Vazar N

Vazar N is a drug that has hypotensive properties. Simply put, it can lower blood pressure. The main active ingredient is valsartan. It performs a number of basic functions that are intended for the drug. The drug is used everywhere, but it is worth knowing the main indications.

Indications Vazar N

What do the main indications for the use of Vazar N say? So, the main property of the drug is to reduce blood pressure. Therefore, it is widely used for arterial hypertension. Naturally, people with cardiovascular diseases fall into this category.

The main focus is on problems associated with chronic heart failure. The drug is taken with special caution, because it is not suitable for everyone.

The medication can only be used with the permission of a doctor. You cannot take the drug on your own, because it can provoke a strong "drop" in pressure. It is worth starting from the existing problem and its features. After all, the individual "qualities" of the body play a large role.

Today, cardiovascular problems are among the most common. Therefore, it is important to start correct and timely treatment. The effective drug Vazar N will help to cope with the main problems and improve well-being.

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Release form

The release form depends on the concentration of the active substance. So, the drug is released in the form of tablets. No suspensions, balms, etc. Only tablets! This should be taken into account when buying. After all, there are quite a lot of similar drugs and it is easy to make a mistake.

Depending on how much active substance is contained in the tablets, the release forms are distinguished. Thus, the product can be purchased for 40 mg, 80 mg and 160 mg. In order not to make a mistake in such a variety, the colors of the tablets were made different. The drug with a small amount of active substance has a 40 mg release form of a yellow tint.

Tablets with 80 mg of valsartan are pink. The drug for 160 mg also has a yellow tint. These data are necessary, take into account when buying. The composition of the drug also contains hydrochlorothiazide, in an amount of 0.0125 to 0.025 g. Naturally, this also depends on the color of the tablets and their action. When buying Vazar N, you must not forget about these criteria.

Pharmacodynamics

Pharmacodynamics of the drug indicate that the main active ingredient is valsartan. It is an angiotensin receptor antagonist intended for oral use.

The active substance selectively affects the receptors responsible for the functions of angiotensin. Valsartan is able to affect the cardiovascular system. At the same time, it does not block other hormonal receptors or ion channels.

The hypotensive effect of the drug begins to be noted within 2 hours after taking it. The pressure is maximally reduced after 4-6 hours. To do this, it is enough to take the drug once.

After using the product, the effect lasts for one day. If a course of treatment is used, the pressure decreases for 2-4 weeks and does not bother a person at all. Moreover, it can be maintained throughout the entire time. An additional decrease is observed due to the content of hydrochlorothiazide in the drug, which enhances the effect of valsartan. Refusal to use Vazar N does not cause a withdrawal function.

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Pharmacokinetics

After taking the drug orally, it is absorbed quite quickly, this is its pharmacokinetics. As for the bioavailability of the drug, it is 23%.

Valsartan is directly bound to plasma proteins. It is due to this penetration that it exerts its effect. After a person takes the drug, almost 83% of it will be excreted. Moreover, the excretion process occurs, along with feces, almost unchanged. About 13% of the drug comes out with urine. Hence the conclusion that almost nothing is retained in the body.

The product is actually very effective due to the content of two powerful components. In their original form, they could not have such an effect. In addition, their complete interaction allows almost all components of the drug to be removed from the body. Vazar N is one of the powerful medications whose main action is aimed at lowering blood pressure and maintaining the effect for a long time.

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Dosing and administration

The method of administration and dosage of Vazar N is prescribed by the attending physician. But there is also a generally accepted dosage, which is worth starting from. The average therapeutic dose is 0.16 mg per day. If there is an extreme need, then it is doubled. But this is done only after consultation with the doctor. Simultaneous use of the drug is also possible, but together with other antihypertensive medications.

The initial dose in the presence of chronic heart failure is only 0.04 g. But the drug should be taken twice a day. Gradually, the dose is increased to 0.16 g.

In the post-infarction state, the dosage is small, only 0.02 g, it also reaches 0.16 g over time. The drug should be taken with special caution by people with renal artery stenosis. Especially if potassium-containing medications and potassium-sparing diuretics are used simultaneously.

Constant monitoring is also necessary at the initial stage of treatment of chronic heart failure, liver cirrhosis and the post-infarction period. Especially if ACE inhibitors are used at this time. When liver diseases are observed, the dose should in no case be higher than 0.08 g. Therefore, Vazar N should be taken with special caution.

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Use Vazar N during pregnancy

The use of Vazar N during pregnancy is contraindicated. The fact is that during this period, special care must be taken. This is especially true for the first trimester of pregnancy. At this time, the body of the mother and baby is weakened. The formation of the main processes begins and this cannot be spoiled. The use of the drug can lead to serious problems.

During lactation, you should also not resort to using this medication. In general, you need to reduce the intake of any drugs, because they can negatively affect the health of the child.

