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Pills for hot flashes at menopause: hormonal and non-hormonal
Last reviewed: 03.07.2025

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Hot flashes during menopause are a fairly common symptom that can make adjustments to a woman’s daily life.
Indications for menopausal hot flashes.
Pills for hot flashes during menopause are used immediately as soon as the first symptoms appear: a sudden feeling of heat, which can also quickly go away, a slight increase in body temperature, discomfort and pain in the chest area, general weakness, increased sweating, redness of the skin (especially on the face). Despite the fact that hot flashes usually last no more than a minute, they can cause a lot of trouble for women. Therefore, doctors recommend using special pills.
Release form
First of all, it is necessary to pay attention that different types of drugs are used to improve the condition of women during hot flashes, but the most popular among them are non-hormonal drugs, antidepressants and antiepileptic drugs. Today, the following pills for hot flashes can be distinguished, which help women at any age feel great:
- Estrovel.
- Klimadinon Uno.
- Klimadinon.
- Feminal.
- Femicaps Easy Life.
- Femiwell.
- Qi-Klim.
- Lady's Formula "Menopause".
- Menopace.
- Klimaktoplan.
- Klimaxan.
- Klimakt-Hel.
- Lefem.
- Klimalanin.
- Ovariamin.
- Inoclim.
- Epifamin.
- Ephevelon.
- Velaxin.
- Velafax.
- Gabagamma.
- Katena.
- Convalis.
- Neurontin.
- Tebantin.
Let's take a closer look at them.
Non-hormonal pills for hot flashes during menopause
The most popular non-hormonal medications used during menopause to treat hot flashes are phytoestrogens. They are homeopathic remedies or dietary supplements, so they do not cause allergies or other unpleasant side effects. Most non-hormonal pills are distinguished by the fact that they consist of substances that are very close to natural female hormones in their structure. These are the hormones that the female body most often lacks after menopause.
Estrovel
A medicine based on the active components of black cohosh, wild yam, isoflavones, indole-3 carbinol, nettle, vitamins (E, B), folic acid, natural amino acids. Due to this composition, the drug allows you to improve your condition in a matter of days, regulate the work of the autonomic nervous system, reduce heartbeat, relieve dizziness, eliminate pain, compensate for those hormones that are deficient, increase the body's immunity, and reduce the number of hot flashes.
It is recommended to take Estrovel tablets during meals, one capsule no more than twice per 24 hours. The therapy continues for about two months to achieve a positive result. If the patient does not feel any improvement, the dosage can be increased to three or even four tablets.
It is not recommended for patients with phenylketonuria or allergies to the components of the tablets. It may cause burning, irritation, urticaria.
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Klimadinon Uno
A medicine based on the active component of the extract from the rhizome of black cohosh (dry). A herbal remedy that is used to reduce the number of hot flashes. It has an estrogen-like effect.
It is recommended to take Klimadinon Uno tablets one capsule at a time no more than once every 24 hours. It is advisable to always take the drug at the same time. Wash down with water in small quantities. Therapy lasts about three months to achieve a positive result, but its duration can be increased on the recommendation of a doctor.
It is not recommended to use the product for patients with estrogen-dependent tumors, as well as allergic reactions to the components that are part of the tablets. It can cause discomfort in the abdominal area.
Klimadinon
A medicine based on the active component of dry extract from the rhizome of black cohosh. A herbal remedy that helps reduce the manifestations of climatic syndrome, reduce the number of hot flashes and their strength, and have a positive effect on the autonomic nervous system.
It is recommended to take Klimadinon tablets one capsule no more than twice per 24 hours. It is best to take the drug at the same time (usually in the morning and evening). The duration of therapy is determined by the doctor, who, if necessary, can also increase the dosage.
Klimadinon tablets are not recommended for patients with estrogen-dependent tumors, as well as with allergic reactions to the drug component. Do not use to treat alcohol-dependent patients. May cause abdominal pain, allergies, bleeding.
