
• Gastrointestinal tract - in rare cases, symptoms of nausea and constipation may occur.
• Immune system - in rare patients there are manifestations of allergic reactions, namely angioedema, urticaria, rash, itching.

Festal.

• Digestive system - the appearance of nausea, diarrhea, pain in the abdomen, a decrease in the production of bile acids of endogenous nature.
• Allergic reactions - the appearance of urticaria, itching of the skin.

Phthalazole.

• Digestive system - the appearance of nausea, vomiting, diarrhea, oral lesions in the form of stomatitis, gingivitis, glossitis, the emergence of gastritis, cholangitis, hepatitis, insufficiency of vitamins from group B, which is a consequence of oppression of the intestinal microflora.
• System of blood - symptoms of leukopenia, thrombocytopenia, agranulocytosis, hemolysis of erythrocytes can rarely appear. Prolonged use of the drug leads to the formation of anemia, which is a consequence of the low content of pantothenic and ptero-glutaric acids, which are produced by microorganisms.
• Cardiovascular system - the appearance of myocarditis and cyanosis.
• Nervous system - the occurrence of headaches, dizziness, depressed mood.
• The respiratory system is the appearance of eosinophilic pneumonia.
• Urinary system - the occurrence of urolithiasis.
• Allergic reactions and manifestations of toxic-allergic nature - the emergence of a drug allergy, which manifests itself in the form of skin eruptions, which can be similar even to nodular or multiform erythema. In some cases, the appearance of epidermal necrolysis. Sometimes there are symptoms of allergic edema of the lips and face, as well as nodular periarteritis.

Overdose

Overdose, usually, appears in cases when the recommendations of a specialist or the method of admission described in the instruction are violated. This occurs when the patient starts taking large doses of the drug alone or uses it for a long time.

Drotaverina hydrochloride.

• There are no data on cases of overdose.

Duspatalin.

• In case of an overdose, symptoms of overexcitation of the central nervous system may appear.
• In such cases it is shown to wash the stomach, take activated charcoal or another sorbent, and also apply symptomatic treatment.
• There is no specific antidote to the drug.

Imodium Plus.

• When an overdose occurs, violations of the liver function, which affects the central nervous system. There are symptoms of stupor, impaired coordination, drowsiness, miosis, muscle hypertonia, inhibition of breathing. Patients of childhood age experience symptoms of central nervous system inhibition in more frequent cases than adults.
• There are also signs of paralytic intestinal obstruction.
• Before the appearance of symptoms of an overdose to the patient, it is necessary to introduce an antidote such as Naloxone. The duration of the action of Imodium Plus is greater than Naloxone, therefore, it is possible to introduce a second amount of the antidote.
• To establish the effectiveness of antilototherapy, which consists in the absence of signs of inhibition of the central nervous system, the patient should be under the supervision of specialists for two days.

Loperamide.

• The appearance of signs of central nervous system depression in the form of stupor, coordination disorder, drowsiness, miosis, muscle hypertension, respiratory depression.
• There may also be signs of intestinal obstruction.
• In these cases it is necessary to resort to the use of the antidote Naloxone.
• The action of Loperamide is much longer than that of Naloxone, therefore, repeated administration of the antidote is required.
• Symptomatic therapy may also be used in the form of activated charcoal, gastric lavage, artificial ventilation of the lungs.
• When symptoms of an overdose occur, the patient needs to be observed by specialists in a hospital for two days.

Maalox.

• The appearance of diarrhea, pain in the abdomen and vomiting.
• Patients at risk may experience the appearance or aggravation of bowel obstruction or intestinal obstruction. These patients include those with renal insufficiency, patients who have a history of porphyria, to which hemodialysis is applied, patients with Alzheimer's disease, diabetes mellitus, and elderly people.
• When symptoms of an overdose appear, use of a large amount of fluid is shown to force diuresis. This is necessary because the preparations of aluminum and magnesium are excreted from the body by means of urine. To patients who have renal failure, it is necessary to apply hemodialysis or peritoneal dialysis.

Mezim Forte.

