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The pharmacological market offers a wide range of medicines that facilitate the process of quitting tobacco. In their fight against nicotine addiction, most smokers, even with a long record of 10-20 years, prefer the Bulgarian company Sopharma Pharmaceuticals and its drug Tabex. According to reviews, it is this remedy that most effectively suppresses cravings for smoking. The long-awaited disposal of the addictive habit is already on the fifth day of taking the medicine.

Indications Tabex

Based on consumer feedback, Tabex is considered the No. 1 drug in the fight against nicotine addiction. It works even in cases when sucking candies and plaster have not helped, including cases of an impressive length of tobacco abuse (20-30 years).

According to the instructions, indications for the use of Tabex include:

The drug helps to smoothly give up cigarettes and minimizes the manifestation of withdrawal symptoms ("withdrawal").

Release form

Pharmacological drug Tabex is available in tablet form. The form of release - round, biconcave tablets in a light brown shell.

The main component of the cytisin-alkaloid drug is the seed of the plant of the creeping roach Cytisus laburnum, which in one tablet contains 1.5 mg. Lactose monohydrate, microcrystalline cellulose, magnesium stearate and talc are auxiliary substances.

The film sheath is made of Opadry II brown, consisting of lactose monohydrate, titanium dioxide, dye, triacetin, hypromellose, macrogol 3000.


The action of Tabex is based on stimulation of brain receptors, which is akin to the effect of nicotine. However, the drug, unlike cigarettes, is not addictive, but rather provokes an aversion to tobacco smoke. The drug minimizes the possibility of relapses and disruptions, relieving a person from physical and psychological attraction to cigarettes. "Nicotine Diet" gives its fruits in the form of unpleasant sensations from the next tightening. The fact is that Tabex consists of the products of the decay of nicotine, creating the first therapeutic stage impression of the first cigarette in your life. The main advantage of the drug is that on the one hand it stimulates a person to give up cigarettes by developing negative emotions and taste perception, and on the other hand helps to relieve the stress of quitting smoking painlessly.

Tabex belongs to the group of H-holinomimetikov, excitatory acting on the nicotinic receptors of autonomous ganglia (department of the autonomic nervous system).

Pharmacodynamics Tabex is based on the reflex stimulation of the center of respiration, the release of adrenaline by the adrenal glands, namely: chromaffin cells and increased blood pressure.

Tablets reduce tobacco dependence due to the development of unpleasant sensations from cigarettes from the taste buds, causing the smoker to reject and dislike tobacco. Thus, the craving for cigarettes is reduced and the stressful state of the organism associated with the rejection of nicotine is minimized.


The pharmacokinetics of Tabex were not studied, the manufacturer did not provide any data.

Use Tabex during pregnancy

It is not recommended to use Tabex during pregnancy because of toxic embryo poisoning. Do not also use the medicine during lactation.


Contraindications to the use of Tabex:

  • myocardial infarction during exacerbation;
  • angina characterized by instability;
  • arrhythmia;
  • problems with blood circulation in the brain;
  • atherosclerosis;
  • detection of damage to large vessels;
  • arterial hypertension;
  • diagnosis of pulmonary edema;
  • stomach ulcer and 12n-intestine in the process of exacerbation;
  • bronchial asthma;
  • period of gestation and lactation;
  • individual sensitivity to the components of the drug.

The drug has limitations on the use of:

  • patients with schizophrenia;
  • patients suffering from tumors of the adrenal chromaffin type and cardiac pathology (ischemia and chronic heart failure).

Particular caution in using Tabex should be observed for smokers with vascular dysfunction in the brain, diabetes mellitus, gastroesophageal reflux, gastric peptic ulcer, in cases of renal and hepatic insufficiency.

Side effects Tabex

Speaking about the side effects of the drug, you should not forget about the harm caused by nicotine to the human body. In addition, the negative effects of taking the drug apply to a narrow group of smokers.

Side effects of Tabex on the digestive system include:

  • distortion of taste sensations from food and appetite;
  • dryness in the oral cavity;
  • soreness in the abdomen;
  • symptoms of intoxication.

Dysfunctions of the central nervous system are determined by attacks of headache, dizziness, irritability / nervousness and fatigue, drowsiness, insomnia.

The negative influence of Tabex on the cardiovascular system:

  • cardiopalmus;
  • pressure jumps;
  • tachycardia;
  • pain in the sternum;
  • the appearance of dyspnea.

Some patients report weight loss, profuse sweating, allergic manifestations, myalgia and other side effects, which in most cases pass on their own.

Tabex does not come out to give to a person without his knowledge, because to use the medicine you need control and desire on the part of the smoker himself.

The drug does not cause a change in mental activity, so it is used by smokers, whose scope requires increased attention and concentration (drivers, machinery workers, etc.).

Dosing and administration

Tablets Tabex use whole, not chewing, squeezed with a sufficient amount of water. The first three days take a pill of the drug at a two-hour interval, that is, six times a day. It is important to simultaneously reduce the number of cigarettes smoked per day. In the event that a positive action of the drug is not noted, the reception is canceled and after two or three months the attempt is repeated.

If the desired effect is achieved and the craving for tobacco is markedly reduced, then the following method of application and dose of Tabex are:



Tablets per day


1tab. Every 2.5 hours

5 pieces 


1tab. Every 3 hours

4 things


1tab. Every 5 hours

3 pcs


1tab. Every 6-8 hours


It should be noted that the fifth day of use of the drug on smoking should be forgotten.

In the instruction, among the special instructions, emphasis is placed on the fact that the medicine should be used only with the conscious intention to get rid of tobacco dependence. Taking the drug in parallel with smoking cigarettes can cause nicotine intoxication.


Overdose Tabex symptoms:

  • feeling nauseous;
  • the urge to vomit;
  • dilated pupils;
  • a condition characterized as general weakness;
  • presence of tachycardia, seizures;
  • paralysis of the respiratory system.

The main therapy for overdose is gastric lavage with control of blood pressure and the number of heartbeats, as well as the resumption of respiratory function. In particularly difficult situations, infusion solutions, anticonvulsant drugs, cardiotonic substances and analeptics are used.

Interactions with other drugs

As for the interaction of Tabex with other drugs, the flyer says about the ban on its simultaneous use with a group of anti-tuberculosis drugs.

The medicine does not affect the patient's mental activity without affecting the ability to drive the vehicle.

Storage conditions

According to the requirements for storage of medicines, Tabex, as a potent substance, is included in group B. On the territory of the pharmacy, these pharmacological preparations, taking into account the purpose (antibiotics, vitamins, etc.) are placed in separate cabinets with locks marked "B".

Home storage conditions Tabex mean the presence of a dry, light and waterproof place, where small children can not reach. Storage temperature should not exceed 25 ° C.

Shelf life

Shelf life according to the instruction is two years from the date of manufacture.

It is important to know!

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Last reviewed by: Aleksey Portnov , medical expert, on 01.06.2018
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To simplify the perception of information, this instruction for use of the drug "Tabex" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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