Feminal
A medicine based on the active component of dry extract from red clover. It is a herbal preparation, which is considered a source of isoflavones, which help maintain women's health. It is recommended to take these tablets at the onset of the first symptoms of menopause.
It is recommended to take Feminal tablets one capsule no more than once every 24 hours during meals. Since this drug is a dietary supplement, it can be used for a long time, but before use, be sure to consult your doctor.
May cause allergic reactions.
Femicaps Easy Life
A medicine based on active components of the extract from the fruits of sacred Vitex, evening primrose oil, passion flower extract, magnesium oxide, vitamin E, pyridoxine hydrochloride, soy lecithin and wax. Thanks to this composition, the drug helps to cope with the main symptoms of menopause in a short time, including hot flashes.
It is recommended to take Femicaps Easy Life tablets two capsules no more than twice per 24 hours. It is best to drink them after meals, with water. The recommended course of administration lasts about three months to achieve a positive result.
It is not recommended to take tablets for patients with allergies to the components of the herbal remedy. It may cause urticaria.
Femiwell
A medicine based on the active components of soy protein, red clover extract and vitamin E. It is actively used to treat symptoms that occur in women with the onset of menopause. With regular use of Femivell tablets, women noticeably reduce the number and strength of hot flashes.
Doctors recommend taking Femivell tablets one capsule no more than once every 24 hours for two months to achieve an effective result. After completing the therapy, it is necessary to consult with the attending physician, who can prescribe a course of the drug again.
May cause allergies, so people who are prone to allergic reactions should take it with caution.
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Qi-Klim
A medicine based on the active component of the extract from black cohosh (in dry form). Due to this, the herbal preparation has an estrogen-like effect, helps improve the functioning of the autonomic system, reduce the number of hot flashes and their strength.
It is recommended to take Qi-Klim tablets one capsule no more than twice per 24 hours. Do not chew the tablet, but wash it down with water (a small amount). It is important to take it at the same hour (if possible). The duration is determined by the doctor.
It may cause allergic reactions, so Qi-Klim tablets should be taken with caution.
Lady's Formula "Menopause"
A medicine based on the active components of boron, chromium, manganese, pantothenic acid, nicotinic acid, vitamin E, angelica and spirulina. Due to this composition, this herbal remedy is considered very effective in combating the main symptoms of menopause, including hot flashes. It is recommended for women who have strong hot flashes.
It is recommended to take Menopause tablets one capsule at a time no more than once every 24 hours. To achieve a positive result, you need to take the drug for at least one month. In some cases, the doctor may recommend a higher dosage or duration of the course.
You should not take Menopause tablets together with vitamin complexes. If you suffer from frequent allergies, you should take the product with caution, as it can cause allergic reactions.
Menopace
A medicine based on active components of the vitamin complex (A, B, E, D), biotin, folic acid, nicotinamide, iron, pantothenic acid, para-aminobenzoic acid, selenium, chromium, bromine, manganese, copper, iodine, selenium. Thanks to such a set of vitamins and minerals, a woman receives all the necessary microelements during menopause. This helps to improve well-being and relieve the main symptoms of menopause.
It is recommended to take Menopace tablets one capsule at a time no more than once every 24 hours. For the drug to be better absorbed, it is necessary to drink it after meals, with plain water. Do not chew. The duration of therapy is determined by the doctor individually.
You should not take Menopace tablets if you have an allergy to the components of the drug, various hypervitaminosis, kidney dysfunction, hemochromatosis, nephrolithiasis, hemosiderosis, urolithiasis, phenylketonuria. Taking tablets can cause nausea, diarrhea, urticaria, and yellowish urine.
Klimaktoplan
Homeopathic medicine based on the active components Sanguinaria, Lachesis, Cimicifuga, Ignatia, Sepia. The drug binds to estrogen receptors, due to which it has an estrogen-like effect. Helps to normalize sleep, emotions, works as a sedative.