• There is no evidence of drug overdose and cases of intoxication.
• In some patients, there may be symptoms of hyperuricosuria and hyper-uremia.
• Constipation may occur in pediatric patients.
• When unwanted symptoms appear, it is necessary to cancel the drug and prescribe symptomatic therapy.

But-shpa Forte.

• Violation of the rhythm of the heartbeat and cardiac conduction, which can lead even to a complete blockade of the legs of the bundle and stopping the heart, in some cases taking a fatal appearance.
• In case of an overdose, the patient should be placed in a hospital under the supervision of specialists. If necessary, they are given symptomatic and supportive therapy, which also includes procedures for the induction of emetic reflexes and gastric lavage.

Festal.

• If tablets from abdominal pain are used for a long time and in a large dosage, this can lead to an increase in the level of uric acid in the blood plasma and urine.
• Children with the use of large doses of medicines experience the appearance of skin irritation, which affects the perinatal area and the mucous membrane of the oral cavity.
• In case of an overdose, symptomatic therapy is indicated.

Phthalazole.

• In this case, there are signs of pancytopenia, in which the number of all blood cells drops sharply.
• Sometimes there is nausea, vomiting and headache.
• In these cases, the drug is withdrawn and symptomatic treatment is prescribed, if necessary.

Interactions of tablets against abdominal pain with other drugs

It happens that with the simultaneous reception of various drugs, there are undesirable effects. Therefore, it is very important to get acquainted with the section of interaction of tablets from abdominal pain with other drugs and eliminate unnecessary combinations.

• Drotaverina hydrochloride.

Simultaneous use of levodopa and drotaverine hydrochloride leads to a weakening of the antiparkinsonian effect from the first substance.

• Duspatalin.

There were no drug interactions with other drugs. Therefore, the medication can be used with simultaneous reception with any medications.

• Imodium Plus.

The only interaction with drugs with a similar antidiarrheal effect was noted. Other drug interactions were not observed.

• Loperamide.

The simultaneous use of tablets against abdominal pain and opioid analgesics or Colestyramine can lead to the appearance of severe constipation. Parallel use of Co-trimoxazole, Ritonavir leads to an increase in the bioavailability of the active component of the drug, which causes the inhibition of its metabolism during its first passage through the liver.

• Maalox.

If it is used together with quinidine, then an increase in the concentration of quinidine in the serum and the occurrence of an overdose of quinidine.

With simultaneous use of blockers of histamine receptors, propanol, atenolol, cefpodoxim, metoprolol, chloroquine, prostacyclin, diflunisalon, digoxin, bisphosphonate, etambatol, isoniazid, fluoroquinolones, sodium fluoride, prednisolone, dexamethon, indomethacin, ketoconazole, lincosamides, phenothiazine antipsychotics, penicillamine, rosuvastatin , iron salts, levothyroxine and drug, there is a decrease in the absorption of the above medicines into the gastrointestinal tract. If there is a two-hour interval between taking these medications and maalox and a four-hour interval between taking fluoroquinolones and maalox, an undesirable effect of the drug is not observed.

With the simultaneous use of polystyrene sulfonate (cayexalate) and the drug, caution is necessary because of the potential for low potassium binding of resin and the appearance of symptoms of metabolic alkalosis in patients with renal insufficiency, and the appearance of intestinal obstruction.

With the simultaneous use of it and citrates, an increase in the concentration of aluminum in the blood serum is observed, especially in those patients who suffer from kidney failure.

• Mezim Forte.

Tablets from abdominal pain that contain pancreatin, and Mezim Forte with simultaneous intake reduce the absorption of folic acid. Sugar-reducing drugs, such as Acarbose and Miglitol, reduce their effectiveness if taken together with pancreatin, which is part of the drug.

Joint use of medicines and iron preparations leads to a possible decrease in the level of absorption of drugs, including iron in their composition.

With the simultaneous use of medication and antacid preparations, which include calcium carbonate or magnesium hydroxide, leads to a decrease in the quality of the action of Mezima Forte.

• But-shpa Forte.

The joint administration of levodopa and No-shpov lead to a decrease in the antiparkinsonian action of the first drug. In this case, rigidity and tremor, characteristic of the disease, are increasing.

