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Vasoserk
Last reviewed: 09.08.2022
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Vasoserk is a histamine-like drug acting on the vestibular system, ATS code N07C A01. Other trade names of the drug: Betagistin, Betagis, Betaserk, Betanorm, Betaver, Vestinorm, Vestibo, Vestikap, Vestagistin, Asniton, Avertid, and others.
Indications of the vasoceros
The drug Vasoserk is used to treat the following vestibulo-cochlear disorders:
- disease and Ménière syndrome;
- inflammation of the inner ear (labyrinthitis);
- acute peripheral vestibulopathy (vestibular neuritis);
- vertebrobasilar insufficiency of different etiology;
- dizziness;
- noise in the ears;
- progressive hearing loss with edema of the labyrinth of the inner ear;
- encephalopathy associated with brain trauma and surgical intervention.
Vasoserk can also be used in complex therapy of circulatory disorders of the brain, including atherosclerosis of blood vessels.
Release form
Form release: tablets of 16 and 24 mg (in the packaging of 30 tablets).
Pharmacodynamics
The active substance of the drug Vasoserk - beta-histidine dihydrochloride - inactivates the enzyme diaminoxidase, which blocks the release of the biogenic neurotransmitter
Histamine, and also activates its receptors (H1 and H3) in the inner ear and nuclei of the pre-vertebral (vestibular) nerve.
This helps to increase microcirculation in the capillaries of the inner ear and stabilize the pressure of the endolymph, which fills the system of the cochlear path and the spiral organ of the inner ear, reducing the intensity of dizziness, reducing tinnitus and improving hearing. In addition, Vasoserk dilates the vessels of the brain.
Pharmacokinetics
After oral administration, Vasoserk is rapidly absorbed in the gastrointestinal tract; the maximum concentration in the blood plasma reaches 3 hours after admission.
The association of beta-histidine dihydrochloride with blood proteins is negligible.
Metabolism Vasoserk occurs in the liver - with the formation of two metabolites, which are eliminated with urine, the term of their half-elimination is 4 hours, complete elimination - 72 hours.
Use of the vasoceros during pregnancy
Use Vasoserk during pregnancy and during lactation is contraindicated.
Contraindications
Vasoserk is contraindicated for hypersensitivity to histamine, bronchial asthma, pheochromocytoma (tumors of adrenal chromaffin cells), peptic ulcer of the stomach or duodenum, and also at the age of 18 years.
Side effects of the vasoceros
Among the possible side effects of Vasoserk are: nausea, headache, dyspepsia, increased heart rate, a feeling of squeezing in the head or chest, a feeling of discomfort or pain in the epigastric region.
[1]
Overdose
Overdose Vasoserk causes nausea, vomiting and convulsions. With such symptoms, you should wash the stomach and take a sorbent, for example, activated charcoal.
Shelf life
Shelf life - 24 months.
[11]
Attention!
To simplify the perception of information, this instruction for use of the drug "Vasoserk" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.