Chlamydia suppositories

Currently, doctors can offer a lot of different medications for the treatment of chlamydia. The most popular among such drugs are tablets, enemas, solutions for baths and douches. This series also includes suppositories for chlamydia - they are sold in pharmacies without a prescription, but it is not advisable to buy them without consulting a doctor. Which suppositories are most effective and how to use them: this is what our article is about.

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Indications for the use of suppositories for chlamydia

Chlamydia is a common sexually transmitted disease, one of the ways of spreading which is considered to be open sexual contact with an infected partner. Chlamydia are intracellular parasites capable of reproduction. They are something between a virus and a bacterium, so the disease is quite difficult to diagnose and treat. Unfortunately, in most cases, chlamydia is detected already at the chronic stage of the disease. This is due to the poorly expressed clinical picture of chlamydia. However, modern medicine does not stand still, and every year more and more new medications appear that allow you to effectively influence the pathology and cure it forever.

The therapeutic regimen should consist of several different drugs, since the pathogen quickly becomes resistant to any one drug. For this reason, medications for chlamydia, including suppositories, should be selected from different pharmacological groups, with different spectrum and degree of impact.

It is better not to self-medicate: after a few days of treatment, chlamydia will develop resistance to the drug and will stop responding to the chosen medicine.

Pharmacodynamics

The pharmacodynamics of suppositories for chlamydia directly depends on the composition and pharmacological activity of a particular drug.

Interferons have an immunomodulatory effect, stimulating mainly the cellular stage of immune protection (phagocytosis, activity of T-killers and T-helpers). Activation of leukocytes entails the removal of the inflammatory reaction, normalization of IgA synthesis. In addition, vital processes in the cellular structures of pathogenic microorganisms are disrupted.

Antiseptic suppositories interact with microbial cells, disrupt their viability, inhibit reproduction and development, which leads to the death of the pathogenic microorganism.

The use of antiseptic suppositories helps not only in the fight against parasitic bacteria. Such suppositories can be used to prevent sexually transmitted infections (in particular, chlamydia).

Pharmacokinetics

Vaginal suppositories and suppositories are absorbed through the mucous membranes when used locally. The absorption of active components into the systemic bloodstream when used intravaginally is insignificant. Excretion from the body occurs mainly through the liver and gallbladder, to a lesser extent through the urinary system.

Rectal suppositories allow the active ingredients to be absorbed through the rectal mucosa, which ensures that the drug enters the bloodstream directly, without the intervention of the digestive system. The concentration of the drug in the blood increases during the first hour after the suppository is used. The level of active substances may gradually decrease, for about 12 hours, after which the drug must be re-administered.

Names of suppositories for chlamydia

Medicines in the form of suppositories or candles are actively used in the treatment of chlamydia in both female and male patients. Suppositories for chlamydia are divided into 2 types:

• rectal suppositories - they are inserted into the rectum, from where the medicinal components are absorbed into the bloodstream;
• Vaginal suppositories for chlamydia are suppositories for chlamydia in women, which are intended for local action on the affected area.

There is no point in determining which type of suppositories is better and which is worse. Treatment of chlamydia is prescribed taking into account the individual characteristics of the body, since there is no universal treatment for this disease.

Popular names of suppositories for chlamydia are as follows:

1. Hexicon is a drug based on chlorhexidine, an antiseptic substance that has a detrimental effect on gram (-) and gram (+) microbes and protozoa. It is capable of inhibiting the development of chlamydia, treponema, ureaplasma, gardnerella, trichomonas, etc., without simultaneously destroying the beneficial microflora of the vaginal environment. Hexicon suppositories for chlamydia are prescribed even to pregnant and lactating women: this drug is non-toxic and does not have a negative effect on pregnancy and the fetus;
2. Polyoxidonium (azoximer bromide) is an immunomodulator that increases the body's resistance to infection, and also affects phagocytes and killer cells and stimulates the formation of antibodies. Polyoxidonium potentiates the effect of antibiotics and reduces the duration of treatment, can be used both rectally and vaginally;
3. Betadine (Povidone-Iodine) is an antiseptic and disinfectant, has pronounced antimicrobial activity. Destroys staphylococcus, E. coli, fungi, viruses and protozoa, as well as gram (+) and gram (-) bacteria. In case of chlamydia, the drug acts quite quickly and effectively;
4. Genferon is an antiviral interferon. It improves local and systemic protection of the body, has an antiviral and antimicrobial effect. It disrupts vital processes in pathogenic cells: viruses, chlamydia, ureaplasma, mycoplasma, trichomonas, fungi. Genferon can be used rectally or vaginally;
5. Viferon is an interferon with antiviral activity. It acts as an antiviral drug, immunomodulator, and also a means of suppressing excessive proliferation of various cells. Viferon suppositories are successfully used for chlamydia due to the fact that this drug can disrupt the cell structure of not only the virus, but also some other microorganisms, for example, chlamydia. The use of Viferon suppositories does not lead to the formation of antibodies that neutralize interferon, even with prolonged use of the drug.

