Treatment of rheumatoid arthritis with antibiotics

Rheumatoid arthritis is a fairly common disease associated with the pathology of the joints. Due to the development of the disease, inflammation of the tissues, degeneration and various complications are observed. Rheumatoid arthritis is sometimes associated with the presence of bacterial pathogens. For this reason, in some cases of development of pathology, it is not enough to use drugs whose pharmacological action is aimed at analgesia and elimination of edema and inflammatory process. Antibiotics for rheumatoid arthritis are taken to effectively influence the causative agent of the disease, but in most cases this form of the disease has no need for treatment in this way - bacteria that multiply in the joint tissues contribute to the cessation of the disease. Thus, the indications for the use of these drugs should be clearly established.

Indications of the antibiotics for rheumatoid arthritis

Treatment of rheumatoid arthritis with antibiotics occurs strictly for certain indications. Indications for the use of antibiotics in rheumatoid arthritis are as follows:

• Purulent form of the disease. To recognize the presence of pus in the joint can be on some grounds, such as:
  • hyperemia of acute type;
  • severe swelling;
  • bright reddening of the skin in the area of the inflamed joint;
  • more pronounced pain.
• Prevention of the disease in the case of frequent and long-term infectious diseases
• Prevention of the disease in case of exacerbation of diseases associated with tissue inflammation:
  • pyelonephritis;
  • bronchitis;
  • sinusitis;
  • tonsillitis;
  • and others.
• Immunodeficiency, which developed as a side effect after taking pharmacological drugs. When immunodeficiency can develop a disruption of the intestine, which is also an indication for the reception of antibacterial agents.

[1], [2], [3]

Release form

Patients seeking a "super-antibiotic" from rheumatoid arthritis should take into account the doctor's testimony and the form of the disease. Treatment of rheumatoid arthritis with antibiotics of the new generation is possible strictly according to indications, namely, with suppuration in the joint, for prevention in the presence of other inflammatory or infectious diseases and with immunodeficiency. If necessary, a specialist can prescribe an antibiotic for exacerbation of rheumatoid arthritis.

Environments of effective medicinal antibacterial agents release "Minocycline" ("Minocin", "Minolexin") - an antibacterial agent of a tetracycline series of semi-synthetic origin that is able to effectively influence the causative agents of the disease in the initial stage. After use, the swelling, pain sensations and the ability to less constrained move appear.

The form of the drug - tablets, capsules and suspension.

[4], [5], [6]

Pharmacodynamics

Pharmacodynamics and pharmacokinetics are caused by the action of the active substance - minocycline hydrochloride. Antibacterial agent "Minocycline" is able to have a bacteriostatic effect.

[7], [8], [9], [10]

Dosing and administration

The method of administration and dose for rheumatoid arthritis for adult patients is 100 milligrams twice a day. It is important not to stop treatment within 1-2 days after the normalization of the condition.

[18], [19], [20], [21]

Contraindications

The main contraindication is the individual intolerance of the components of the antibacterial substance.

It is forbidden to use antibiotics in the presence of an inflammatory form of the disease, which has no connection with the infectious form, and also when there is no indication for antibiotic therapy. In the case of a normal course of the disease, the immune system is able to cope with self-therapy.

Contraindications - age to 8 years, increased sensitivity to tetracycline antibiotics in general and minotcin in particular, kidney and liver diseases, leukopenia, porphyria, systemic lupus erythematosus, lactase insufficiency and lactose intolerance. Use during pregnancy and lactation of this drug is prohibited.

[11], [12], [13], [14]

Side effects of the antibiotics for rheumatoid arthritis

Side effects are possible in the form of impaired appetite, including anorexia, nausea and vomiting, gastrointestinal disturbances, diarrhea, skin rashes, excessive skin pigmentation due to sunlight in the form of sunburn or its discoloration, urticaria, occasionally there is anaphylactic shock, cephalgia and sensation circling in the head.

[15], [16], [17]

Overdose

Overdose is fraught with cephalalgia and vomiting. In case of overdose, further use of the drug should be avoided and the symptoms treated.

[22], [23], [24], [25], [26], [27]

Interactions with other drugs

It is not desirable to use simultaneously with hepatotoxic medicines. It is forbidden to combine the drug with the antibiotics of the penicillin group, alcohol. Isotretinoin is able to increase intracranial pressure when used concomitantly with Minocycline. The effectiveness of treatment is reduced when using this antibiotic and oral contraceptives.

[28], [29], [30], [31], [32], [33]

Storage conditions

It is important to observe the storage conditions (out of reach for children, with a temperature regime of no higher than 25 degrees and with a minimum amount of moisture) and shelf life (2 years).

[34], [35], [36], [37], [38], [39], [40]

Antibiotics for rheumatoid arthritis should be taken only with clear indications of a specialist in order to avoid complications and consequences.