Any decisions regarding the use of this or that remedy must be strictly agreed upon with the doctor. You cannot do anything on your own. All this is fraught with serious problems. The drug itself will not affect the baby's cardiovascular system, but its active substances can negatively affect health and further development. Therefore, the drug Vazar N is strictly prohibited.

Contraindications

The main contraindications to the use of Vazar N are individual intolerance to some components of the drug. Increased sensitivity to valsartan can lead to the development of serious allergic reactions.

A similar situation can be caused by auxiliary components, such as hydrochlorothiazide. What are the risks of using this drug? Do not think that the medication is completely harmless. It has a tremendous effect on the body. But, despite the fact that it helps to get rid of the problem, it can also worsen the condition.

People with severe liver dysfunction should not take the drug under any circumstances. A similar rule applies to patients suffering from cirrhosis, bile outflow disorders, kidney function and hemodialysis. That is why a doctor's consultation is mandatory. Vazar N cannot be prescribed independently; there must be special grounds for this, supported by medical evidence.

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Side effects Vazar N

Are there any side effects of Vazar N and how to effectively combat them? The first reaction that may occur is orthostatic hypotension. It is possible that infections of the upper respiratory tract and paranasal sinuses may develop. In other words, sinusitis and pharyngitis may develop.

In extremely rare cases, conjunctivitis, heart failure, hypotension occur. Abdominal pain may occur, which indicates negative processes in the gastrointestinal tract. Back pain, arthritis, and asthenia are not excluded.

It is quite possible that neurological disorders may develop. A person may become depressed, suffer from insomnia and neuralgia. During a blood test, thrombocytopenia and hyperkalemia may be detected, which can cause bleeding. In exceptional cases, renal failure, renal dysfunction and even gastroenteritis may occur. This listing is quite sufficient to understand one fact: you cannot take Vazar N on your own.

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Overdose

An overdose of Vazar N may well occur if the drug is taken incorrectly. The symptom of this event is arterial hypotension. Moreover, it is often accompanied by dizziness. If this symptom occurs, the person urgently needs to lie down and administer a saline solution. It is not advisable to prescribe dialysis. After all, the drug is largely associated with blood plasma proteins.

Heart failure or shock may develop. If a person takes too much, nausea, drowsiness, hypovolemia, and electrolyte disturbances may occur.

In case of overdose, you should immediately wash out your stomach. But this rule only works if the drug was taken recently. A doctor's examination is mandatory. He must determine the patient's condition and decide what to do next. To ensure that overdose symptoms never occur, you just need to follow the recommendations and not increase the dose yourself. In this case, Vazar N will not cause harm.

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Interactions with other drugs

Interactions with other drugs are possible, but this process must be monitored and agreed upon with a doctor. Special caution is required if a person is taking medications aimed at increasing potassium in parallel. After all, the concentration of this substance in the blood can increase significantly.

A special category includes such substances as warfarin, indomethacin, atenolol, furosemil and hydrochlorothiazide. It is not recommended to combine them with this drug. No interactions between these medications have been found.

When prescribing Vazar N together with antihypertensive drugs, the antihypertensive effect may increase. In this case, a doctor's consultation is necessary. Nonsteroidal anti-inflammatory drugs may lead to a decrease in the hypotensive effect. Renal dysfunction, which is reversible and temporary, cannot be ruled out.

In extremely rare cases, such a combination of drugs leads to renal failure. But this happens mainly in elderly people. Which means that you should be careful when taking Vazar N with other medications.

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Storage conditions

Storage conditions for Vazar N are a dark place with a temperature of no more than 25 degrees. For many drugs, this is a generally accepted norm. But this is still not enough. Sunlight should not penetrate to the medicine. Dampness is also prohibited, because under its influence the drug can deteriorate.

The effect of high temperature has a negative effect on the medicine. The blister in which the tablets are located may swell. This indicates that this medicine can no longer be taken.

It is necessary to protect the tablets from children. After all, due to their interesting coloring, they attract the attention of children. A child may well drink them, mistaking them for candy. The strong effect of the drug on a child's body can lead to irreversible processes.

If the tablets have been open for a long time, you need to look at their external data. If they change, you should stop using the medicine. In general, Vazar N is unpretentious and can be stored under normal conditions.

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Shelf life

The shelf life of the drug depends on many factors. This also applies to storage conditions. The medicine can last for 2 years, but only if you provide it with a decent "life".

So, it is necessary to observe special conditions. First of all, it should be a warm, dry place, where there is no dampness at all. The temperature regime is also special, it does not exceed 25 degrees. The product cannot be frozen, this will lead to it losing its main properties.

It is necessary to pay attention to the appearance of the blister. If it is punctured or swollen, the tablets are most likely completely unusable. This is also indicated by a change in appearance and smell. This criterion is important if you do not want to get poisoned.

Direct sunlight should not touch the medicine, this will protect it from spoilage. Compliance with all the rules in combination will allow storing the drug for a specified period of time, namely 2 years. Vazar N is not particularly capricious to storage conditions, but, nevertheless, they must be observed.