It is not desirable to take Ursoliv in combination with anti-acid agents, with preparations of Kolestyramin, Kolestipol, Smekta, Almagel, since such medications worsen the absorption of ursodeoxycholic acid in the intestinal cavity. If a combination of medications is inevitable, then between their use should withstand a gap of 120 minutes.
Ursoliv can affect the absorption of Ciclosporin in the intestinal cavity. With this combination, you should monitor the level of Cyclosporine in the blood and, if necessary, change the dosage.
In some patients, taking Ursoliv may impair the absorption of ciprofloxacin.
The combination of Ursoliv and Rosuvastatin may lead to an increase in the concentration of rosuvastatin in the serum.
It is known that Ursoliv lowers the limiting serum concentration of Nitrendipine in patients with normal liver and kidney function.
It is necessary to monitor the patient's condition while treating Ursoliv and Nifedipine. In some cases, you may need to increase the dosage of Nifedipine.
It is indicated that the therapeutic effect of Dapson in combination with Ursoliv is weakened.
Preparations based on estrogen, as well as means for normalizing the level of cholesterol in the bloodstream, can increase the release of cholesterol in the liver and increase the risk of formation of concrements in the system of bile formation.