What suppositories are used most often for chlamydia?

Firstly, these are antimicrobial suppositories that have antibacterial activity, inhibiting the development and suppressing the vital processes of chlamydia.

Secondly, these are immunomodulatory suppositories, the action of which is aimed at strengthening the body's defenses. It is no secret that chlamydia has a detrimental effect on the immune system, thereby creating the preconditions for the infection to flourish. Immunomodulatory suppositories help to raise local and systemic immune protection, which forces the body to fight the infection on its own.

Method of administration and dosage

Vaginal suppositories should be inserted deeper into the vaginal cavity, 1 suppository 1 to 2 times a day. Duration of therapy is 1 to 3 weeks, at the discretion of the attending physician.

In chronic cases, treatment can last up to 3 months, the dosage is individual.

Rectal suppositories are usually prescribed for male patients. Use 1 piece 2 times a day, from 10 to 25 days per course.

If the doctor deems it necessary, he may prescribe a repeat course of treatment, with the dose and frequency of administration of the drug, as well as the duration of therapy, determined individually.

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Using Chlamydia Suppositories During Pregnancy

Chlamydia during pregnancy is not such a rare problem, so the question of using suppositories for chlamydia by pregnant women is always relevant. Not all women decide to take antibiotics in tablets during pregnancy. Suppositories are a different matter: their effect on the body is less pronounced, which allows avoiding negative effects on the fetus. Which suppositories can be used to treat chlamydia during pregnancy, and which cannot?

• Viferon is approved for use from the second trimester of pregnancy (approximately from the 14th week), as well as during breastfeeding.
• Genferon – approved for use from 12 weeks.
• Betadine – not used during pregnancy.
• Polyoxidonium is not prescribed during pregnancy.
• Hexicon is approved for use by pregnant and lactating women.

Some experts are of the opinion that chlamydia treatment should not be done at all during pregnancy. However, there is no consensus on this matter, so make a decision on the possibility of such therapy after consulting, if possible, with several doctors. Naturally, self-treatment of chlamydia, especially during pregnancy, is out of the question.

Contraindications to the use of suppositories for chlamydia

Are there any contraindications to the use of suppositories for chlamydia?

• Individual intolerance to the components of the drug.
• An allergic or autoimmune disease in the acute stage.
• In some cases – pregnancy.
• Acute renal failure.

If you have any chronic diseases and you are not sure about the possibility of taking a particular drug, consult your doctor.

Before using suppositories, be sure to read the instructions for the drug.

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Side effects of suppositories for chlamydia

Suppositories for chlamydia may have side effects in less than 1% of cases of their use. Most often, such effects are expressed in the form of allergic reactions: redness, itching in the vagina, discharge, burning. All of the listed symptoms usually disappear within 72 hours if this drug is discontinued.

Overdose

Rectal and vaginal use of suppositories completely eliminates the possibility of overdose. Not a single case of overdose with suppositories has been recorded.

Interactions with other drugs

In most cases, suppositories for chlamydia are compatible and combine well with all medications that can be used in the treatment of chlamydia. These can be antibiotics, immunomodulators and other drugs.

The use of interferons simultaneously with other antiviral or antimicrobial agents mutually enhances each other's effectiveness.

The effect of interferons is also enhanced when taken in combination with tocopherol or ascorbic acid.

There is no information about other interactions of chlamydia suppositories with other medications.

Storage conditions

Suppositories for chlamydia should be stored in a refrigerator, from +2°C to +8°C. Freezing of medicines is unacceptable.

Keep children away from places where medicines are stored.

The shelf life of suppositories is about 2 years. The exact shelf life should be indicated on the packaging of the drug.

Reviews of suppositories for chlamydia

If you analyze the reviews about suppositories for chlamydia, they are generally positive. Many advise never to interrupt the treatment prescribed by the doctor and not to replace the drugs with others on your own, as they may be less effective.

In order to prevent leakage of the drug after softening of the vaginal suppository, the patient is recommended to lie on her back and in this position insert the suppository as deeply as possible. Then, if possible, lie down for at least half an hour. If the suppository is inserted incorrectly or not deeply, it may leak out before it is absorbed into the mucous membranes.

During treatment with suppositories, you should not additionally douche or wash your genitals with disinfectant solutions.

Sexual relations must be excluded during therapy, otherwise the treatment may be meaningless.

During menstruation, treatment is continued in most cases.

When choosing suppositories for chlamydia, remember that no matter how popular and safe they are, all medications have their own contraindications and side effects. Do not self-medicate and be sure to listen to your doctor's advice.