It is recommended to drink Klimaktoplan one capsule no more than three times per 24 hours. For best results, take the tablets a few minutes before meals. Do not swallow the capsules, but slowly dissolve them in your mouth.
Doctors recommend that people with allergies to the components of the drug take Klimaktoplan tablets with caution.
Klimaxan
A medicine based on the active components of black cohosh, lyachesis and apis. Helps relieve the main symptoms of menopause, including hot flashes.
It is recommended to take Klimaxan tablets one capsule no more than twice in 24 hours. It is best to take at the same time every day (if possible, in the morning and evening). Tablets should not be swallowed or chewed, they should be dissolved in the mouth. The duration of the course is individual, but cannot exceed two months.
Do not use for children or patients with allergies to the main components of the product. May cause various allergic reactions, including urticaria, but is generally well tolerated.
Klimakt-Hel
A medicine based on the active components of Sanguinaria, Sepia, Strychnos Ignatia, Sulfur, Lachesis Mutus, Simarouba Cedron, Stannum Metallicum. Very often prescribed by doctors to relieve the main symptoms of hot flashes.
It is recommended to take Klimakt-Hel tablets one capsule no more than three times in 24 hours. In order for the active components to be better absorbed by the body, it is necessary to drink the drug before meals (thirty minutes) or after meals (one hour). Keep the capsule in the mouth until it completely melts. The duration of the course is individual, but cannot be more than three months.
Women should not take Klimakt-Hel if they have allergic reactions to its components. It may cause the development of allergies or (very rarely) drug-induced toxic hepatitis.
Lefem
A medicine based on the active component of soybean seed extract. Due to this, the product is a source of estrogens, the amount of which decreases during menopause. It helps reduce the frequency and strength of hot flashes, as well as relieve other symptoms of menopause.
It is recommended to take Lefem tablets one or two capsules no more than twice per 24 hours. Since the drug must be taken for a long period of time, to see truly positive results, the therapy continues for about a year. In case of complications, the doctor may recommend taking tablets even up to three years.
It is not recommended to take Lefem tablets for those who suffer from frequent allergic reactions. Taking it can cause allergies, including urticaria.
Klimalanin
A medicine based on the active component β-alanine, which inhibits the too rapid release of histamine. This reduces the strength and frequency of hot flashes, as well as significantly improves a woman's well-being during menopause.
It is recommended to take Klimalanin tablets no more than two capsules in 24 hours. If the patient's health has not improved, the attending physician may advise taking three capsules. The therapy lasts no more than ten days. During this time, all symptoms of hot flashes should completely disappear. When the signs appear again, it is recommended to repeat the entire course.
The drug is completely safe, does not cause side effects and has no contraindications.
Ovariamin
A medicine based on a whole complex of nucleotides and proteins obtained from cow ovaries. Thanks to this composition, the product helps to quickly normalize the functioning of the vegetative and reproductive systems of women after menopause.
Take no more than three capsules in 24 hours as recommended by your doctor (the dose should be divided into three times). Drink before meals (at least 15 minutes). The therapy lasts no more than fifteen days, but to consolidate the effect, another course should be taken after six months.
No side effects from taking Ovariamin tablets have been identified. The drug has no contraindications, so you can take it without worrying about your health.
Inoklim
A medicine based on active components: soybean oil, sunflower oil, glycerin, fish gelatin, soybean extract, soy lecithin, titanium dioxide, corn starch, iron red oxide. Due to this composition, the drug has an estrogen-like effect.
Inoklim tablets are recommended to be taken one capsule at a time for three months to achieve a positive result. If there is no improvement, over time the attending physician may recommend drinking two capsules in 24 hours. The course is repeated if necessary.
This product has no contraindications, but it can cause allergic reactions.
Epiphamin
A medicine based on the active component epifamin in powder form. Epifamin is a complex of nucleic acids and polypeptides that are extracted from the pineal gland of pigs and cows. Due to this, the product has a positive effect on the well-being of women during menopause.
