Treatment of rheumatoid arthritis with antibiotics

Rheumatoid arthritis is a fairly common disease associated with joint pathology. As a result of the disease, tissue inflammation, degeneration and various complications are observed. Rheumatoid arthritis is sometimes associated with the presence of bacterial pathogens. For this reason, in some cases of pathology, it is not enough to use drugs whose pharmacological action is aimed at analgesia and the elimination of swelling and inflammation. Antibiotics for rheumatoid arthritis are taken to effectively affect the causative agent of the disease, but in most cases this form of the disease does not need treatment with this method - bacteria multiplying in the joint tissues help stop the disease. Thus, it is necessary to clearly establish the indications for the use of these drugs.

Indications antibiotics for rheumatoid arthritis.

Treatment of rheumatoid arthritis with antibiotics occurs strictly according to certain indications. Indications for the use of antibiotics for rheumatoid arthritis are as follows:

• Purulent form of the disease. The presence of pus in the joint can be recognized by some signs, such as:
  • acute hyperemia;
  • severe swelling;
  • bright redness of the skin in the area of the inflamed joint;
  • more pronounced pain sensations.
• Prevention of disease in case of frequent and long-term infectious diseases
• Prevention of disease in case of exacerbation of diseases associated with tissue inflammation:
  • pyelonephritis;
  • bronchitis;
  • sinusitis;
  • tonsillitis;
  • and others.
• Immunodeficiency that developed as a side effect after taking pharmacological drugs. With immunodeficiency, intestinal dysfunction may develop, which is also an indication for taking antibacterial agents.

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Release form

Patients looking for a “super-antibiotic” for rheumatoid arthritis should take into account the doctor’s indications and the form of the disease. Treatment of rheumatoid arthritis with new-generation antibiotics is possible strictly according to indications, namely, in case of suppuration in the joint, for prevention in the presence of other inflammatory or infectious diseases and in case of immunodeficiency. If necessary, a specialist can prescribe an antibiotic for an exacerbation of rheumatoid arthritis.

Among the effective medicinal antibacterial agents, “Minocycline” (“Minocin”, “Minolexin”) is distinguished - an antibacterial agent of the tetracycline series of semi-synthetic origin, which is able to effectively affect the pathogens of the disease at the initial stage. After use, swelling and pain sensations are reduced and the ability to move less constrained appears.

The drug is available in the form of tablets, capsules and suspension.

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Pharmacodynamics

Pharmacodynamics and pharmacokinetics are determined by the action of the active substance - minocycline hydrochloride. The antibacterial agent "Minocycline" is capable of exerting a bacteriostatic effect.

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Dosing and administration

The method of administration and dosage for rheumatoid arthritis for adult patients is 100 milligrams twice a day. It is important not to stop treatment for 1-2 days after the condition has returned to normal.

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Contraindications

The main contraindication is individual intolerance to the components of the antibacterial substance.

The use of antibiotics is prohibited in the presence of an inflammatory form of the disease that is not related to the infectious form, as well as in cases where there are no indications for antibacterial therapy. In the case of a normal course of the disease, the immune system is able to cope with self-therapy.

Contraindications - age under 8 years, hypersensitivity to tetracycline antibiotics in general and minocin in particular, kidney and liver diseases, leukopenia, porphyria, systemic lupus erythematosus, lactase deficiency and lactose intolerance. Use during pregnancy and lactation of this drug is prohibited.

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Side effects antibiotics for rheumatoid arthritis.

Side effects may include loss of appetite, including anorexia, nausea and vomiting, gastrointestinal upset, diarrhea, skin rash, excessive skin pigmentation due to exposure to sunlight in the form of tanning or discoloration, urticaria, and occasionally anaphylactic shock, headache and dizziness.

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Overdose

Overdose may cause headache and vomiting. In case of overdose, further use of the drug should be stopped and symptoms should be treated.

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Interactions with other drugs

It is not advisable to use it simultaneously with hepatotoxic medications. It is forbidden to combine the drug with antibiotics of the penicillin group, alcohol. Isotretinoin can increase intracranial pressure when used simultaneously with Minocycline. The effectiveness of treatment is reduced when using this antibiotic and oral contraceptives.

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Storage conditions

It is important to observe storage conditions (out of reach of children, at a temperature not exceeding 25 degrees and with a minimum amount of moisture) and shelf life (2 years).

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Antibiotics for rheumatoid arthritis should be taken only under clear instructions from a specialist to avoid complications and consequences.