Medical expert of the article
New publications
Preparations
Tantum verde
Last reviewed: 03.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
The pharmaceutical product Tantum Verde is a representative of pain-relieving and anti-inflammatory non-steroidal drugs that are prescribed in dental and otolaryngological practice.
Indications Tantum verde
Tantum Verde can be used as a symptomatic or prophylactic medication for the following painful conditions:
- inflammation in the oral cavity (stomatitis, inflammation of the tongue or gums);
- postoperative period in dentistry;
- acute pharyngitis or tonsillitis;
- candidal stomatitis;
- angina;
- periodontal inflammation;
- ulcers, erosions, mechanical damage to the mucous tissues of the oral cavity.
Release form
Tantum Verde can be produced in a variety of medicinal forms:
- Tantum Verde lozenges, which need to be dissolved in the cheek (the cardboard box contains two blister packs with 10 tablets in each pack);
- Tantum Verde liquid for external use and rinsing (a 120 ml glass bottle contains a greenish solution with a mint aroma);
- Tantum Verde aerosol spray for spraying (30 ml plastic bottle with a dosing pump device and a greenish solution with a mint aroma).
The active ingredient of Tantum Verde is benzydamine hydrochloride.
[ 3 ]
Pharmacodynamics
The active component benzydamine hydrochloride belongs to the category of non-steroidal anti-inflammatory drugs with analgesic and antiexudative effects.
Studies have shown that Tantum Verde has a pronounced effect in eliminating painful symptoms that occur during the inflammatory process in the oropharynx. Tantum Verde stops the development of the inflammatory process, relieves pain locally.
Pharmacokinetics
The effect of absorption of Tantum Verde components through the mucous tissues of the oral cavity and oropharynx was determined by measuring the level of benzydamine in the blood serum of patients. Approximately two hours after application of Tantum Verde, the maximum content of the drug in the blood serum was 37.8 ng / ml, and the AUC value was 367 ng / ml per hour.
However, these values are considered to be insignificant for the systemic effects of the drug.
Excretion occurs primarily with urine – in the form of inactive metabolic products or conjugates.
It was determined that external use of Tantum Verde leads to accumulation of the active component in the inflamed tissue layers. This allows achieving a therapeutically optimal amount of the drug.
Dosing and administration
- Tantum Verde lozenges are held in the cheek until completely dissolved, 1 piece up to four times a day.
- The liquid medicine Tantum Verde is used in the amount of one tablespoon (15 ml) for rinsing and irrigation of the mucous membrane. Frequency of use - every 2-3 hours. Do not swallow the external medicine!
- Spray Tantum Verde in the amount of 4-8 injections every 2-3 hours. In children from six to twelve years old, use 4 injections four times a day.
The duration of therapy with Tantum Verde is determined individually by the doctor.
Use Tantum verde during pregnancy
To date, there is insufficient data on the possibility of taking Tantum Verde during pregnancy and breastfeeding.
The possibility of the active ingredient Tantum Verde entering breast milk has not been studied.
There is information about testing the drug on experimental animals, but this information is extremely insufficient.
Considering the above, experts do not recommend treatment with Tantum Verde for pregnant and lactating patients.
Contraindications
It is not recommended to prescribe any medicinal form of Tantum Verde:
- throughout the entire period of pregnancy and breastfeeding;
- pediatric patients (up to 6 years old);
- with phenylketonuria;
- if you are prone to allergic reactions to the composition of the drug.
[ 4 ]
Side effects Tantum verde
Local application of Tantum Verde may be accompanied by the following side effects:
- burning sensation in the mouth, thirst;
- allergy;
- phenomena of laryngospasm;
- development of photosensitivity of the skin and mucous membranes.
It is worth noting that side effects occur very rarely and disappear after stopping the use of the drug.
[ 5 ]
Overdose
At present, there have been no registered cases of overdose of Tantum Verde when applied externally.
There is information that the active ingredient of Tantum Verde when taken orally in large doses (100 times the recommended dosage) can provoke a state of overexcitation, convulsions, tremors in the limbs, dyspepsia, hyperhidrosis, ataxia. In such a situation, immediate gastric lavage, restorative correction of water-electrolyte balance, symptomatic therapy are recommended.
Storage conditions
Tantum Verde can be stored in dry places, at temperatures from +15°C to +25°C. It is better to store the medicine in its original packaging, out of reach of children.
[ 12 ]
Attention!
To simplify the perception of information, this instruction for use of the drug "Tantum verde" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.