It is recommended to take Epifamin tablets no more than three capsules two or three times in 24 hours. Take before meals (at least fifteen minutes). Do not chew. Therapy lasts about two weeks. But if necessary, the doctor may prescribe a repeat course.
May cause allergic reactions.
Antidepressants
During menopause, against the background of constant hot flashes, many women develop various types of depressive disorders (involutional, climacteric, psychogenic and endogenous depression). Previously, hormone replacement therapy was used to treat all the symptoms of menopause, but later it turned out that it can significantly worsen the emotional state of the patient. Therefore, antidepressants have become indispensable drugs that can quite gently and quickly help cope with the symptoms of depression.
Antidepressants are psychotropic drugs that are primarily prescribed for depression. They can improve mood, improve well-being, and relieve feelings of melancholy and uselessness. Such drugs should not be taken independently, only on the recommendation of a doctor, as they are quite serious drugs.
Ephevelon
A medicine based on the active ingredient venlafaxine hydrochloride. An antidepressant that is often prescribed to women during menopause to relieve the main symptoms of depression.
It is recommended to take Efevelon tablets of 75 mg, dividing this dose into two times. It is very important to take the drug every day at the same time. A more detailed dosage is always prescribed by the attending physician.
Do not take Efevelon tablets together with other MAO inhibitors, if you have kidney or liver problems. It may cause weakness, loss of appetite, dry mouth, weight loss, hypertension, abnormal dreams, manic attacks, accommodation disorders, dysuria, erectile dysfunction, increased sweating, allergic reactions.
Velaxin
A medicine based on the active component venlafaxine. It is used to treat various types of depression that occur in women during menopause.
Velaxin tablets can be taken only on the recommendation of a doctor and only during meals. The initial dose is 75 mg of the drug, which should be divided into two doses. If the patient does not improve after several weeks of such treatment, the dose can be increased to 150 mg twice in 24 hours.
It is not recommended to take Velaxin tablets for patients with impaired liver and kidney function, together with MAO inhibitors. Taking tablets can cause constipation, drowsiness, skin hyperemia, dizziness, insomnia, apathy, hallucinations, dysuria, mydriasis, photosensitivity, allergies.
Velafax
A medicine based on the active ingredient venlafaxine hydrochloride. An antidepressant that is widely used to treat depression that occurs during menopause.
The recommended starting dose of Velafax tablets is as follows: 37.5 mg of the drug is taken daily before meals with plenty of liquid. The dose should be divided into two doses. If the patient's condition does not improve, the attending physician may increase the dosage.
You should not take Velafax tablets together with MAO inhibitors, or in case of renal or hepatic insufficiency.
May cause loss of appetite, dizziness, headaches, manic attacks, insomnia, nightmares, constipation, nausea, skin hyperemia, fainting, asthenia, tremors, yawning, allergic reactions.
Antiepileptic drugs
During menopause, to reduce the strength and frequency of hot flashes, as well as to improve the general condition of the woman, doctors prescribe various antiepileptic tablets. The most popular among them are: Gabagamma, Tebantin, Catena, Neurontin, Convalis. It should be remembered that such drugs are quite serious drugs, so they are not recommended for use without a specialist's prescription.
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Gabagamma
A medicine based on the active ingredient hebapentin. An anticonvulsant drug, which, however, helps to significantly reduce the intensity of hot flashes during menopause.
It is recommended to take Gabagamma tablets in a dosage of 900 mg, which is divided into three times. It can be taken regardless of food. If it is necessary to stop taking the drug or reduce the dose, it should be done gradually, over the course of one week.
Gabagamma tablets should not be taken by patients with acute pancreatitis, galactose or glucose malabsorption syndrome, lactose deficiency, lactose insufficiency, mental illness. Taking Gabagamma tablets may cause pneumonia, frequent viral diseases, thrombocytopenia, emotional lability, hostility, headaches, drowsiness, tremor, dizziness, decreased vision, tinnitus, arterial hypertension, allergies.
Catena
A medicine based on the active component hebapentin. An anticonvulsant that, in some cases, helps improve the condition of women during hot flashes and regulate their arrival.
