Tempalgin

Tempalgin has analgesic, anti-inflammatory, anxiolytic and antipyretic effects.

Indications Tempalgina

Applicable in the following cases:

• painful sensations having a different nature - headaches or dental pains, but also neuralgia with myalgia or migraine ;
• pain visceral type - for example, in the intestines or kidneys, and in addition liver cramps;
• weakening of mild pain that occurs after surgical procedures or diagnostic tests.

Release form

The release is carried out in a tablet form, 10 pieces inside blister packs. The box contains 2, 10 or 30 such packages.

Pharmacodynamics

The medication has sedative and analgesic properties, and its therapeutic effect is due to the components that make up its composition.

Metamizole sodium has a moderate anti-inflammatory effect and analgesic effect. These properties are provided by slowing down the elements of COX-1 and COX-2.

Tempidon helps to eliminate anxiety and get rid of feelings of fear, and besides it helps to ease motor excitement and slightly reduce blood pressure.

Both of these components can enhance the drug efficacy of each other.

Pharmacokinetics

The medicine at high speed is absorbed, getting inside the digestive tract. Medicamental activity is noted after the expiration of half an hour, and the peak values of the active elements inside the blood are recorded after a lapse of 1-2 hours. Metabolism of drugs occurs inside the liver.

Excretion of the drug occurs in the form of metabolic products, as well as a small part of the unchanged component - together with urine, as well as bile.

Dosing and administration

Use the medication orally, after eating, squeezed while drinking plenty of plain water. The size of the dosage portion of the drug depends on the degree of pain intensity, as well as the individual characteristics of the patient.

For an adult, the 1st pill is often prescribed 1-3 times a day. The size of the maximum allowable single dose - 1 tablet, and the daily - a maximum of 4 tablets. When carrying out dental procedures, it is necessary to use 1 tablet 30 minutes before the procedure.

Adolescents over 15 years of age are allowed to consume a maximum of 2 tablets per day.

The duration of the treatment course can be a maximum of 3-5 days. If application is required in terms exceeding this period, it is necessary to consult this account with the doctor.

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Use Tempalgina during pregnancy

Do not use Tempalgin during pregnancy or during lactation.

Contraindications

Among the contraindications:

• decreased values of blood pressure;
• deficiency of G6FD element inside the body;
• Insufficiency of renal / hepatic activity in severe degree;
• disorder of blood-forming processes;
• aspirin asthma;
• the presence of intolerance with respect to the elements of the drug.

Side effects Tempalgina

The use of medication can cause the emergence of certain side-effects:

• dizziness along with headaches, as well as hallucinations;
• development of cholestasis, hyperbilirubinemia, jaundice or hyperfermentemia;
• vomiting, epigastric pain and nausea;
• pressure leaps, leuko- or thrombocytopenia, agranulocytosis, tachycardia, and in addition oliguria, cyanosis, proteinuria, and so on.

At the same time, it is possible to expect the appearance of allergy signs, including skin itching, hives, exudative erythema, anaphylaxis, angioedema and bronchial spasms.

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Overdose

In case of an overdose, it is possible to develop a variety of negative manifestations that have a different degree of severity. When poisoning can develop vomiting, dyspnea, a decrease in blood pressure, tachycardia, severe pain in the abdominal area, a feeling of drowsiness, convulsions and frustration. In addition, there may be kidney / liver failure.

To eliminate violations apply therapy in the form of gastric lavage, reception of enterosorbents, as well as other symptomatic procedures. In more severe forms of disorders, hemodialysis or forced diuresis are used.

Interactions with other drugs

Combination of the drug with phenothiazine derivatives leads to the appearance of hyperthermia. Combination with sedatives and tranquilizers can potentiate the analgesic effect of drugs.

The risk of leukopenia increases with a combination of medication with thiamazole or cytostatics.

Tempalgin is able to reduce plasma cyclosporine levels, and in addition to increase the drug effect of antidiabetics, GCS, indomethacin and anticoagulants with an indirect type of influence.

When combined, the activity of inductor preparations of liver enzymes, such as barbiturates or phenylbutazone, can be reduced.

It is impossible to exclude mutual potentiation of toxic properties when the drug is combined with NSAIDs, allopurinol, metamizole sodium, individual oral contraceptives and tricyclics.

Codeine with propranolol, as well as drugs that block the activity of H2-terminus, can inhibit the elimination of Tempalgine.

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Storage conditions

Tempalgin is required to be kept in a dark place, protected from penetration of moisture and access of young children. The medication should be stored at elevations below 25 ° C.

Shelf life

Tempalgin is allowed to be used within 4 years of the release of the therapeutic agent.

Application for children

The medicine can not be administered to children.

Analogues

Analogues of the drug are drugs Cardiomagnesium, Tantum Verde, as well as Tempanginol with Amizone and Paracetamol.

Reviews

Tempalgin receives a large number of reviews, many of which indicate that he demonstrates a fairly high efficiency. The medication helps to eliminate the pain that occurs during menstruation, as well as headaches and toothaches.

It should be noted immediately that the drug has different effects on different people. For example, in some of them, in addition to eliminating pain, it also reduces or increases blood pressure, and some patients did not notice any medication at all. Usually the reason for this is not the degree of pain, but the pathogenic factors that provoke their development.

There are reports that indicate that some patients have used the drug for a long time as an analgesic. There are also data when patients, taking Tempalgin, weakened the severity of pain, resulting in the disease passing into a chronic stage of development.

Of course, there are situations in which the use of analgesic drugs is extremely necessary, but it must be understood that in the absence of a result of the use of drugs it is necessary to contact the doctor without self-medication.