Other antispasmodic drugs, for example, including m-holinoblokatory, lead to an increase in spasmolytic effect.

Interaction with drugs that have the quality of high binding to blood plasma proteins (over eighty percent): there is no data on it. Although there is an assumption about the possibility of their interaction with drotaverine, which manifests itself at the level of their connections with plasma proteins. This can cause certain pharmacodynamic or toxic side effects of No-shpa.

• Festal.

Simultaneous use leads to increased absorption of drugs that have in their composition para-aminosalicylic acid. The same effect is experienced by sulfonamides and antibacterial drugs.

Joint use can lead to a decrease in the level of absorption of drugs containing iron.

Simultaneous use with antacid medicines that contain calcium carbonate or magnesium hydroxide leads to a decrease in the efficacy of Festal.

• Phthalazole.

It is allowed to use simultaneously with antibacterial medicines from different groups, which leads to an increase in the antimicrobial effect.

Sulfonamide drugs, taken simultaneously with the drug, lead to an increase in its effect and an expansion of the spectrum of effects. It is allowed to use the drug and sulfonamides, which are distinguished by good absorption into the blood. This applies to Biseptol, Ethazol, Ethazol-sodium, Sulfadimezin.

It is forbidden to use together with some drugs, namely PASK derivatives - Novocain, Anestezin, Dicain; barbiturates - Pentobarbital, Phenobarbital, Phenobarbital and so on; salicylates - Aspirin, Aspirin-Cardio; Diphenyl; Oxacillin; nitrafurans - furazolidone and others; hormonal drugs and oral contraceptives; Calcium chloride, vitamin K, thiocetazone, levomycetin, hexamethylenetramine, adrenaline; anticoagulants of indirect action - Warfarin, Thrombostop and others.

It is forbidden to use the drug and enterosorbents, as well as laxative drugs. Reception of enterosorbents can be only one hour after using the medication.

Tablet storage conditions for abdominal pain

Each preparation needs special characteristics for its content. The correct storage conditions for tablets from abdominal pain make it possible to effectively use the drug throughout its useful life.

1. Drotaverina hydrochloride - the drug must be stored in a place that is protected from moisture and light, and from penetration of children, at a temperature not exceeding twenty-five degrees Celsius.
2. Duspatalin - the drug should be kept out of reach for children, in a dry place at a temperature of five to thirty degrees Celsius.
3. Imodium Plus - the drug should be stored in a place that is inaccessible to children, at a temperature of fifteen to thirty degrees Celsius.
4. Loperamide - the drug should be kept in a dry room, which is protected from sunlight and penetration of children, at a temperature not exceeding twenty-five degrees Celsius.
5. Maalox - the drug is stored in a place inaccessible to children of children and at a temperature not exceeding twenty-five degrees Celsius.
6. Mezim Forte - the medication is contained in a dry and dark place, where there is no access for children at a temperature of up to twenty-five degrees Celsius.
7. But-Fort Forte - the drug is stored at ambient temperatures up to twenty-five degrees Celsius, in a place where children can not penetrate.
8. Festal - is kept at a temperature of up to twenty-five degrees Celsius in the place where moisture and children's faces do not penetrate.
9. Ftalazol - placed in a place inaccessible to children, which is protected from moisture and sunlight, at temperatures up to twenty degrees Celsius.

Shelf life

The expiration date of each drug is indicated on a cardboard pack or other packaging of the drug.

1. Drotaverine hydrochloride is two years from the date of release.
2. Duspatalin is thirty-six months from the date of manufacture.
3. Imodium Plus - two years from the date of issue.
4. Loperamide is thirty-six months from the date of manufacture.
5. Maalox is five years from the date of issue.
6. Mezim Forte - three years from the date of production.
7. But-shpa Forte - five years from the date of production.
8. Festal - thirty-six months from the date of production.
9. Ftalazol - four years from the date of release.

Tablets from abdominal pain are not a panacea, but a first aid device in those cases in which self-medication is possible. And even when the problem is known to the patient, it is best not to deal with his own therapy, but resort to the help of specialists.