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Vasoquette
Last reviewed: 03.07.2025
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Vazoket belongs to the group of angioprotectors - drugs that reduce the permeability of blood and lymphatic vessels and normalize biochemical processes in their walls.
International nonproprietary name: Diosmin, other trade names (synonyms): Dioflan, Phlebodia 600, Phlebofa, Diovenor 600, Mediven.
Indications Vasoqueta
The drug Vazoket is used for varicose veins of the lower extremities, chronic lymphovenous insufficiency of the lower extremities, acute hemorrhoids and exacerbation of chronic hemorrhoids, as well as for disorders of capillary microcirculation and increased fragility of capillaries.
Release form
Vazoket is available in tablet form - oblong tablets of 600 mg in blister packaging.
Pharmacodynamics
Vazoket contains the active substance diosmin - a flavonoid of plants of the genus Rutaceae and Vicia 7-rutinoside diosmetin, which has antioxidant properties, as well as the phenolic glycoside of citrus peel hesperidin, which has P-vitamin properties and has a strengthening effect on capillaries.
Vazoket helps to reduce the distensibility and increase the tone of veins and lymphatic vessels, reducing venous blood congestion in the vascular system and activating lymph outflow.
The active ingredients of the drug Vazoket reduce the permeability of the vessel walls, reduce the inflammatory effect of leukocytes on the endothelium lining their inner surface and the migration of leukocytes into paravascular tissues. The anti-inflammatory effect of the drug is also achieved by inhibiting lipid peroxidation, reducing the production of inflammation mediators thromboxane and prostaglandins.
The complex effect of Vazoket significantly reduces the intensity of clinical symptoms of venous circulatory insufficiency.
Pharmacokinetics
The active substances of Vazoket are absorbed in the gastrointestinal tract, entering the superficial and hollow veins of the lower extremities, as well as many tissues and organs, including the liver, kidneys and lungs. The highest concentration in the blood plasma is noted 5 hours after taking the therapeutic dose, in the vascular tissues - after 9 hours.
The drug can remain in the body for four days. Almost 80% of the drug is excreted by the kidneys, the rest - through the intestines.
Dosing and administration
Vazoket tablets are taken orally. In case of varicose veins, take 1 tablet during the day (in the morning, after meals); the course of treatment is 2 months; in case of severe venous insufficiency - 5-6 months.
For acute hemorrhoids, 2-3 tablets per day are prescribed (meal time), the course of treatment is a week with a possible extension of the drug intake for 1-2 months (1 tablet per day).
Overdose of the drug Vazoket is not described in the official instructions.
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Use Vasoqueta during pregnancy
Use during pregnancy - in case of lymphovenous insufficiency - is permissible under strict prescription of the attending physician. It is not recommended to use during lactation, since there is no data on the penetration of the drug into breast milk.
Contraindications
Contraindications to Vazoket include individual hypersensitivity to diosmin or hesperin, as well as age under 18 years.
Side effects Vasoqueta
Overdose
Symptoms of overdose have not been described.
Interactions with other drugs
The simultaneous use of Vazoket with drugs containing adrenaline, noradrenaline, epinephrine or norepinephrine enhances the vasoconstrictive effect of the latter.
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Storage conditions
Storage conditions: at room temperature.
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Shelf life
The shelf life is 3 years.
Attention!
To simplify the perception of information, this instruction for use of the drug "Vasoquette" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.