Sodium iodide

Sodium iodide is intended to regulate the functioning of the thyroid gland.

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Indications Sodium iodide

Sodium Iodide is prescribed:

• with excessive production of thyroid hormones by the thyroid gland;
• with an enlarged thyroid gland;
• as a prophylactic agent in case of high radioactive background;
• before surgical interventions in case of thyroid hormone intoxication;
• for respiratory diseases, including bronchial asthma;
• for inflammatory eye diseases;
• as an adjuvant treatment for syphilis.

Release form

Sodium iodide is available as a white powder that is odorless and has a salty taste. The powder dissolves in water, glycerin, alcohol and is intended for oral administration.

The drug is also available as an injection solution.

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Pharmacodynamics

Sodium iodide regulates the production of hormones by the thyroid gland, in particular inhibits the production of thyroid hormones.

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Pharmacokinetics

Sodium iodide has antiseptic properties, participates in the enzymatic breakdown of proteins, and stimulates the production of sputum at a reflex level. With an increased radioactive background, taking the drug allows you to protect the thyroid gland from the harmful effects of radiation and prevent the accumulation of radioactive iodine.

The half-life is approximately 10 minutes. It accumulates mainly in the thyroid gland, and is excreted by the kidneys and feces within 24 hours (the figures may vary depending on the patient's age, gender, and functional state of the thyroid gland).

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Dosing and administration

Sodium iodide is taken in a course determined by the attending physician, taking into account the disease and the patient's condition.

The drug is usually taken as a solution (in severe cases, sodium iodide is administered intravenously). From 0.9 to 4 g of the substance is prescribed per day; it is recommended to divide the daily dose into several doses.

The dissolved powder should be washed down with drinks that protect the gastric mucosa (jelly, milk).

When administered intravenously, the drug is administered once every few days; the course of treatment is 8-12 injections.

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Use Sodium iodide during pregnancy

Sodium iodide is not used to treat pregnant women.

Contraindications

Sodium iodide is not used in case of allergy to iodine, kidney disease, inflammatory processes on the skin, including acne, during pregnancy, tuberculosis, allergic dermatitis.

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Side effects Sodium iodide

Sodium iodide can provoke inflammatory processes in the respiratory tract and mucous membranes (nasal and oral cavities, mucous membranes of the eyes), runny nose, skin rash, angioedema.

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Overdose

Sodium iodide in high doses can provoke tachycardia, increased photosensitivity, fever, sleep disturbance, and irritability.

If symptoms of an overdose occur, stop taking the drug and consult a specialist. It is also necessary to completely eliminate the use of salicylates (sedalgin, askofen, citramon, cefekon, etc.).

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Interactions with other drugs

Sodium iodide is incompatible with salicylates, alkaloids and other nitrogenous bases (theophylline, atropine, caffeine, etc.).

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Storage conditions

Sodium iodide should be stored in a place protected from light and moisture, and should be kept out of reach of children. Sodium iodide in the open air begins to dampen and release iodine, which can reduce its therapeutic properties.

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Shelf life

Sodium iodide has a shelf life of 12 months from the date of manufacture.

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