Truxal

Chlorprothixen is a medical product that is characterized by a relatively mild effect and a high degree of effectiveness.

[1], [2], [3], [4],

Indications of the chloroprotxene

Chlorprotixen may be required if the patient suffers from:

• Psychoses, including schizophrenia and manic conditions, which are accompanied by psychomotor agitation and anxiety;
• The state of depression during menopause;
• Attacks of excitement, which are interrelated with fear and tension;
• Dyscirculatory encephalopathy;
• ITC;
• Abstinence syndrome with alcohol and drug abuse;
• Hyperactivity, irritability, agitation, mixed consciousness in elderly patients;
• Sleep disorders with increased anxiety;
• Premedication;
• Increased anxiety (including patients with burns);
• Overthrowing dermatosis;
• Bronchial spasm;
• Pain syndrome (in combination with analgesics).

For children, the medication can be used for psychotic and neurotic pathologies, as well as for behavioral disorders.

[5], [6], [7]

Release form

The drug on the pharmaceutical market is presented as:

1. A pill of ten pieces in a plate;
2. Droplets
3. R-ra for injection of 2 ml (50 mg) of ten or one hundred ampoules in a box.

[8], [9], [10], [11]

Pharmacodynamics

Antidepressant component in the psychotropic effect, distinguishes Chlorprothixen from Aminazine.

[12], [13], [14],

Pharmacokinetics

After the medication enters the body, it is rapidly absorbed and metabolized in the liver. Basically, in an unchanged form, Chlorprothixene is excreted with feces and urine.
When the drug is administered intramuscularly - the soothing effect is manifested after ten to thirty minutes.

[15], [16], [17], [18]

Dosing and administration

The medicine can be used both inside (before eating), and in the form of injection (intramuscularly).
Dosage is due to the patient's well-being and the severity of the pathological process to which he suffers.
Psychosomatic pathologies and severe depressive diseases:
In this case, Chlorprotixen is prescribed in the role of an additional medication in combination therapy. As a rule, for a couple of uses, the dose per day reaches values from sixty to ninety milligrams.
Psychoses, schizophrenia, manic disorders:
At the beginning of treatment, Chlorprothixen is used from fifty to two hundred milligrams per day, then the dosage is increased to two hundred and fifty to three hundred milligrams. In exceptional cases, you can increase the dosage to 1200 mg (but when divided into one-time receptions it is worth remembering that most, about forty percent, should be in the evening time). Supportive treatment - the use of one hundred two hundred milligrams a day.
Neuroses:
You need to drink medication before bed, ten to fifteen, sometimes thirty, in an exceptional case, forty-five milligrams.
Abstinence syndrome ("hangover", postnarcotic state):
Five hundred milligrams of medication should be divided into three uses throughout the day. Should be taken so from five to seven days. To reduce the likelihood of developing a breakdown, in the role of a maintenance dose, after the treatment, the dose should be reduced to 15 - 45 mg per knock.
An elderly category of patients who have a pronounced increased activity, quick temper, confusion, nervous overexcitation:
Treatment starts from fifteen to ninety milligrams per day, and gradually rising to the desired effect.
A sleep disorder that manifests itself in the form of insomnia:
One hour before the desired time to fall asleep, you need to consume from fifteen to thirty milligrams of Chlorprothixen.
Behavioral disorders in childhood: The
Dose is calculated based on the weight of the child according to the formula:
Dose = 0.5 - 2 mg x child weight (in kg)
On average, the recommended dosage is:

• when nervosa - 5-30 mg per day;
• at psychoses - 100 - 200 mg for a day.

To increase the effectiveness of pain medication:
In joint treatment, along with analgesic medicines should be used from fifteen to three hundred milligrams per day.
Skin of the skin (regardless of the cause):
Having broken the daily up to four doses, eat from fifteen to one hundred milligrams per day.
Risk of abortion, premature birth:
Fifteen milligrams two - three times per knock for two to three days. Then within seven to ten days you need to use a reduced dose of medication.
In the form of Chlorprotixen injection, the treating doctor can prescribe either at the beginning of the treatment or there is a patient who can not (or refuses) to take the pills.

[27], [28], [29], [30]

Use of the chloroprotxene during pregnancy

The medication can be used in treatment during gestation and lactation, only if the expected effect from it for the mother significantly exceeds the risk for the child.

Contraindications

Chloprotoxen can not be used in the following cases:

• Individual hypersensitivity to this medication;
• Acute poisoning with substances that depress the central nervous system (including alcoholic beverages);
• Comatose state;
• Vascular collapse;
• Pheochromocytoma
• Pathologies in the hematopoiesis system;
• Periods of gestation;
• Breastfeeding the baby;
• Children up to six years.

[19]

Side effects of the chloroprotxene

The patient who consumes Chlorprothixen should know about the proportion of the likelihood of such undesirable drug manifestations appearing:

• Rapid heartbeat (tachycardia);
• Low blood pressure (hypotension);
• Dryness in the oral cavity;
• Extrapyramidal disorders.

[20], [21], [22], [23], [24], [25], [26]

Overdose

If the patient significantly exceeds the recommended dosage of the medication - he may have the following symptoms: convulsions, hypotension, shock, coma, increased excitability, uncontrolled motor activity, increased frequency of contractions of the heart muscle, impaired respiratory function.
To save the patient, he needs to immediately rinse the stomach, give medicines with laxative effect or adsorbents. In parallel, depending on the severity of the symptoms, it is worthwhile to carry out activities to maintain the patient's health. Hemodialysis in this case will not have an effect.
If the patient has cardiovascular symptoms, he should not be given Adrenaline at all, since this will greatly reduce the pressure.
Cramps are removed with the help of Diazepam.
With uncontrolled movements, you need to use Bioperiden.
Because of the likelihood of vomiting in the respiratory tract, the patient should not be vomited.

[31], [32], [33], [34]

Interactions with other drugs

If Chlorprothixene is used in conjunction with anesthetics, narcotic analgesics, soothing, neuroleptics, alcohol-containing substances - to intensify the oppressive effect of the drug.
With anticholinergic, antiallergic and anti-Parkinson's drugs - an increase in the anticholinergic effect.
Drugs that reduce blood pressure increase their effectiveness in a single dose with Chlorprothixen.
Epinephine in a joint admission leads to a decrease in blood pressure and an increase in heart rate.

[35], [36]

Storage conditions

Chlorproticineson refers to potent medicines. It must be stored in a dark, cool place. Ensure that children do not have access to it.

[37]

Shelf life

If all the conditions for storing the medicament are met, it can be used for two years.

[38]

Reviews

If you analyze all the reviews in the information space about this drug, you can say with certainty that Chlorprothixen is an excellent sleeping pill. But with regard to its effectiveness in psychoses, opinions differ: some patients believe that this drug (if the manufacturer Zentiva) copes well with its task, and others (the main number of patients) - believe that Chlorprothixen is not suitable for treating this pathology. If, however, to sum up absolutely all opinions, we can confidently say that this drug has an excellent hypnotic effect, which helps with psychoses.
Of the complaints of patients in general can be identified - increased drowsiness and a slight inhibition. It is worth noting that there are also people who, after using this medication, expressed concern and even hallucinations. Most of the reviews are positive.
Doctors mark the drug as an excellent neuroleptic, but with strict indications for use. Chlorprotixen in any case can not be combined with alcohol.