Katena tablets are taken regardless of food, 900 mg each. The dose should be divided into three separate doses. If there is a need to reduce the dosage or stop taking Katena tablets, it is recommended to do this gradually (over the course of one week). The duration of administration is determined by the attending physician.
Patients with impaired renal function should take the tablets with caution and under the supervision of a specialist. May cause symptoms of hypertension and vasodilation, increased appetite, myalgia, rhinitis, bronchitis, impaired thinking, leukopenia, amblyopia, allergic reactions, and increase bone fragility.
Convalis
A medicine based on the active ingredient hebapentin. The drug is often prescribed as a treatment for hot flashes during menopause.
It is recommended to take Convalis tablets once every 24 hours at 300 mg. This is the initial dose, which is gradually increased to 900 mg, which are divided into three doses. Wash down with a sufficient amount of water, regardless of food. To stop therapy, it is necessary to gradually reduce the dosage.
It is not recommended to use Convalis to treat patients with acute pancreatitis, lactose deficiency or intolerance. Taking tablets may provoke the development of amnesia, diarrhea, confusion, dizziness, shortness of breath, pharyngitis, headaches, flu-like syndromes, flatulence, abdominal pain, purpura, arthralgia, allergies.
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Neurontin
A medicine based on the active ingredient hebapentin. An anticonvulsant that is widely used to relieve the unpleasant symptoms of hot flashes during female menopause.
The dosage is determined by a specialist on an individual basis, but, as a rule, it consists of 900 mg of the drug, which should be divided into three doses in 24 hours. If it is necessary to reduce the dose or start using another drug, it is worth gradually reducing the dose (within one week). Can be taken with food.
Patients with impaired renal function should take Neurontin tablets with special caution. Taking this drug can cause asthenia, back pain, confusion, infections, dyspepsia, headaches, pharyngitis, dizziness, allergic reactions.
Tebantin
A medicine based on the active component hebapentin. Widely used to treat hot flashes that occur during menopause. Anticonvulsant.
The dosage of Tebantin tablets is as follows: 900 to 1200 mg of the drug is divided into three doses in 24 hours. The dose is increased gradually. Before use, it is necessary to consult with the attending physician.
Patients who have been diagnosed with acute pancreatitis, liver or kidney dysfunction, or lactose deficiency are not recommended to use Tebantin tablets.
May cause dizziness, insomnia, confusion, headaches, pancreatitis, toothache, flatulence, gingivitis, jaundice, dyspepsia, leukopenia, pneumonia, myalgia, rhinitis, diplopia, allergies.
Let's consider the pharmacodynamics and pharmacokinetics of tablets for menopause against hot flashes using the popular drug "Estrovel" as an example.
Pharmacodynamics
Cimicifuga, which is part of the tablets, quickly and effectively alleviates the main symptoms that appear during menopause. It has a positive effect on the functioning of the autonomic system, reduces the intensity of hot flashes, dizziness and sweating. Relieves muscle pain and headaches.
Soy isoflavones, which are also an active component of Estrovel, are plant substances that are very similar in their functions to the female hormone estrogen. That is why they reduce the number of hot flashes and their strength.
Wild yam extract helps to get rid of pathological conditions caused by imbalance of female hormones.
The extract of stinging nettle takes an active part in the creation of blood cells, restores bone tissue, and prevents the development of osteoporosis.
Indole-3-carbinol eliminates viruses and pathogenic microorganisms, normalizes hormonal balance.
Boron enhances the action of phytoestrogens.
The vitamins included in the tablets help to cope with excessive vaginal dryness, speed up protein metabolism, and reduce swelling.
Pharmacokinetics
The pharmacokinetics of Estrovel tablets have not been studied.
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Contraindications
- Kidney disease.
- Chronic and acute liver diseases.
- Acute pancreatitis.
- Frequent allergic reactions.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Pills for hot flashes at menopause: hormonal and non-hormonal" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.